Paul Johnson
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View article: “Paging Dr. Chatbot”: A Cross-sectional Comparison of the Emotional Content of Responses to Patient Health Queries between Physicians & Artificial Intelligence Chatbots (Preprint)
“Paging Dr. Chatbot”: A Cross-sectional Comparison of the Emotional Content of Responses to Patient Health Queries between Physicians & Artificial Intelligence Chatbots (Preprint) Open
BACKGROUND Recent surveys indicate much of the population is willing to use generative artificial intelligence (AI) for health-related inquiries. Most research has investigated the accuracy of responses produced by AI chatbots, while othe…
View article: Nitrogen status of mixed clover and Kentucky bluegrass dicultures in a greenhouse setting
Nitrogen status of mixed clover and Kentucky bluegrass dicultures in a greenhouse setting Open
Incorporating clover into lawns may reduce fertilizer applications and improve pollinator forage; however, much of the recent research has focused on white clover ( Trifolium repens ), while other clovers have not been as widely researched…
View article: Social security and retirement around the world: lessons from a long-term collaboration
Social security and retirement around the world: lessons from a long-term collaboration Open
Declining labor force participation of older men throughout the 20th century and recent increases in participation have generated substantial interest in understanding the effect of public pensions on retirement. The National Bureau of Eco…
View article: Clover (Trifolium spp.) Inclusion in Kentucky Bluegrass (Poa pratensis) Lawns
Clover (Trifolium spp.) Inclusion in Kentucky Bluegrass (Poa pratensis) Lawns Open
Historically, white clover ( Trifolium repens ) seed was included in turfgrass seed mixtures to provide biodiversity and nitrogen (N) to lawns. White clover dicultures have been studied recently for inclusion in both warm- and cool-season …
View article: Living standards, poverty and inequality in the UK: 2024 (Presentations)
Living standards, poverty and inequality in the UK: 2024 (Presentations) Open
Manifestos leave voters guessing over policy on tax and spending, and on future size and shape of state Debt is at its highest level in more than 60 years.Taxes are at near enough the highest ever level seen in the UK.They have risen more …
View article: UK Withdrawal From the European Convention on Human Rights: A Disaster for lgbt People
UK Withdrawal From the European Convention on Human Rights: A Disaster for lgbt People Open
Since the European Convention on Human Rights entered into force in 1953, lesbian, gay, bisexual, and transgender people have consistently sought to utilise it as a means of challenging discrimination against them. In the United Kingdom, v…
View article: Constraints and trade-offs for the next government
Constraints and trade-offs for the next government Open
The UK finds itself in an unfortunate economic and fiscal bind. Living standards have endured an unprecedentedly long stagnation. Taxes are at record levels for the UK (though remain lowto-middling by European standards). Public services a…
View article: Attitudes to inequality
Attitudes to inequality Open
Most people say, when prompted, that they are concerned about inequalities.But the degree of concern is highly variable, and the concern is not matched by a consensus about what, if anything, government should do.These beliefs and attitude…
View article: The future of the state pension
The future of the state pension Open
We suggest a new 'four-point pension guarantee' to achieve this: 1 There will be a government target level for the new state pension, expressed as a share of median full-time earnings.Increases in the state pension will in the long run kee…
View article: Comment on ‘What taxpayers, governments and tax economists do – and what they should do’
Comment on ‘What taxpayers, governments and tax economists do – and what they should do’ Open
Many economists working on tax policy, including my colleagues at the Institute for Fiscal Studies (IFS), advocate for reforms which we believe will improve the efficiency and equity of the tax system.Equalising tax rates across different …
View article: Impact of X-Ray Exposure From Computed Tomography on Wearable Insulin Delivery Devices
Impact of X-Ray Exposure From Computed Tomography on Wearable Insulin Delivery Devices Open
Background: To investigate the impact of radiation exposure from a computed tomography (CT) scanner on the functional integrity of a wearable insulin delivery system. Methods: A total of 160 Omnipods and four personal diabetes managers (PD…
View article: Challenges for the UK pension system: the case for a pensions review
Challenges for the UK pension system: the case for a pensions review Open
This report makes the case for a new review of the pension system in the UK. There are a number of key challenges facing future generations of pensioners that threaten their living standards in retirement and which, without policy action, …
View article: Supplemental Figure (1) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (1) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Comparison of metabolite levels in CBS2 vs. vector control NCM356 cells.
View article: Supplemental Figure (3) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (3) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Effect of buthionine-sulfoximine (BSO) on growth of CBS2 and vector control cells.
View article: Supplemental Figure (3) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (3) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Effect of buthionine-sulfoximine (BSO) on growth of CBS2 and vector control cells.
View article: Supplemental Table (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Table (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Gene Set Enrichment Analysis for NCM356 vector vs. CBS cells.
View article: Supplemental Table (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Table (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Gene Set Enrichment Analysis for NCM356 vector vs. CBS cells.
View article: Supplemental Figure (4) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (4) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
CBS overexpression and an H2S donor (GYY4137) enhanced NCM356 cell growth in soft agar.
View article: Supplemental Table (1) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Table (1) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Single-nucleotide polymorphism analysis for NCM356 cells.
View article: Supplemental Figure (1) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (1) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Comparison of metabolite levels in CBS2 vs. vector control NCM356 cells.
View article: Data from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Data from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
The trans-sulfuration enzyme cystathionine-β-synthase (CBS) and its product hydrogen sulfide (H2S) are aberrantly upregulated in colorectal cancers, where they contribute to tumor growth and progression by both autocrine and paracrine mech…
View article: Supplemental Figure Legends from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure Legends from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Additional description of metabolic effects and effects of hydrogen sulfide on CBS overexpression in NCM356 cells.
View article: Data from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Data from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
The trans-sulfuration enzyme cystathionine-β-synthase (CBS) and its product hydrogen sulfide (H2S) are aberrantly upregulated in colorectal cancers, where they contribute to tumor growth and progression by both autocrine and paracrine mech…
View article: Supplemental Figure Legends from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure Legends from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Additional description of metabolic effects and effects of hydrogen sulfide on CBS overexpression in NCM356 cells.
View article: Supplemental Figure (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Cysteine metabolites in NCM356 CBS cells.
View article: Supplemental Figure (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (2) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
Cysteine metabolites in NCM356 CBS cells.
View article: Supplemental Figure (4) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis
Supplemental Figure (4) from Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis Open
CBS overexpression and an H2S donor (GYY4137) enhanced NCM356 cell growth in soft agar.