Explanipedia

Insecticide-treated bednet coverage in Africa 2006-2024: a spatiotemporal analysis of net ownership, use, age and type Open

Eugene Tan, Mauricio van den Berg, Camilo Vargas, Tasmin L. Symons, Peter W. Gething · 2025

Since their rapid adoption from the mid 2000s, insecticide-treated nets (ITNs) have been one of the most ubiquitous and impactful malaria interventions in Africa. Facing insecticide resistance and ever-increasing resource constraints, ther…

Estimating rates of treatment delay for malaria fevers among children in Sub-Saharan Africa 2006–2022 Open

Jailos Lubinda, Susan F. Rumisha, Paulina A. Dzianach, Michael McPhail, Adam Saddler , et al. · 2025

A malaria seasonality dataset for sub-Saharan Africa Open

Francesca Sanna, Suzanne Keddie, Tara F. Boyhan, Paulina A. Dzianach, Michael McPhail , et al. · 2025

Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions Open

Oliver J. Watson, Thu Nguyen-Anh Tran, Robert Zupko, Tasmin L. Symons, Rebecca Thomson , et al. · 2025

Since their first detection in 2010, Plasmodium falciparum malaria parasites lacking the P. falciparum histidine-rich protein 2 gene (pfhrp2) have been observed in 40 of 47 surveyed countries, as documented by the World Health Organization…

Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions Open

Oliver J. Watson, Thu Nguyen-Anh Tran, Robert Zupko, Tasmin L. Symons, Rebecca Thomson , et al. · 2025

Mapping Bacillus Calmette–Guérin vaccination coverage in Africa from 1990 to 2022: a novel spatiotemporal modelling study Open

Alemneh Mekuriaw Liyew, Beth Gilmour, Archie Clements, Peter W. Gething, Susan F. Rumisha , et al. · 2025

For the Amharic, Icibemba and Swahili translations of the abstract see Supplementary Materials section.

Dynamical and time series approach to understanding compartmental stock and flow models: a case study in malaria intervention models Open

Eugene Tan, Camilo Vargas, Mauricio van den Berg, Tasmin L. Symons, Peter W. Gething · 2025

Insecticide treated nets (ITNs) represent one of the most cost-effective malaria control measures that is widely adopted today. The construction of mechanistic models to describe structural distribution, ownership and attrition of ITNs are…

Reductions in malaria cases after deployment of dual-active ingredient insecticide treated nets (ITNs) in Ghana – a Bayesian interrupted time series analysis Open

Samuel Oppong, Otubea Owusu Akrofi, Christian Atta-Obeng, Sylvester Coleman, Punam Amratia , et al. · 2025

Background Insecticide treated nets (ITNs) represent a key tool in reducing human vector contact for malaria control. However, increasing insecticide resistance of malaria vectors threatens the effectiveness of pyrethroid-only nets in redu…

Examining the overlap in lymphatic filariasis prevalence and malaria insecticide-treated net access-use in endemic Africa Open

Joanna L Whisnant, Mustafa Kamal Sikder, Gizachew Taddesse Akalu, Tsegaye Alemu, Mubarek Yesse Ashemo , et al. · 2025

Eradication and elimination strategies for lymphatic filariasis (LF) primarily rely on multiple rounds of annual mass drug administration (MDA), but also may benefit from vector control interventions conducted by malaria vector control pro…

Mapping tuberculosis prevalence in Africa using a Bayesian geospatial analysis Open

Alemneh Mekuriaw Liyew, Eyob Alemayehu Gebreyohannes, André Python, Archie Clements, Beth Gilmour , et al. · 2025

Small-area geographical variation in the prevalence of diabetes amongst Australian youth aged <20 years in 2021 Open

Ewan Cameron, Song Zhang, Aveni Haynes, Peter W. Gething · 2025

Mapping residual malaria transmission in Vietnam Open

Michael McPhail, Yalemzewod Assefa Gelaw, Xuân Th̆áng Nguyễn, Win Han Oo, Freya J. I. Fowkes , et al. · 2025

This work was supported, in whole or in part, by the Bill & Melinda Gates Foundation [INV-055192 and INV-009390/OPP1197730]. The conclusions and opinions expressed in this work are those of the author(s) alone and shall not be attributed t…

Estimating the potential malaria morbidity and mortality avertable by the President’s Malaria Initiative in 2025: a geospatial modelling analysis Open

Tasmin L. Symons, Jailos Lubinda, Michael McPhail, Adam Saddler, Mauricio van den Berg , et al. · 2025

Background Since its inception in 2005, the President’s Malaria Initiative (PMI) has played a major role in the reductions in malaria morbidity and mortality witnessed across Africa. With the status of PMI funding and operations currently …

Fine scale spatial mapping of urban malaria prevalence for microstratification in an urban area of Ghana Open

Samuel Oppong, David Dosoo, Nana Yaw Peprah, George Asumah Adu, Wahjib Mohammed , et al. · 2025

Background Malaria in urban areas is a growing concern in most sub-Saharan African countries. The growing threats of Anopheles stephensi and insecticide resistance magnify this concern and hamper elimination efforts. It is therefore impera…

Mapping the global prevalence, incidence, and mortality of Plasmodium falciparum and Plasmodium vivax malaria, 2000–22: a spatial and temporal modelling study Open

Daniel J. Weiss, Paulina A. Dzianach, Adam Saddler, Jailos Lubinda, Annie J. Browne , et al. · 2025

Bill & Melinda Gates Foundation and Australian National Health and Medical Research Council.

Projected ecological and disruptive impacts of climate change on malaria in Africa Open

Tasmin L. Symons, Alexander Moran, Ann Balzarolo, Camilo Vargas, M.C. Robertson , et al. · 2025

The implications of climate change for malaria eradication in the 21 st century remain poorly resolved. Many studies have focussed on parasite and vector ecology in isolation, neglecting the interactions between climate, malaria control, a…

Estimating the Incidence of Severe Malaria in Children in Sub-Saharan Africa 2015 to 2024 Open

Annie J. Browne, Francesca Sanna, Punam Amratia, Hunter Baggen, Paulina A. Dzianach , et al. · 2025

Malaria treatment for prevention: a modelling study of the impact of routine case management on malaria prevalence and burden Open

Flavia Camponovo, Aurélie Jeandron, Laura Skrip, Monica Golumbeanu, Clara Champagne , et al. · 2024

Estimating the impact of imported malaria on local transmission in a near elimination setting: a case study from Bhutan Open

Kinley Wangdi, H. Juliette T. Unwin, Kinley Penjor, Tsheten Tsheten, Tobgyal , et al. · 2024

High-resolution spatio-temporal risk mapping for malaria in Namibia: a comprehensive analysis Open

Song Zhang, Punam Amratia, Tasmin L. Symons, Susan F. Rumisha, Su Yun Kang , et al. · 2024

Malaria treatment for prevention: a modelling study of the impact of routine case management on malaria prevalence and burden Open

Flavia Camponovo, Aurélie Jeandron, Laura Skrip, Monica Golumbeanu, Clara Champagne , et al. · 2024

Background Testing and treating symptomatic malaria cases is crucial for case management, but it may also prevent future illness by reducing mean infection duration. Measuring the impact of effective treatment on burden and transmission vi…

Fine-scale maps of malaria incidence to inform risk stratification in Laos Open

Su Yun Kang, Punam Amratia, Julia C. Dunn, Phoutnalong Vilay, Mark Connell , et al. · 2024

Geospatial joint modeling of vector and parasite serology to microstratify malaria transmission Open

Ellen Kearney, Punam Amratia, Su Yun Kang, Paul A. Agius, Kefyalew Addis Alene , et al. · 2024

The World Health Organization identifies a strong surveillance system for malaria and its mosquito vector as an essential pillar of the malaria elimination agenda. Anopheles salivary antibodies are emerging biomarkers of exposure to mosqui…

A situational assessment of treatments received for childhood diarrhea in the Federal Republic of Nigeria Open

Ezra Gayawan, Ewan Cameron, Tolu Okitika, Osafu Augustine Egbon, Peter W. Gething · 2024

We assess progress towards improved case management of childhood diarrhea in Nigeria over a period of targeted health systems reform from 2013 to 2018. Individual and community data from three Demographic and Health Survey rounds are lever…

Global risk of selection and spread of<i>Plasmodium falciparum</i>histidine-rich protein 2 and 3 gene deletions Open

Oliver J. Watson, Thu Nguyen-Anh Tran, Robert Zupko, Tasmin L. Symons, Rebecca Thomson , et al. · 2023

In the thirteen years since the first report of pfhrp2 -deleted parasites in 2010, the World Health Organization (WHO) has found that 40 of 47 countries surveyed worldwide have reported pfhrp2/3 gene deletions. Due to a high prevalence of …

Trends in treatment-seeking for fever in children under five years old in 151 countries from 1990 to 2020 Open

Huong Lan Thi Nguyen, Paulina A. Dzianach, Paul Castle, Susan F. Rumisha, Jennifer Rozier , et al. · 2023

Access to medical treatment for fever is essential to prevent morbidity and mortality in individuals and to prevent transmission of communicable febrile illness in communities. Quantification of the rates at which treatment is accessed is …

Cholera risk in Lusaka: A geospatial analysis to inform improved water and sanitation provision Open

Peter W. Gething, Sophie Ayling, Josses Mugabi, Odete Duarte Muximpua, Solomon Sitinadziwe Kagulura , et al. · 2023

Urbanization combined with climate change are exacerbating water scarcity for an increasing number of the world’s emerging cities. Water and sanitation infrastructure (WSS), which in the first place was largely built to cater only to a sma…

Impacts on Human Movement in Australian Cities Related to the COVID-19 Pandemic Open

Daniel J. Weiss, Tara F. Boyhan, Mark Connell, Kefyalew Addis Alene, Paulina A. Dzianach , et al. · 2023

No studies have yet examined high-resolution shifts in the spatial patterns of human movement in Australia throughout 2020 and 2021, a period coincident with the repeated enactment and removal of varied governmental restrictions aimed at r…

Cholera Risk in Lusaka: A Geospatial Analysis to Inform Improved Water and Sanitation Provision Open

Peter W. Gething, Sophie Ayling, Josses Mugabi, Odete Duarte Muximpua, George Joseph , et al. · 2023

Urbanization combined with climate change are exacerbating water scarcity for an increasing number of the world's emerging cities. Water and sanitation infrastructure, which in the first place was largely built to cater only to a small sub…

An archetypes approach to malaria intervention impact mapping: a new framework and example application Open

Amelia Bertozzi-Villa, Caitlin Bever, Jaline Gerardin, Joshua L. Proctor, Meikang Wu , et al. · 2023

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