Padma Kaul
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View article: Peripartum Outcomes and Safe Disease-Specific Medication Use Remain Suboptimal in Women with Immune-Mediated Inflammatory Diseases
Peripartum Outcomes and Safe Disease-Specific Medication Use Remain Suboptimal in Women with Immune-Mediated Inflammatory Diseases Open
Objectives Observational and population levels studies confirm that immune-mediated inflammatory diseases (IMIDs) including rheumatoid (RA) and psoriatic (PsA) arthritis, spondyloarthritis (SpA) and systemic lupus erythematous (SLE) can ne…
View article: Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With 3‐Vessel Coronary Artery Disease and Diabetes
Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With 3‐Vessel Coronary Artery Disease and Diabetes Open
Background Coronary artery bypass grafting (CABG) has been associated with reduced mortality, myocardial infarction, and repeat revascularization compared with percutaneous coronary intervention (PCI) for patients with 3‐vessel coronary ar…
View article: SUBOPTIMAL MEDICATION USE AND WORSE PERIPARTUM OUTCOMES IN WOMEN WITH LUPUS COMPARED TO THE GENERAL POPULATION
SUBOPTIMAL MEDICATION USE AND WORSE PERIPARTUM OUTCOMES IN WOMEN WITH LUPUS COMPARED TO THE GENERAL POPULATION Open
O064 / #405 Topic: AS21 - Pregnancy and Reproductive Health ABSTRACT CONCURRENT SESSION 11: PREGNANCY IN SLE 24-05-2025 10:40 AM - 11:40 AM Background/Purpose Observational and population levels studies confirm that systemic lupus erythema…
View article: Outcomes and Patterns Related to Magnesium in Acute Heart Failure: A Population-Based Study
Outcomes and Patterns Related to Magnesium in Acute Heart Failure: A Population-Based Study Open
Importance The significance of magnesium as a treatment or prognostic factor is unknown in heart failure despite its frequent use. Objective To assess the frequency and outcomes of magnesium testing, hypomagnesemia and intravenous (IV) rep…
View article: Hyperkalemia-related Heart Failure Therapy Discontinuation and the Association with Outcomes in Patients with Heart Failure
Hyperkalemia-related Heart Failure Therapy Discontinuation and the Association with Outcomes in Patients with Heart Failure Open
Background Renin-angiotensin-aldosterone system (RAAS) inhibitors are essential treatments for heart failure (HF) patients, but their use is often limited by hyperkalemia. Objective This study assesses the incidence of hyperkalemia in chro…
View article: Impact of Baseline Kidney Function on the Rate of Progressive Kidney Disease After Pregnancy: A Population-Based Cohort Study Research Protocol
Impact of Baseline Kidney Function on the Rate of Progressive Kidney Disease After Pregnancy: A Population-Based Cohort Study Research Protocol Open
Background: Better data are necessary to determine whether baseline level of kidney function affects the rate of progressive kidney disease following pregnancy. Objective: The objective was to determine whether the baseline (pre-pregnancy)…
View article: Medications used among Non-Hospitalized Pregnant Women with COVID-19: a Prospective Individual Patient Data Meta-analysis in Europe and North America
Medications used among Non-Hospitalized Pregnant Women with COVID-19: a Prospective Individual Patient Data Meta-analysis in Europe and North America Open
Aim To estimate the prevalence of medication use in non-hospitalized pregnant women with COVID-19 Methods A prospective two-stage individual patient meta-analysis across 10 data sources in Europe and North America studied medication use am…
View article: Predicting COVID-19 Outcomes Among Albertans With Diabetes and COVID-19: A Machine Learning Approach
Predicting COVID-19 Outcomes Among Albertans With Diabetes and COVID-19: A Machine Learning Approach Open
Background: Certain patients with diabetes and COVID-19 are at high risk of severe outcomes. Identification of risk factors among this group is required to risk-stratify those who may benefit from further surveillance. We aimed to develop …
View article: Long-term outcomes of catheter ablation compared with medical therapy in atrial fibrillation
Long-term outcomes of catheter ablation compared with medical therapy in atrial fibrillation Open
In this cohort study, patients who received CA demonstrated a reduction in the risk of long-term adverse cardiovascular outcomes compared with medical therapy in patients with AF, providing some data to indicate the effects of CA in the lo…
View article: A Study on the Evaluation of the Prevalence of Coronary Artery Disease and Its Associated Risk Factors among Rural and Urban Population
A Study on the Evaluation of the Prevalence of Coronary Artery Disease and Its Associated Risk Factors among Rural and Urban Population Open
Coronary artery disease (CAD) is a major global health concern, with varying prevalence and risk factors between rural and urban populations. Urban areas face a higher burden due to sedentary lifestyles, unhealthy diets, obesity, diabetes,…
View article: Economic Burden of Heart Failure Hospitalizations in Canada: A Population-based Study
Economic Burden of Heart Failure Hospitalizations in Canada: A Population-based Study Open
HF places a substantial economic burden on the Canadian health care system, which is likely to increase in the coming decades. Health system planning and policy solutions to identify, and reduce barriers to, HF therapies that are effective…
View article: Trends of antiseizure medication utilization among pregnant people in four Canadian provinces from 1998 to 2023; a study from the Canadian mother-child cohort active surveillance initiative (CAMCCO)
Trends of antiseizure medication utilization among pregnant people in four Canadian provinces from 1998 to 2023; a study from the Canadian mother-child cohort active surveillance initiative (CAMCCO) Open
Background Epilepsy management during pregnancy is crucial for both the mother and fetus. The use of antiseizure medications (ASMs) during pregnancy requires careful consideration due to their potential effects on maternal and fetal health…
View article: Impact of Remoteness of Residence and Socioeconomic Status on Outcomes Among Children With Heart Disease in Alberta
Impact of Remoteness of Residence and Socioeconomic Status on Outcomes Among Children With Heart Disease in Alberta Open
Age at diagnosis, time to intervention, annual primary care visits, and transplant-free all-cause survival were not impacted by RoR or SES in children with heart disease. Greater RoR and SES, however, were associated with fewer annual card…
View article: Machine Learning For Risk Prediction After Heart Failure Emergency Department Visit or Hospital Admission Using Administrative Health Data
Machine Learning For Risk Prediction After Heart Failure Emergency Department Visit or Hospital Admission Using Administrative Health Data Open
Aims Patients visiting the emergency department (ED) or hospitalized for heart failure (HF) are at increased risk for subsequent adverse outcomes, however effective risk stratification remains challenging. We utilized a machine-learning (M…
View article: IMPACT OF THE COVID-19 PANDEMIC ON ADHERENCE TO CARDIOVASCULAR MEDICATIONS AMONG CHRONICALLY TREATED PATIENTS IN ALBERTA
IMPACT OF THE COVID-19 PANDEMIC ON ADHERENCE TO CARDIOVASCULAR MEDICATIONS AMONG CHRONICALLY TREATED PATIENTS IN ALBERTA Open
Background: Some studies have suggested that the COVID-19 pandemic negatively impacted patient adherence with chronic therapies. We designed this study to explore whether cardiovascular drug adherence patterns changed in chronically treate…
View article: Premature Acute Myocardial Infarction Treated With Invasive Revascularization: Comparing STEMI With NSTEMI in a Population-Based Study of Young Patients
Premature Acute Myocardial Infarction Treated With Invasive Revascularization: Comparing STEMI With NSTEMI in a Population-Based Study of Young Patients Open
In young patients with AMI, STEMI was a disproportionately male phenomenon and associated with higher mortality at index hospitalization. One-year and 5-year outcomes were similar among STEMI and NSTEMI patients in those discharged alive a…
View article: Outrunning the grim reaper: longevity of the first 200 sub-4 min mile male runners
Outrunning the grim reaper: longevity of the first 200 sub-4 min mile male runners Open
Objectives To determine the impact of running a sub-4 min mile on longevity. It was hypothesised that there would be an increase in longevity for runners who successfully completed a sub-4 min mile compared with the general population. Met…
View article: Federated Learning and Differential Privacy Techniques on Multi-hospital Population-scale Electrocardiogram Data
Federated Learning and Differential Privacy Techniques on Multi-hospital Population-scale Electrocardiogram Data Open
This research paper explores ways to apply Federated Learning (FL) and Differential Privacy (DP) techniques to population-scale Electrocardiogram (ECG) data. The study learns a multi-label ECG classification model using FL and DP based on …
View article: Association Between Hemoglobin A1c and Development of Cardiovascular Disease in Canadian Men and Women Without Diabetes at Baseline: A Population‐Based Study of 608 474 Adults
Association Between Hemoglobin A1c and Development of Cardiovascular Disease in Canadian Men and Women Without Diabetes at Baseline: A Population‐Based Study of 608 474 Adults Open
Background We examined the association between hemoglobin A1c (HbA1c) and the development of cardiovascular disease (CVD) in men and women, without diabetes or CVD at baseline. Methods and Results This retrospective cohort study included a…
View article: Canadian Cost-Effectiveness of Coronary Artery Calcium Screening Based on the Multi-Ethnic Study of Atherosclerosis
Canadian Cost-Effectiveness of Coronary Artery Calcium Screening Based on the Multi-Ethnic Study of Atherosclerosis Open
CAC score-guided statin initiation in comparison to universal statin treatment was borderline cost-neutral at 5 years and cost-effective at 10 years in statin-eligible Canadian patients at intermediate cardiovascular disease risk.
View article: Predicting Individual Survival Distributions Using ECG: A Deep Learning Approach Utilizing Features Extracted by a Learned Diagnostic Model
Predicting Individual Survival Distributions Using ECG: A Deep Learning Approach Utilizing Features Extracted by a Learned Diagnostic Model Open
In the field of healthcare, individual survival prediction is important for personalized treatment planning. This study presents machine learning algorithms for predicting Individual Survival Distributions (ISD) using electrocardiography (…