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View article: Mepolizumab versus benralizumab for eosinophilic granulomatosis with polyangiitis (EGPA): A European real-life retrospective comparative study
Mepolizumab versus benralizumab for eosinophilic granulomatosis with polyangiitis (EGPA): A European real-life retrospective comparative study Open
View article: Mepolizumab vs Benralizumab for Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European comparative study Short running title: Mepolizumab versus Benralizumab for EGPA
Mepolizumab vs Benralizumab for Eosinophilic Granulomatosis with Polyangiitis (EGPA): a European comparative study Short running title: Mepolizumab versus Benralizumab for EGPA Open
View article: Angioedema due to Acquired C1-Inhibitor Deficiency Associated With Monoclonal Gammopathies of Undetermined Significance Characteristics of a French National Cohort
Angioedema due to Acquired C1-Inhibitor Deficiency Associated With Monoclonal Gammopathies of Undetermined Significance Characteristics of a French National Cohort Open
Complete remission of AAE-C1-INH is correlated to complete remission of the underlying hematological malignancy, as defined by an undetectable serum monoclonal immunoglobulin. In our MGUS-associated acquired angioedema cohort, we recorded …
View article: Haematological features of telomere biology disorders diagnosed in adulthood: A French nationwide study of 127 patients
Haematological features of telomere biology disorders diagnosed in adulthood: A French nationwide study of 127 patients Open
Summary Data on haematological features of telomere biology disorders (TBD) remain scarce. We describe haematological, extra‐haematological characteristics and prognosis of 127 genetically confirmed TBD patients diagnosed after the age of …
View article: French protocol for the diagnosis and management of systemic lupus erythematosus
French protocol for the diagnosis and management of systemic lupus erythematosus Open
View article: Acid sphingomyelinase deficiency in France: a retrospective survival study
Acid sphingomyelinase deficiency in France: a retrospective survival study Open
Background Acid sphingomyelinase deficiency (ASMD) or Niemann–Pick disease types A, A/B, and B is a progressive, life-limiting, autosomal recessive disorder caused by sphingomyelin phosphodiesterase 1 ( SMPD1 ) gene mutations. There is a n…
View article: The CARMEN-France registry of adult patients with immune thrombocytopenia and autoimmune hemolytic anemia in France
The CARMEN-France registry of adult patients with immune thrombocytopenia and autoimmune hemolytic anemia in France Open
View article: Hydroxychloroquine levels in pregnancy and materno-fetal outcomes in systemic lupus erythematosus patients
Hydroxychloroquine levels in pregnancy and materno-fetal outcomes in systemic lupus erythematosus patients Open
Objectives Data about hydroxychloroquine (HCQ) levels during pregnancy are sparse. We assessed HCQ whole-blood levels at first trimester of pregnancy as a potential predictor of maternal and obstetric/fetal outcomes in patients with system…
View article: Efficacy of Mepolizumab for the Treatment of Eosinophilic Cystitis: A Report of 2 Cases
Efficacy of Mepolizumab for the Treatment of Eosinophilic Cystitis: A Report of 2 Cases Open
International audience
View article: Benralizumab for eosinophilic granulomatosis with polyangiitis
Benralizumab for eosinophilic granulomatosis with polyangiitis Open
View article: Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity
Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity Open
View article: Occurrence of focal myositis during Behçet's disease: The identification of a specific vasculitis‐associated focal myopathy
Occurrence of focal myositis during Behçet's disease: The identification of a specific vasculitis‐associated focal myopathy Open
Aims This study aimed to report the association of focal myositis (FM) and Behçet's disease (BD) and to analyse the main characteristics of such an association. Methods This is a retrospective multicentre study of patients with BD and FM (…
View article: Population designations in biomedical research: Limitations and perspectives
Population designations in biomedical research: Limitations and perspectives Open
In biomedical research, population differences are of central interest. Variations in the frequency and severity of diseases and in treatment effects among human subpopulation groups are common in many medical conditions. Unfortunately, th…
View article: Antineutrophil Cytoplasm Antibody–Associated Vasculitides Valvular Impairment: Multicenter Retrospective Study and Systematic Review of the Literature
Antineutrophil Cytoplasm Antibody–Associated Vasculitides Valvular Impairment: Multicenter Retrospective Study and Systematic Review of the Literature Open
Objective While myocardial impairment is a predictor of poor prognosis in antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV), little is known about valvular involvement. This study aims at describing the clinical presen…
View article: Therapeutic Potential of Anti-Interferon α Vaccination on SjS-Related Features in the MRL/lpr Autoimmune Mouse Model
Therapeutic Potential of Anti-Interferon α Vaccination on SjS-Related Features in the MRL/lpr Autoimmune Mouse Model Open
Sjögren’s syndrome (SjS) is a frequent systemic autoimmune disease responsible for a major decrease in patients’ quality of life, potentially leading to life-threatening conditions while facing an unmet therapeutic need. Hence, we assessed…
View article: Attitudes of internal medicine specialists and rheumatologists towards chronic pain complaints
Attitudes of internal medicine specialists and rheumatologists towards chronic pain complaints Open
Cartesian mind/body or mind/brain dualism has profound consequences on medical practice. Not only is a symptom considered as more "real" if caused by an organic disorder than if "unexplained", but there is a moral judgement of responsibili…
View article: Pulmonary Involvement Responsive to Enzyme Replacement Therapy in an Elderly Patient with Gaucher Disease
Pulmonary Involvement Responsive to Enzyme Replacement Therapy in an Elderly Patient with Gaucher Disease Open
Type 1 Gaucher disease (GD) is a rare autosomal recessive lysosomal storage disorder caused by deficient activity of beta-glucocerebrosidase, leading to accumulation of its substrate (glucosylceramide) in macrophages of the reticuloendothe…
View article: « COVID long » : une opportunité pour approcher la complexité des syndromes fonctionnels post-infectieux
« COVID long » : une opportunité pour approcher la complexité des syndromes fonctionnels post-infectieux Open
View article: Efficiency of an Optimized Care Organization in Fibromyalgia Patients: The From Intent to Move (FIMOUV) Study Protocol of a Randomized Controlled Trial
Efficiency of an Optimized Care Organization in Fibromyalgia Patients: The From Intent to Move (FIMOUV) Study Protocol of a Randomized Controlled Trial Open
Introduction: Fibromyalgia (FM) is characterized by multiple symptoms including pain, fatigue, and sleep disorders, altering patient's quality of life. In the absence of effective pharmacological therapy, the last European guidelines recom…
View article: Patient-Centered Medicine: A Necessary Condition for the Management of Functional Somatic Syndromes and Bodily Distress
Patient-Centered Medicine: A Necessary Condition for the Management of Functional Somatic Syndromes and Bodily Distress Open
This paper argues that “functional,” “medically unexplained,” or “somatoform” symptoms and disorders necessarily require a patient-centered approach from the clinicians. In the first part, I address the multiple causes of the patients' suf…
View article: COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study
COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study Open
View article: Immunomonitoring du rituximab appliqué aux maladies auto-immunes : une aide pour la pratique clinique ?
Immunomonitoring du rituximab appliqué aux maladies auto-immunes : une aide pour la pratique clinique ? Open
View article: Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients
Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients Open
View article: French recommendations for the management of systemic necrotizing vasculitides (polyarteritis nodosa and ANCA-associated vasculitides)
French recommendations for the management of systemic necrotizing vasculitides (polyarteritis nodosa and ANCA-associated vasculitides) Open
Systemic necrotizing vasculitis comprises a group of diseases resembling polyarteritis nodosa and anti-neutrophil cytoplasmic antibody-associated vasculitis (ANCA): granulomatosis with polyangiitis, eosinophilic granulomatosis with polyang…
View article: Intensive rituximab regimen in immune‐mediated thrombotic thrombocytopenic purpura can circumvent unresponsiveness to standard rituximab treatment
Intensive rituximab regimen in immune‐mediated thrombotic thrombocytopenic purpura can circumvent unresponsiveness to standard rituximab treatment Open
The identification of a role for anti-ADAMTS13 antibodies in the pathogenesis of immune-mediated thrombotic thrombocytopenic purpura (iTTP)1 led to the use of B-cell depletion for this diagnosis. The chimaeric monoclonal anti-CD20 antibody…
View article: Fatal aspergillosis complicating severe SARS-CoV-2 infection: A case report
Fatal aspergillosis complicating severe SARS-CoV-2 infection: A case report Open
View article: Paraneoplastic subacute sensory neuropathy with triple positive antineuronal antibodies associated with small-cell lung cancer
Paraneoplastic subacute sensory neuropathy with triple positive antineuronal antibodies associated with small-cell lung cancer Open
A 67-year-old woman with a history of smoking and cardiovascular risk factors was admitted to the emergency room for uncontrolled diabetes, loss of appetite, nausea, significant weight loss and asthenia. The initial investigation, includin…
View article: Utilisation et gestion des inhibiteurs de la pompe à protons : une étude observationnelle
Utilisation et gestion des inhibiteurs de la pompe à protons : une étude observationnelle Open
View article: Clinical spectrum and therapeutic management of auto-immune myelofibrosis: a nation-wide study of 30 cases
Clinical spectrum and therapeutic management of auto-immune myelofibrosis: a nation-wide study of 30 cases Open
International audience
View article: Analysis of risk factors for complications and adverse obstetrical outcomes in women with Takayasu arteritis: a French retrospective study and literature review
Analysis of risk factors for complications and adverse obstetrical outcomes in women with Takayasu arteritis: a French retrospective study and literature review Open