Stefan Parent
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View article: Effect of Vertebral Body Tether Tensioning on Vertebral Body Growth Modulation
Effect of Vertebral Body Tether Tensioning on Vertebral Body Growth Modulation Open
Background The relationship between tether tension and spinal growth modulation following vertebral body tethering (VBT) has not been studied in growing children. Aims This study aims to explore the relationship between vertebral body grow…
View article: My orthopedic brace inventory (MOBI): a new, reliable, and valid questionnaire to identify barriers to brace adherence in adolescent idiopathic scoliosis treatment
My orthopedic brace inventory (MOBI): a new, reliable, and valid questionnaire to identify barriers to brace adherence in adolescent idiopathic scoliosis treatment Open
Purpose Full-time wearing of an orthopedic brace has demonstrated effectiveness in limiting curve progression in adolescents with idiopathic scoliosis. However, treatment adherence is challenging, with an average wearing time of 13 h/day. …
View article: 3D Sagittal Parameters Can Guide the Indications for Anterior Release in Thoracic AIS ≥70°
3D Sagittal Parameters Can Guide the Indications for Anterior Release in Thoracic AIS ≥70° Open
Study Design Retrospective, multicenter. Objectives This study aims to evaluate the immediate postoperative effect of, and define indications for, an anterior release (discectomy) in large AIS curves utilizing 3D deformity analysis. Method…
View article: Automatic Evaluation of Bone Age Using Hand Radiographs and Pancorporal Radiographs in Adolescent Idiopathic Scoliosis
Automatic Evaluation of Bone Age Using Hand Radiographs and Pancorporal Radiographs in Adolescent Idiopathic Scoliosis Open
Background/Objectives: Adolescent idiopathic scoliosis (AIS) is a complex, three-dimensional spinal deformity that requires monitoring of skeletal maturity for effective management. Accurate bone age assessment is important for evaluating …
View article: Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology
Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology Open
Adolescent Idiopathic Scoliosis (AIS) is the most common orthopedic condition requiring surgery, affecting 4% of adolescents. There is currently no proven method or prognostic test to identify symptomatic patients at risk of developing sev…
View article: Prediction of the upright articulated spine shape in the operating room using conditioned neural kernel fields
Prediction of the upright articulated spine shape in the operating room using conditioned neural kernel fields Open
Anterior vertebral tethering (AVT) is a non-invasive spine surgery technique, treating severe spine deformations and preserving lower back mobility. However, patient positioning and surgical strategies greatly influences postoperative resu…
View article: Growth modulation response in vertebral body tethering depends primarily on magnitude of concave vertebral body growth
Growth modulation response in vertebral body tethering depends primarily on magnitude of concave vertebral body growth Open
Purpose There is variability in clinical outcomes with vertebral body tethering (VBT) partly due to a limited understanding of the growth modulation (GM) response. We used the largest sample of patients with 3D spine reconstructions to cha…
View article: Association between the GLP1R A316T Mutation and Adolescent Idiopathic Scoliosis in French Canadian and Italian Cohorts
Association between the GLP1R A316T Mutation and Adolescent Idiopathic Scoliosis in French Canadian and Italian Cohorts Open
Studies have revealed anthropometric discrepancies in girls with adolescent idiopathic scoliosis (AIS) compared to non-scoliotic subjects, such as a higher stature, lower weight, and lower body mass index. While the causes are still unknow…
View article: Ovine model of congenital chest wall and spine deformity: From birth to 3 months follow‐up
Ovine model of congenital chest wall and spine deformity: From birth to 3 months follow‐up Open
Background The evolution and treatment of lung alterations related to congenital spine and chest wall deformities (CWD) are poorly understood. Most animal models of CWD created postnatally were not evaluated for respiratory function. The g…
View article: Differential Regulation of POC5 by ERα in Human Normal and Scoliotic Cells
Differential Regulation of POC5 by ERα in Human Normal and Scoliotic Cells Open
Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional spinal deformity. The incidence of AIS in females is 8.4 times higher than in males. Several hypotheses on the role of estrogen have been postulated for the progression o…
View article: Concave and convex growth do not differ over tethered vertebral segments, even with open tri-radiate cartilage
Concave and convex growth do not differ over tethered vertebral segments, even with open tri-radiate cartilage Open
Purpose To assess the following hypotheses related to vertebral body tethering (VBT): 1. VBT is associated with asymmetric (concave > convex) increases in height over the instrumented vertebra. 2. The instrumented Cobb angle improves follo…
View article: UNIVERSITY OF MONTREAL’S CLINICIAN-INVESTIGATOR PROGRAM: A 10-YEAR DESCRIPTIVE EVALUATION
UNIVERSITY OF MONTREAL’S CLINICIAN-INVESTIGATOR PROGRAM: A 10-YEAR DESCRIPTIVE EVALUATION Open
Purpose Clinician-investigators have an important role in the development and implantation of new therapies and treatment modalities; however, there have been several reports highlighting a pending shortage in the clinician-investigators’ …
View article: Circulatory Adipokines and Incretins in Adolescent Idiopathic Scoliosis: A Pilot Study
Circulatory Adipokines and Incretins in Adolescent Idiopathic Scoliosis: A Pilot Study Open
Adolescent idiopathic scoliosis (AIS) is a three-dimensional malformation of the spine of unknown cause that develops between 10 and 18 years old and affects 2–3% of adolescents, mostly girls. It has been reported that girls with AIS have …
View article: A Dangerous Curve: Impact of the COVID-19 Pandemic on Brace Treatment in Adolescent Idiopathic Scoliosis
A Dangerous Curve: Impact of the COVID-19 Pandemic on Brace Treatment in Adolescent Idiopathic Scoliosis Open
Study Design Observational Cohort study. Objectives We aim to document the abandon and irregular compliance rate towards brace treatment during the COVID-19 pandemic and its impact on AIS progression. Methods We reviewed a database of AIS …
View article: Thoracic Curve Correction Ratio: An Objective Measure to Guide against Overcorrection of a Main Thoracic Curve in the Setting of a Structural Proximal Thoracic Curve
Thoracic Curve Correction Ratio: An Objective Measure to Guide against Overcorrection of a Main Thoracic Curve in the Setting of a Structural Proximal Thoracic Curve Open
Purpose: The correction of double thoracic (Lenke 2) curves has been associated with higher rates of postoperative shoulder imbalance that may compromise long-term outcomes following spinal deformity correction. A number of methods have be…
View article: Prevalence of POC5 Coding Variants in French-Canadian and British AIS Cohort
Prevalence of POC5 Coding Variants in French-Canadian and British AIS Cohort Open
Adolescent idiopathic scoliosis (AIS) is a complex common disorder of multifactorial etiology defined by a deviation of the spine in three dimensions that affects approximately 2% to 4% of adolescents. Risk factors include other affected f…
View article: Anterior Vertebral Body Tethering for Treatment of Idiopathic Scoliosis in the Skeletally Immature
Anterior Vertebral Body Tethering for Treatment of Idiopathic Scoliosis in the Skeletally Immature Open
Study Design. Prospective case series. Objective. Determine the efficacy of anterior vertebral body tethering (AVBT) in skeletally immature patients. Summary of Background Data. The value of AVBT is currently unclear given the paucity of a…