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View article: Anogenital Contact Dermatitis in Spain: A <scp>REIDAC</scp> Study of Patients Undergoing Patch Testing in 2019–2024
Anogenital Contact Dermatitis in Spain: A <span>REIDAC</span> Study of Patients Undergoing Patch Testing in 2019–2024 Open
Background The REIDAC (Spanish Registry for Research in Contact Dermatitis) conducts nationwide epidemiological surveillance of contact dermatitis in Spain. Anogenital involvement within REIDAC has not been previously studied. Objectives T…
View article: Diffuse hyperpigmented macules in a 48‐year‐old woman
Diffuse hyperpigmented macules in a 48‐year‐old woman Open
A 48-year-old woman presented with a 4-year history of diffuse hyperpigmented papules beginning on the cleavage and progressing over the rest of the trunk and extremities. The lesions were mild pruritic. There were no family members with s…
View article: [Translated article] Drug Survival in Cyclosporine Treatment for Moderate to Severe Atopic Dermatitis: Analysis of the Spanish Atopic Dermatitis Registry (BIOBADATOP)
[Translated article] Drug Survival in Cyclosporine Treatment for Moderate to Severe Atopic Dermatitis: Analysis of the Spanish Atopic Dermatitis Registry (BIOBADATOP) Open
Drug survival of cyclosporine in the BIOBADATOP registry is similar to that described in other series of patients with AD and longer than that observed in the BIOBADADERM psoriasis registry.
View article: [Translated article] BIOBADATOP Spanish Atopic Dermatitis Registry: Description and Early Findings
[Translated article] BIOBADATOP Spanish Atopic Dermatitis Registry: Description and Early Findings Open
Initial findings on AEs from the Spanish BIOBADATOP registry are limited by short follow-up times precluding comparisons or calculation of crude and adjusted incidence rates. At the time of our analysis, no severe AEs had been reported for…
View article: VIP/VPAC Axis Expression in Immune-Mediated Inflammatory Disorders: Associated miRNA Signatures
VIP/VPAC Axis Expression in Immune-Mediated Inflammatory Disorders: Associated miRNA Signatures Open
Few studies have considered immune-mediated inflammatory disorders (IMID) together, which is necessary to adequately understand them given they share common mechanisms. Our goal was to investigate the expression of vasoactive intestinal pe…
View article: Growth arrest and DNA damage-inducible proteins (GADD45) in psoriasis
Growth arrest and DNA damage-inducible proteins (GADD45) in psoriasis Open
The interplay between T cells, dendritic cells and keratinocytes is crucial for the development and maintenance of inflammation in psoriasis. GADD45 proteins mediate DNA repair in different cells including keratinocytes. In the immune syst…
View article: Safety in Dermatologic Procedures: Hypertensive Crises and Potentially Fatal Arrhythmias
Safety in Dermatologic Procedures: Hypertensive Crises and Potentially Fatal Arrhythmias Open
As dermatologic surgeons often have to perform long surgeries with local anesthetic only, they should be familiar with the fundamentals of how to manage 2 potentially serious complications: Hypertensive crises and intraoperative arrhythmia…
View article: Study of Minimal Erythema Dose in a Series of Solar Urticaria
Study of Minimal Erythema Dose in a Series of Solar Urticaria Open
Reduced minimal erythema dose (MED) is an abnormal erythematous reaction to light according to the skin phototype, which is determined by phototest. MED is reduced or abnormal in some photodermatoses. However, we have not found information…
View article: Growth Arrest and DNA Damage-Inducible Proteins (GADD45) in Psoriasis
Growth Arrest and DNA Damage-Inducible Proteins (GADD45) in Psoriasis Open
The interplay between T cells, dendritic cells and keratinocytes is crucial in the development and maintenance of inflammation in psoriasis. GADD45 proteins mediate DNA repair in many cells including keratinocytes. In the immune system, GA…
View article: SDRIFE‐like rash associated with COVID‐19, clinicopathological correlation
SDRIFE‐like rash associated with COVID‐19, clinicopathological correlation Open
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE)-like rash has been recently reported as a skin manifestation potentially associated with coronavirus disease 2019 (COVID-19).1 A 73-year-old woman positive for SARS-Co…
View article: Expression of miR-135b in Psoriatic Skin and Its Association with Disease Improvement
Expression of miR-135b in Psoriatic Skin and Its Association with Disease Improvement Open
miRNAs have been associated with psoriasis since just over a decade. However, we are far from a complete understanding of their role during the development of this disease. Our objective was to characterize the cutaneous expression of miRN…
View article: Urticaria‐like lesions in COVID‐19 patients are not really urticaria – a case with clinicopathological correlation
Urticaria‐like lesions in COVID‐19 patients are not really urticaria – a case with clinicopathological correlation Open
We have read with great attention the article by 1 considering urticarial lesions as a coronavirus disease 2019 (COVID-19)-associated skin manifestation. They observed two patients with erythemato-oedematous lesions surrounded by whitish h…
View article: Utility of circulating serum miRNA profiles to evaluate the potential risk and severity of immune-mediated inflammatory disorders
Utility of circulating serum miRNA profiles to evaluate the potential risk and severity of immune-mediated inflammatory disorders Open
Immune-mediated inflammatory disorders (IMID) are a group of diseases that present inflammation as a major pathogenic mechanism. They affect 15% of the population and pose a heavy socio-economic burden. Despite the growing knowledge on the…
View article: Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis
Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis Open
Accumulating evidence on the role of Thrombospondin-1 (TSP-1) in the immune response has emerged during the last years. In spite of the importance of TSP-1 not only as anti-angiogenic factor but also as an immunomodulatory molecule, studie…
View article: Induction of Light Tolerance Using Narrowband UV-B in Solar Urticaria
Induction of Light Tolerance Using Narrowband UV-B in Solar Urticaria Open
Solar urticaria is an uncommon photodermatosis. First-line treatment is with antihistamines; second-line treatment includes induction of light tolerance using UV phototherapy. We aimed to describe and evaluate the effectiveness of a desens…
View article: Prevention and treatment of tuberculosis infection in candidates for biologic therapy: A multidisciplinary consensus statement adapted to the dermatology patient
Prevention and treatment of tuberculosis infection in candidates for biologic therapy: A multidisciplinary consensus statement adapted to the dermatology patient Open
Patients with chronic inflammatory diseases being treated with immunosuppressive drugs, and with tumor necrosis factor inhibitors in particular, have an increased risk of infection by Mycobacterium tuberculosis. Screening for latent tuberc…
View article: Response to Omalizumab in Solar Urticaria: Report of 3 Cases
Response to Omalizumab in Solar Urticaria: Report of 3 Cases Open
We report 3 cases of solar urticaria in which there was no response or limited response to first-line treatments with high-dose H1 antihistamines or phototherapy. The patients were then treated with omalizumab. Symptoms improved in 2 patie…
View article: Omalizumab in the Treatment of Chronic Inducible Urticaria
Omalizumab in the Treatment of Chronic Inducible Urticaria Open
Omalizumab is a recombinant humanized monoclonal antibody that inhibits immunoglobulin E. It has been approved for the treatment of severe asthma and chronic spontaneous urticaria refractory to other treatments. Its use in the management o…