Ramakrishnan Parthasarathi
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Unveiling the hidden ring: A case report of unique presentation of internal hernia Open
Internal hernias are a rare cause of small-bowel obstruction (SBO), particularly in patients without prior abdominal surgery. This case report describes a 70-year-old male presenting with acute intestinal obstruction in a virgin abdomen. I…
Safety and feasibility of concomitant ventral hernia repair and total laparoscopic hysterectomy: A single-centre experience of over 1000 cases Open
Introduction: Laparoscopic ventral hernia surgery has become the standard of care for most surgeons, offering improved patient outcomes, shorter hospital stays, and fewer complications compared to open surgeries. However, the benefits of c…
View article: Protic or phosphate-based ionic liquids useful for lignocellulosic processing
Protic or phosphate-based ionic liquids useful for lignocellulosic processing Open
The present invention provides for novel protic ionic liquids (PIL) or phosphate-based ionic liquid (PBIL) useful for lignocellulosic processing described herein. The novel protic ionic liquids are capable of pretreatment of lignocellulosi…
Enhancing IT Service Management in Indian IT Organizations: A Technological Integration of ISO 20000 with AI, Blockchain, Predictive Analytics, and Zero Trust Security Open
The paper presents the research that describes the impact of implementing ISO 20000 in the Service Management System (SMS) in Indian IT organizations with an innovative approach to enhance its effectiveness based on emerging technologies. …
A case report and review of literature on idiopathic ascites after laparoscopic appendectomy - A surgeon’s dilemma Open
Acute appendicitis is one of the most common emergency surgical conditions, typically treated by laparoscopic appendectomy in most centres. Post-operative ascites is a rare complication after laparoscopic surgery, especially in the absence…
The Advantages of Adopting the ISO/IEC 17025: 2017 Lab Management System in Calibration and Testing Laboratories Open
International Organization for Standardization (ISO) and International Electrotechnical Commission (IEC) standards for testing and calibration laboratories are known as ISO/IEC17025:2017, which is the standard for laboratory certification.…
613. LAPAROSCOPIC MANAGEMENT OF TYPE IV HIATAL HERNIA WITH MESH AUGMENTATION CRUROPLASTY - EXPERIENCE AT A TERTIARY CARE CENTRE Open
Background Type IV para-esophageal hernias, which are characterized by herniation of other organs in addition to stomach, are rare - comprising only 2-5% of all para-esophageal hernias. They are associated with life-threatening complicatio…
View article: 515. LAPAROSCOPIC PHARYNGO-COLOPLASTY WITH RIGHT COLON FOR A CASE OF COROSSIVE INJURY
515. LAPAROSCOPIC PHARYNGO-COLOPLASTY WITH RIGHT COLON FOR A CASE OF COROSSIVE INJURY Open
Introduction Corrosive stricture of esophagus and stomach is more common in Acid poisoning. Management these cases requires good surgical planning, technical expertise in doing these complex procedures Case report A34 year gentleman consum…
487. A RARE CASE OF BRONCHOGENIC CYST ESOPHAGUS Open
Introduction Bronchogenic cyst is a relatively rare congenital malformation that develops from abnormal budding of the ventral foregut during the early stage of gestation. Histologically, the cyst wall is covered by respiratory-type ciliat…
View article: 806. MINIMALLY INVASIVE REVISION FUNDOPLICATION, IS IT SAFE AND FEASIBLE? SINGLE CENTER EXPERIENCE
806. MINIMALLY INVASIVE REVISION FUNDOPLICATION, IS IT SAFE AND FEASIBLE? SINGLE CENTER EXPERIENCE Open
Introduction Laparoscopic fundoplication has become standard of care for patients with refractory gastroesophageal reflux disease, large and symptomatic hiatal hernia. Failure rate for laparoscopic fundoplication was between 2 to 17%. Doin…
Laparoscopic totally extraperitoneal management of giant inguinoscrotal hernia with loss of domain Open
A giant inguinoscrotal hernia extends below the level of the midpoint of the thigh, in an upright position. They are usually due to the neglect of the patient and fear of surgical intervention. Patients typically present with lower urinary…
View article: Temporal analysis and comparative genomic study of SARS-CoV-2 variants across Uttar Pradesh, India: Insights from the first and second COVID-19 waves
Temporal analysis and comparative genomic study of SARS-CoV-2 variants across Uttar Pradesh, India: Insights from the first and second COVID-19 waves Open
The rapid emergence of genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after late 2020, lead to origin of the term “variant of concern” and became the prime issue for the health of the human populations acr…
View article: Ecotoxicological impacts of landfill sites: Towards risk assessment, mitigation policies and the role of artificial intelligence
Ecotoxicological impacts of landfill sites: Towards risk assessment, mitigation policies and the role of artificial intelligence Open
Waste disposal in landfills remains a global concern. Despite technological developments, landfill leachate poses a hazard to ecosystems and human health since it acts as a secondary reservoir for legacy and emerging pollutants. This study…
View article: Molecular Property Diagnostic Suite for COVID-19 (MPDSCOVID-19): an open-source disease-specific drug discovery portal
Molecular Property Diagnostic Suite for COVID-19 (MPDSCOVID-19): an open-source disease-specific drug discovery portal Open
Molecular Property Diagnostic Suite (MPDS) was conceived and developed as an open-source disease-specific web portal based on Galaxy. MPDSCOVID-19 was developed for COVID-19 as a one-stop solution for drug discovery research. Galaxy platfo…
Front Cover Open
The cover image is based on the Research Article Discovering Targeted Inhibitors for Escherichia coli Efflux Pump Fusion Proteins using Computational and Structure-Guided Approaches by Shweta Singh Chauhan et al., https://doi.org/10.1002/j…
Bac-EPIC: A web interface for developing novel efflux pump inhibitor compounds targeting Escherichia coli Open
Multidrug resistance (MDR) poses a severe threat to human health. The existence of efflux pumps primarily contributes to resistance in Gram-negative bacterial infections. Efflux pump inhibitors (EPIs) can potentially improve the efficacy o…
View article: Molecular Property Diagnostic Suite for COVID-19 (MPDS <sup>COVID-19</sup> ): An open access disease specific drug discovery portal
Molecular Property Diagnostic Suite for COVID-19 (MPDS <sup>COVID-19</sup> ): An open access disease specific drug discovery portal Open
Computational drug discovery is intrinsically interdisciplinary and has to deal with the multifarious factors which are often dependent on the type of disease. Molecular Property Diagnostic Suite (MPDS) is a Galaxy based web portal which w…
Efflux Pump-Binding 4(3-Aminocyclobutyl)Pyrimidin-2-Amines Are Colloidal Aggregators Open
Efflux pumps are a relevant factor in antimicrobial resistance. In E. coli, the tripartite efflux pump AcrAB-TolC removes a chemically diverse set of antibiotics from the bacterium. Therefore, small molecules interfering with efflux pump f…
The dual role of phytochemicals on SARS-CoV-2 inhibition by targeting host and viral proteins Open
The results revealed that the selected phytochemicals from Andrographis paniculata, Aconitum heterophyllum, Costus speciosus and Inula racemosa may have the capacity to act with prominent affinity towards the host and viral proteins. There…
Chemical Reactivity and Skin Sensitization Studies on a Series of Chloro- and Fluoropyrroles—A Computational Approach Open
Global density functional descriptors analysis on a series of chloro- and fluoropyrroles provide vital data concerning their overall biochemical activities. In this study, a comprehensive investigation is presented for a series of chloro- …
Laparoscopic posterior rectopexy for complete rectal prolapse Open
Background: Rectal prolapse is more common in elderly women worldwide, but in India, it predominantly occurs in young- and middle-aged males. While ventral mesh rectopexy is proposed as the preferred procedure in females, the debate on the…
Laparoscopic anterior resection Open
Purpose: Laparoscopic rectal surgery has moved from being experimental to getting established as a mainstream procedure. We aimed at analysing how rectal cancer surgery has evolved at our institute. Methods: A retrospective review of 1000 …