Claudia Pérez
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View article: Potential Antioxidant and Neuroprotective Effect of Polysaccharide Isolated from Digüeñe Cyttaria espinosae
Potential Antioxidant and Neuroprotective Effect of Polysaccharide Isolated from Digüeñe Cyttaria espinosae Open
Alzheimer’s disease (AD) is a significant global health challenge, further exacerbated by the anticipated increase in prevalence in the coming years. The accumulation of β-amyloid peptide plays a critical role in the onset of AD; however, …
View article: Biological Effects of Polysaccharides from Bovistella utriformis as Cytotoxic, Antioxidant, and Antihyperglycemic Agents: In Vitro and In Vivo Studies
Biological Effects of Polysaccharides from Bovistella utriformis as Cytotoxic, Antioxidant, and Antihyperglycemic Agents: In Vitro and In Vivo Studies Open
Background/Objectives: This study explores the bioactive potential of Bovistella utriformis biomass and its polysaccharides (PsBu) through comprehensive biochemical and bioactivity analyses, focusing on their antioxidant, cytotoxic, and an…
View article: Distribution of Non-Structural Carbohydrates and Root Structure of Plantago lanceolata L. under Different Defoliation Frequencies and Intensities
Distribution of Non-Structural Carbohydrates and Root Structure of Plantago lanceolata L. under Different Defoliation Frequencies and Intensities Open
Plantago lanceolata L. (plantain) increases herbage dry matter (DM) production and quality during warm and dry conditions due to its deep roots and drought tolerance and reduces nitrogen losses in grazing systems compared to traditional pa…
View article: Composites Based on Eucalyptus Nitens Leaves and Natural Rubber as a Valuable Alternative for the Development of Elastomeric Materials with Low Microbiological Impact
Composites Based on Eucalyptus Nitens Leaves and Natural Rubber as a Valuable Alternative for the Development of Elastomeric Materials with Low Microbiological Impact Open
The forest industry produces several low-value by-products, such as bark, sawdust, limbs, and leaves, that are not ultimately disposed of and remain in the forests and sawmill facilities. Among these by-products are leaves, which contain n…
View article: Immunomodulatory, Antioxidant, and Potential Anticancer Activity of the Polysaccharides of the Fungus Fomitiporia chilensis
Immunomodulatory, Antioxidant, and Potential Anticancer Activity of the Polysaccharides of the Fungus Fomitiporia chilensis Open
Fomitiporia species have aroused the interest of numerous investigations that reveal their biological activity and medicinal potential. The present investigation shows the antioxidant, anticancer, and immunomodulatory activity of acidic po…
View article: <i>In vitro</i> anti-tumoral and immunomodulatory effects of acidic polysaccharides isolated from the fungus <i>Gloeosoma mirabile</i>
<i>In vitro</i> anti-tumoral and immunomodulatory effects of acidic polysaccharides isolated from the fungus <i>Gloeosoma mirabile</i> Open
Polysaccharides from wood-rooting fungi have attracted attention due to their broad pharmacological properties. Herein, we report the antitumor and immunomodulatory activities of acid polysaccharides isolated from fungi Gloeosoma mirabile.…
View article: Elephant Black Garlic’s Beneficial Properties for Hippocampal Neuronal Network, Chemical Characterization and Biological Evaluation
Elephant Black Garlic’s Beneficial Properties for Hippocampal Neuronal Network, Chemical Characterization and Biological Evaluation Open
Garlic has been used for decades as an important food and additionally for its beneficial properties in terms of nutrition and ancestral therapeutics. In this work, we compare the properties of fresh (WG) and aged (BG) extract obtained fro…
View article: ISOLATED LIGNANS OF ARAUCARIA ARAUCANA (MOLINA) K. KOCH PROVIDE WOOD PROTECTION AGAINST ATTACK BY THE XYLOPHAGOUS FUNGUS PLEUROTUS OSTREATUS (JACQ.) P. KUMM
ISOLATED LIGNANS OF ARAUCARIA ARAUCANA (MOLINA) K. KOCH PROVIDE WOOD PROTECTION AGAINST ATTACK BY THE XYLOPHAGOUS FUNGUS PLEUROTUS OSTREATUS (JACQ.) P. KUMM Open
Araucaria araucana (Molina) K. Koch is an evergreen conifer endemic of Southern Chile and it is considered a sacred tree by the Pehuenche originary people. A. araucana is endangered in the red book. The knots wood of A. araucana are resist…
View article: Amelioration of chemical and sensory properties of smoked must and wine by aeration
Amelioration of chemical and sensory properties of smoked must and wine by aeration Open
Vineyards affected by smoke from wildfires may result in wines with undesired sensory properties. This study aimed to evaluate the aeration efficiency to ameliorate the chemical and sensory properties of smoke-tainted must and wine. Smoke-…
View article: Neuroprotective Properties of Eudesmin on a Cellular Model of Amyloid-β Peptide Toxicity
Neuroprotective Properties of Eudesmin on a Cellular Model of Amyloid-β Peptide Toxicity Open
Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive impairment and memory loss. One of the hallmarks in AD is amyloid-β peptide (Aβ) accumulation, where the soluble oligomers of Aβ (A…
View article: Antioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs
Antioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs Open
The present study was carried out to determine the bioactivity of polysaccharides extracted from Euglena gracilis (EgPs). These were characterized by FT-IR and GC-MS. Cytotoxicity analyses (MTT) were performed on healthy human gingival fib…
View article: Sulfated Polysaccharide Extracted from the Green Algae Codium bernabei: Physicochemical Characterization and Antioxidant, Anticoagulant and Antitumor Activity
Sulfated Polysaccharide Extracted from the Green Algae Codium bernabei: Physicochemical Characterization and Antioxidant, Anticoagulant and Antitumor Activity Open
Codium bernabei is a green alga that grows on Chilean coasts. The composition of its structural polysaccharides is still unknown. Hence, the aim of this work is to isolate and characterize the hot water extracted polysaccharide fractions. …
View article: EVALUATION OF CYTOTOXIC EFFECT AGAINST TUMOUR CELLS OF THE ACIDIC POLYSACCHARIDES OF THE FUNGUS Nothophellinus andinopatagonicus
EVALUATION OF CYTOTOXIC EFFECT AGAINST TUMOUR CELLS OF THE ACIDIC POLYSACCHARIDES OF THE FUNGUS Nothophellinus andinopatagonicus Open
Fungal polysaccharides possess an important bioactive potential, including antioxidant and anticarcinogenic activity. The aim of this work was to determine the antioxidant activity and cytotoxicity against tumour and non-tumour cell lines …
View article: Seasonal changes in photosynthesis, phenolic content, antioxidant activity, and anatomy of apical and basal leaves of Aristotelia chilensis
Seasonal changes in photosynthesis, phenolic content, antioxidant activity, and anatomy of apical and basal leaves of Aristotelia chilensis Open
Aristotelia chilensis (Mol.) Stuntz is an evergreen species endemic to Chile. It grows in open areas or under tree canopy, and its leaves emerge in early spring and summer. The objective of this study was to determine changes in photosynth…
View article: Comparative Study of Metabolomic Profile and Antioxidant Content of Adult and In Vitro Leaves of Aristotelia chilensis
Comparative Study of Metabolomic Profile and Antioxidant Content of Adult and In Vitro Leaves of Aristotelia chilensis Open
This work aimed to identify the bioactive compounds present in adult maqui (Aristotelia chilensis) leaves from different stages of development and seasons of the year and compare them with leaves obtained from maqui plants grown in vitro. …
View article: Immunomodulatory, Antioxidant Activity and Cytotoxic Effect of Sulfated Polysaccharides from Porphyridium cruentum. (S.F.Gray) Nägeli
Immunomodulatory, Antioxidant Activity and Cytotoxic Effect of Sulfated Polysaccharides from Porphyridium cruentum. (S.F.Gray) Nägeli Open
Porphyridium cruentum is a unicellular microalga that can synthesize and secrete to the culture medium-high amounts of polysaccharides. In this study, the immunomodulatory, cytotoxic effect and antioxidant activity of the sulfated polysacc…
View article: EFFECT OF WI-FI RADIOFREQUENCIES ON THE CONTENT OF FATTY ACID AND ERGOSTEROL, A PRECURSOR OF VITAMIN D, IN IN VITRO CULTURES OF THE FUNGUS Serpula himantioides
EFFECT OF WI-FI RADIOFREQUENCIES ON THE CONTENT OF FATTY ACID AND ERGOSTEROL, A PRECURSOR OF VITAMIN D, IN IN VITRO CULTURES OF THE FUNGUS Serpula himantioides Open
In the microwave-radiofrequency spectrum, Wi-Fi is a short-range wireless broadband technology, which transmits at a frequency of 2.5 GHz. This type of technology has been positioned itself as one of the most widely used technological adva…
View article: CHEMICAL CHARACTERIZATION OF LIGNANS FROM Araucaria araucana A NATIVE CONIFER OF CHILE AND EVALUATION OF THEIR CYTOTOXICITY AND ANTIOXIDANT ACTIVITIES
CHEMICAL CHARACTERIZATION OF LIGNANS FROM Araucaria araucana A NATIVE CONIFER OF CHILE AND EVALUATION OF THEIR CYTOTOXICITY AND ANTIOXIDANT ACTIVITIES Open
Araucaria araucana is a native conifer of Chile commonly called Araucaria. The knots of Araucaria are extremely hard wood and highly rot-resistant, they can be found in the forest decades after that the tree has dead and decomposed. Here w…
View article: Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer’s Mice
Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer’s Mice Open
Alzheimer’s disease (AD) is a major public health concern worldwide. Advanced age and female sex are two of the most prominent risk factors for AD. AD is characterized by progressive neuronal loss, especially in the cortex and hippocampus,…
View article: Exposure to UV-B Radiation Leads to Increased Deposition of Cell Wall-Associated Xerocomic Acid in Cultures of <i>Serpula himantioides</i>
Exposure to UV-B Radiation Leads to Increased Deposition of Cell Wall-Associated Xerocomic Acid in Cultures of <i>Serpula himantioides</i> Open
Our study shows the morphological and chemical responses of S. himantioides to controlled doses of UV-B radiation under in vitro culture conditions. We found that increased biosynthesis of xerocomic acid was the main strategy adopted by S.…
View article: Evaluation of the effects of Ulva sp., Cryptomenia sp., Ciona intestinalis and Heliotropium sp. crude extracts as possible interfering agents on the Autophagocytosis pathway: Preliminary results
Evaluation of the effects of Ulva sp., Cryptomenia sp., Ciona intestinalis and Heliotropium sp. crude extracts as possible interfering agents on the Autophagocytosis pathway: Preliminary results Open
Bernardini S, Donoso-Fierro C, Tiezzi A, Tassoni M, Fava E, Becerra J, Perez C, Ovidi E. (2018). Evaluation of the effects of Ulva sp., Cryptomenia sp., Ciona intestinalis and Heliotropium sp. crude extracts as possible interfering agents …
View article: Alkaloids from Chilean species of the genus Rhodophiala C. Presl (Amaryllidaceae) and their chemotaxonomic importance
Alkaloids from Chilean species of the genus Rhodophiala C. Presl (Amaryllidaceae) and their chemotaxonomic importance Open
The family Amaryllidaceae is widely distributed from temperate to tropical regions. Amaryllidaceae species from the subfamily Amaryllidoideae can biosynthesize alkaloids with important physiological effects. Rhodophiala C. Presl is one of …
View article: Marine Longilenes, Oxasqualenoids with Ser-Thr Protein Phosphatase 2A Inhibition Activity
Marine Longilenes, Oxasqualenoids with Ser-Thr Protein Phosphatase 2A Inhibition Activity Open
The red seaweed Laurencia viridis is a rich source of oxygenated secondary metabolites that were derived from squalene. We report here the structures of three novel compounds, (+)-longilene peroxide (1), longilene (2), and (+)-prelongilene…
View article: A Natural Benzofuran from the Patagonic <i>Aleurodiscus vitellinus</i> Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-β Peptide Toxicity
A Natural Benzofuran from the Patagonic <i>Aleurodiscus vitellinus</i> Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-β Peptide Toxicity Open
Alzheimer’s disease (AD) is characterized by amyloid plaques that form due to an increase in amyloid-β peptide (Aβ) aggregation. One strategy in the search of new treatments for AD focuses on compounds that decrease Aβ accumulation. Compou…
View article: CHANGES IN SECONDARY METABOLITES PROFILES AND BIOLOGICAL ACTIVITY OF THE FRESH FRUITING BODIES OF Stereum hirsutum EXPOSED TO HIGH-DOSE UV-B RADIATION
CHANGES IN SECONDARY METABOLITES PROFILES AND BIOLOGICAL ACTIVITY OF THE FRESH FRUITING BODIES OF Stereum hirsutum EXPOSED TO HIGH-DOSE UV-B RADIATION Open
The present study aims to investigate the effects of ultraviolet radiation (type B) on the steroid and fatty acids content, phenolic compounds and biological activities of Stereum hirsutum wild fruiting bodies, which has been used by both …
View article: Steroidal composition and cytotoxic activity from fruiting body of <i>Cortinarius xiphidipus</i>
Steroidal composition and cytotoxic activity from fruiting body of <i>Cortinarius xiphidipus</i> Open
From the fruiting body of ectomycorrhizal fungi Cortinarius xiphidipus, sterols were identified from the crude extract and the cytotoxic effect of ergosta-4, 6, 8(14), 22-tetraen-3-one (ergone) was evaluated. Ten sterols including ergosta-…