Patrizia Burra
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View article: Machine Learning Identifies a Distinct Microbiota Signature in Immune Checkpoint Inhibitor Colitis Compared with Inflammatory Bowel Disease
Machine Learning Identifies a Distinct Microbiota Signature in Immune Checkpoint Inhibitor Colitis Compared with Inflammatory Bowel Disease Open
Background Immune checkpoint inhibitors (ICIs) have revolutionized oncology by enhancing anti-tumor immune responses. However, their use is frequently associated with immune-mediated adverse events, including colitis (ICIs-colitis). This c…
View article: Recompensation after acute decompensation in alcohol-related cirrhosis is rare and likely unrelated to platelet-poor plasma thrombin generation and fibrinolysis
Recompensation after acute decompensation in alcohol-related cirrhosis is rare and likely unrelated to platelet-poor plasma thrombin generation and fibrinolysis Open
In acutely decompensated, alcohol-related cirrhosis, recompensation is rare and linked to the baseline severity of liver disease. Coagulation and fibrinolysis seem not to be involved in cirrhosis recompensation.
View article: From comics to care: exploring the education potential of graphic novel in organ transplantation journey
From comics to care: exploring the education potential of graphic novel in organ transplantation journey Open
Organ transplantation profoundly enhances survival and quality of life for patients with end-stage organ failure but presents challenges such as lifelong immunosuppression, complications and psychosocial stress. The graphic novel I nuovi n…
View article: Transition From Youth to Adulthood: UEG 2024 Roundtable on Navigating Chronic Digestive and Liver Disease Care
Transition From Youth to Adulthood: UEG 2024 Roundtable on Navigating Chronic Digestive and Liver Disease Care Open
View article: Association Between Sustained Virological Response and Adverse Liver-related Events in Patients With Decompensated Hepatitis C Virus Cirrhosis
Association Between Sustained Virological Response and Adverse Liver-related Events in Patients With Decompensated Hepatitis C Virus Cirrhosis Open
SVR was associated with a reduced risk of LREs in patients with decompensated HCV cirrhosis with a MELD score <15, whereas no clinical benefit was observed in those with higher MELD scores despite an SVR-associated MELD decrease.
View article: Running towards liver transplantation
Running towards liver transplantation Open
View article: Decline in Complications and Mortality in Chronic Liver Disease and Cirrhosis: A Population‐Based Cohort Study From Northeastern Italy
Decline in Complications and Mortality in Chronic Liver Disease and Cirrhosis: A Population‐Based Cohort Study From Northeastern Italy Open
Background Current trends in complications and mortality among individuals with chronic liver disease and cirrhosis are largely unknown. Objective To explore changes in mortality trends among patients with cirrhosis and chronic liver disea…
View article: LRF Optimization
LRF Optimization Open
For high-quality steel ladle refining furnace is necessary for temperature, deoxidization, desulphurization, and inclusion removal as well as for fine-tuning composition of molten steel grades such as bearing steel where fatigue life is gr…
View article: Forecasting Apparel Sales Using Time Series Models and Machine Learning Techniques for Cost-Effective Procurement
Forecasting Apparel Sales Using Time Series Models and Machine Learning Techniques for Cost-Effective Procurement Open
This research presents a comprehensive data-driven approach to apparel sales forecasting designed to address the critical inventory management challenges faced by multi-outlet retail businesses. The client operates numerous business outlet…
View article: Real-Time Multivariate Vital Sign Forecasting in Intensive Care Units: A Comparative Study of Machine Learning Models with Emphasis on Time Series Mixer for Early Warning Systems
Real-Time Multivariate Vital Sign Forecasting in Intensive Care Units: A Comparative Study of Machine Learning Models with Emphasis on Time Series Mixer for Early Warning Systems Open
Real-time monitoring and prediction of physiological parameters in critical care settings remains essential for preventing patient deterioration and enabling timely medical interventions. This research examines various computational approa…
View article: Pre-liver Transplant Functional Status: Refining Assessment and Outcomes for MASLD Patients
Pre-liver Transplant Functional Status: Refining Assessment and Outcomes for MASLD Patients Open
View article: Machine Learning-Based Pallet Optimization for Warehouse Efficiency: A Data-Driven Approach
Machine Learning-Based Pallet Optimization for Warehouse Efficiency: A Data-Driven Approach Open
Optimizing logistics cutting expenses and guaranteeing seamless supply chain operations all depend on effective warehouse inventory and pallet management this study addresses issues related to ineffective pallet stacking wrong weight distr…
View article: At the earliest: a Hub and Spoke referral and referral-back pilot project increases access to liver transplantation and ensures good long-term care
At the earliest: a Hub and Spoke referral and referral-back pilot project increases access to liver transplantation and ensures good long-term care Open
View article: Early Detection Of Hypertension Using Stacked Ensemble Learning with SMOTE And Feature Selection
Early Detection Of Hypertension Using Stacked Ensemble Learning with SMOTE And Feature Selection Open
Hypertension (HTN), or high blood pressure (BP), is a serious health condition that arises when BP levels remain consistently above normal. It is often linked to modern lifestyle changes and lack of regular physical activity. Early detecti…
View article: Pediatric Liver and Kidney Transplant Recipients Demonstrate Greater Serological Response to SARS-CoV-2 Vaccination Than Adults
Pediatric Liver and Kidney Transplant Recipients Demonstrate Greater Serological Response to SARS-CoV-2 Vaccination Than Adults Open
Background. Adult solid organ transplant recipients (SOTRs) have decreased responsiveness to severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) vaccination and higher incidence of infection, but there are few data on the ser…
View article: The impact of age and frailty on hospitalization and survival in older liver transplant recipients: a longitudinal cohort study
The impact of age and frailty on hospitalization and survival in older liver transplant recipients: a longitudinal cohort study Open
Purpose Frailty is a well-established risk factor for adverse outcomes, particularly in liver transplant candidates. This study investigates the impact of age and frailty on key clinical outcomes—hospitalizations, waitlist survival, and po…
View article: Sex differences in hepatic encephalopathy: addressing the knowledge gap
Sex differences in hepatic encephalopathy: addressing the knowledge gap Open
Hepatic encephalopathy (HE) is a brain dysfunction caused by liver insufficiency and/or portal-systemic shunting with a significant impact on patients' quality of life and healthcare systems. This narrative review was elaborated by the Spe…
View article: Intelligent Resource Optimization: Enhancing Component Reuse through AI-Driven Image Classification
Intelligent Resource Optimization: Enhancing Component Reuse through AI-Driven Image Classification Open
This paper presents an AI-powered system designed to automate the identification and cataloging of electric switchgear components, improving inventory management and minimizing errors caused by manual classification. Traditional identifica…
View article: Intelligent Resource Optimization: Enhancing Component Reuse through AI-Driven Image Classification
Intelligent Resource Optimization: Enhancing Component Reuse through AI-Driven Image Classification Open
This paper presents an AI-powered system designed to automate the identification and cataloging of electric switchgear components, improving inventory management and minimizing errors caused by manual classification. Traditional identifica…
View article: Global Consensus Recommendations for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis
Global Consensus Recommendations for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis Open
View article: The Growing Burden of Obesity: Addressing a Global Public Health Challenge
The Growing Burden of Obesity: Addressing a Global Public Health Challenge Open
View article: Hospital Dashboard Analytics: Enhancing Healthcare Performance with Data-Driven Insights
Hospital Dashboard Analytics: Enhancing Healthcare Performance with Data-Driven Insights Open
Many healthcare organizations face challenges with scattered data, inefficient use of resources, and difficulty in gaining useful insights. These issues affect hospital operations, patient care, and financial management. To solve this prob…
View article: Sexual health and function in liver disease
Sexual health and function in liver disease Open
Sex is a central aspect of human life and is significantly impacted by chronic illness. Cirrhosis, due to its unique pathophysiology and the side effects of common therapies, serves as a paradigmatic example, being associated with very hig…
View article: Protocol for an international multicenter, prospective, observational, non-competitive, study to validate and optimise prediction models of 90-day and 1-year allograft failure after liver transplantation: The global IMPROVEMENT Study
Protocol for an international multicenter, prospective, observational, non-competitive, study to validate and optimise prediction models of 90-day and 1-year allograft failure after liver transplantation: The global IMPROVEMENT Study Open
View article: Somatic Copy Number Alterations in Circulating Cell-Free DNA as a Prognostic Biomarker for Hepatocellular Carcinoma: Insights from a Proof-of-Concept Study
Somatic Copy Number Alterations in Circulating Cell-Free DNA as a Prognostic Biomarker for Hepatocellular Carcinoma: Insights from a Proof-of-Concept Study Open
Background/Objectives: Despite advances in hepatocellular carcinoma (HCC) management, prognosis remains poor. Advanced-stage diagnosis often excludes curative treatments, and current biomarkers (e.g., alpha-fetoprotein [AFP]) have limited …
View article: Limits of Systemic Treatments for HCC in Decompensated Patients
Limits of Systemic Treatments for HCC in Decompensated Patients Open
Hepatocellular carcinoma (HCC) in patients with decompensated cirrhosis presents significant treatment challenges due to the impaired liver function, altered pharmacokinetics, and systemic inflammation associated with advanced liver diseas…
View article: Chronic Hepatitis B in the Transplant Setting: A 30-Year Experience in a Single Tertiary Italian Center
Chronic Hepatitis B in the Transplant Setting: A 30-Year Experience in a Single Tertiary Italian Center Open
Background: Hepatitis B virus (HBV) remains a leading etiology for liver transplantation (LT). In a large cohort of HBsAg-positive patients, this study evaluates long-term patient and graft survival after LT over the past 30 years while an…
View article: Recurrence of autoimmune hepatitis cholestatic variant syndromes after liver transplantation affects graft and patient survival
Recurrence of autoimmune hepatitis cholestatic variant syndromes after liver transplantation affects graft and patient survival Open
View article: Sex-based disparities in liver transplantation: Evidence from a nationwide Italian cohort
Sex-based disparities in liver transplantation: Evidence from a nationwide Italian cohort Open
View article: Liver transplantation for hepatitis D virus/hepatitis B virus coinfection in Italy: An intention-to-treat analysis of long-term outcomes
Liver transplantation for hepatitis D virus/hepatitis B virus coinfection in Italy: An intention-to-treat analysis of long-term outcomes Open
Patients with hepatitis D virus (HDV)/hepatitis B virus (HBV)-related end-stage liver disease candidates for liver transplantation (LT) have traditionally been regarded as a special population, although their outcomes are controversial. An…