Pascaline Boudou‐Rouquette
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View article: Factors associated with medication adherence trajectory among patients treated with oral anticancer drugs: a multicentre cohort study
Factors associated with medication adherence trajectory among patients treated with oral anticancer drugs: a multicentre cohort study Open
View article: Orthopedic Surgical Management of Soft Tissue Sarcomas in a Referral Center: 5-Year Oncological Outcomes
Orthopedic Surgical Management of Soft Tissue Sarcomas in a Referral Center: 5-Year Oncological Outcomes Open
IV; retrospective study.
View article: Data from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma
Data from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma Open
Purpose:No universal circulating biomarker exists for soft-tissue sarcoma (STS) and bone sarcoma. We report the translational relevance of a Droplet Digital PCR (ddPCR) assay allowing universal, specific, and dynamic detection of sarcoma-r…
View article: Supplementals 1 from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma
Supplementals 1 from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma Open
Supplementals
View article: Supplemental Data 1 from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma
Supplemental Data 1 from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma Open
Supplemental Data 1
View article: Supplemental Data 2 from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma
Supplemental Data 2 from Droplet Digital PCR Assay for Detection and Monitoring of Universally Methylated ctDNA in Patients with Sarcoma Open
Supplemental Data 2
View article: The Fibrosis‐4 score is associated with overall mortality and severe haematological toxicity in older patients with cancer: Analysis of two prospective cohort studies
The Fibrosis‐4 score is associated with overall mortality and severe haematological toxicity in older patients with cancer: Analysis of two prospective cohort studies Open
The management of older adults with cancer is complicated. Although the liver metabolizes most chemotherapy agents, the predictive value of the liver status in older patients with cancer remains unclear. Here, we evaluated the association …
View article: Insights Into Non‐Classic Primary Bone Sarcomas in Children, Adolescents, and Young Adults: A French Descriptive Study
Insights Into Non‐Classic Primary Bone Sarcomas in Children, Adolescents, and Young Adults: A French Descriptive Study Open
Background Bone sarcomas other than osteosarcoma, chondrosarcoma, and Ewing sarcoma represent a challenge in care because they are uncommon, especially in children, adolescents, and young adults (AYA). Methods We conducted a retrospective …
View article: CD57+ EMRA CD8+ T cells in cancer patients over 70: associations with prior chemotherapy and response to anti-PD-1/PD-L1 therapy
CD57+ EMRA CD8+ T cells in cancer patients over 70: associations with prior chemotherapy and response to anti-PD-1/PD-L1 therapy Open
These findings underscore the impact of prior chemotherapy on expanding the pool of senescent T cells, particularly CD57+ EMRA CD8+ T and CD57+ GRZB+ EMRA CD8+ T cells, whose expansion…
View article: Differential predictive value of resident memory CD8 <sup>+</sup> T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy
Differential predictive value of resident memory CD8 <sup>+</sup> T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy Open
Background A high density of resident memory T cells (T RM ) in tumors correlates with improved clinical outcomes in immunotherapy-treated patients. In most clinical studies, T RM are defined by the CD103 marker. However, it is clearly est…
View article: Hospital care trajectories of older adults with cancer and the associated clinical profiles
Hospital care trajectories of older adults with cancer and the associated clinical profiles Open
Background The longitudinal hospital care experiences of older adults with cancer, from the treatment decision-making process until their end of life, remain unexplored. We examined the hospital care trajectories of these patients and iden…
View article: Health literacy and the use of digital tools in older patients with cancer and their younger counterparts: A multicenter, nationwide study
Health literacy and the use of digital tools in older patients with cancer and their younger counterparts: A multicenter, nationwide study Open
View article: Doxorubicin–Trabectedin with Trabectedin Maintenance in Leiomyosarcoma
Doxorubicin–Trabectedin with Trabectedin Maintenance in Leiomyosarcoma Open
Combination therapy with doxorubicin and trabectedin induction, followed by trabectedin maintenance, was associated with improved overall survival and progression-free survival, as compared with doxorubicin alone, among patients with metas…
View article: Performance of AI for preoperative CT assessment of lung metastases: Retrospective analysis of 167 patients
Performance of AI for preoperative CT assessment of lung metastases: Retrospective analysis of 167 patients Open
AI significantly increases the sensitivity of preoperative detection of lung metastases and enables earlier detection, with a significant potential benefit for patient management.
View article: Prognostic impact of neurocognitive disorders in older patients with cancer: the ELCAPA prospective cohort study
Prognostic impact of neurocognitive disorders in older patients with cancer: the ELCAPA prospective cohort study Open
Our results suggest that the presence of a major NCD has direct prognostic value (independently of other geriatric factors, the type of cancer and the treatment strategy) in older patients with a solid cancer.
View article: Differential predictive value of resident memory CD8<sup>+</sup>T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapy
Differential predictive value of resident memory CD8<sup>+</sup>T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapy Open
A high density of resident memory T cells (T RM ) in tumors correlates with improved clinical outcomes in immunotherapy-treated patients. However, in preclinical models, only some subpopulations of T RM are associated with cancer vaccine e…
View article: Comparison of the prognostic value of eight nutrition-related tools in older patients with cancer: A prospective study
Comparison of the prognostic value of eight nutrition-related tools in older patients with cancer: A prospective study Open
After adjustment for relevant prognostic factors, all eight nutrition-related tools/markers were independently associated with 1-year mortality in older patients with cancer. Depending on the time or context of the GA, physicians do not al…
View article: Hospital Care Trajectories of Older Adults with Cancer and the Associated Clinical Profiles: linking a French Prospective Cohort Study and a Clinical Data Warehouse
Hospital Care Trajectories of Older Adults with Cancer and the Associated Clinical Profiles: linking a French Prospective Cohort Study and a Clinical Data Warehouse Open
Background The longitudinal hospital care experiences of older adults with cancer, from the treatment decision-making process until their end of life, remain unexplored. We examined the hospital care trajectories of these patients and iden…
View article: Improved nationwide survival of sarcoma patients with a network of reference centers
Improved nationwide survival of sarcoma patients with a network of reference centers Open
View article: Regorafenib in patients with advanced Ewing sarcoma: results of a non-comparative, randomised, double-blind, placebo-controlled, multicentre Phase II study
Regorafenib in patients with advanced Ewing sarcoma: results of a non-comparative, randomised, double-blind, placebo-controlled, multicentre Phase II study Open
View article: Immunologic constant of rejection as a predictive biomarker of immune checkpoint inhibitors efficacy in non-small cell lung cancer
Immunologic constant of rejection as a predictive biomarker of immune checkpoint inhibitors efficacy in non-small cell lung cancer Open
View article: A systematic review of recent phase-II trials in refractory or recurrent osteosarcoma: Can we inform future trial design?
A systematic review of recent phase-II trials in refractory or recurrent osteosarcoma: Can we inform future trial design? Open
View article: Burden of grade 3 or 4 liver injury associated with immune checkpoint inhibitors
Burden of grade 3 or 4 liver injury associated with immune checkpoint inhibitors Open
There is concern about liver injury in patients with cancer exposed to immune checkpoints inhibitors (ICIs). We investigated the burden of grade 3/4 liver injury after treatment with ICIs in a multicentric cohort of patients with cancer. O…
View article: Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis
Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis Open
Supplementary Figure from Lack of Prognostic Value of CTNNB1 Mutation Profile in Desmoid-Type Fibromatosis
View article: Supplementary Data from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis
Supplementary Data from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis Open
Supplementary Data from Lack of Prognostic Value of CTNNB1 Mutation Profile in Desmoid-Type Fibromatosis
View article: Supplementary Data from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis
Supplementary Data from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis Open
Supplementary Data from Lack of Prognostic Value of CTNNB1 Mutation Profile in Desmoid-Type Fibromatosis
View article: Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis
Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis Open
Supplementary Figure from Lack of Prognostic Value of CTNNB1 Mutation Profile in Desmoid-Type Fibromatosis
View article: Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis
Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis Open
Supplementary Figure from Lack of Prognostic Value of CTNNB1 Mutation Profile in Desmoid-Type Fibromatosis
View article: Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis
Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis Open
Supplementary Figure from Lack of Prognostic Value of CTNNB1 Mutation Profile in Desmoid-Type Fibromatosis
View article: Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis
Supplementary Figure from Lack of Prognostic Value of <i>CTNNB<sub>1</sub></i> Mutation Profile in Desmoid-Type Fibromatosis Open
Supplementary Figure from Lack of Prognostic Value of CTNNB1 Mutation Profile in Desmoid-Type Fibromatosis