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View article: Role of N-glycosylation in structural stability and binding specificity of IL-1ra antagonist to it receptor: an efficient approach to engineer therapeutic proteins
Role of N-glycosylation in structural stability and binding specificity of IL-1ra antagonist to it receptor: an efficient approach to engineer therapeutic proteins Open
Interleukin-1 receptor antagonist (IL-1ra) is a vital anti-inflammatory molecule, acting as a decoy protein that competitively binds to Interleukin-1 receptors (IL-1RI and IL-1RII). The deregulation of IL-1 activity has been linked to auto…
View article: Socio Economic Profile of Goat Farmers in Kallakurichi District of Tamil Nadu, India
Socio Economic Profile of Goat Farmers in Kallakurichi District of Tamil Nadu, India Open
The present study aims to analyze the socio-economic profile of goat farmers in the Kallakurichi district of Tamil Nadu, a region where livestock rearing plays a pivotal role in rural livelihoods. Goat farming served as a significant regul…
View article: Bilateral maxillary and mandibular involvement of Langerhans cell histiocytosis: A rare case report
Bilateral maxillary and mandibular involvement of Langerhans cell histiocytosis: A rare case report Open
Langerhans cell histiocytosis (LCH) is an uncommon disease characterized by the clonal proliferation of Langerhans cells, which are specialized dendritic cells that play a role in the body’s immune response. The hallmark of LCH is an aberr…
View article: Bayesian Estimation of Heritability, Repeatability, and Genetic Correlations in Crossbred Jersey Cattle
Bayesian Estimation of Heritability, Repeatability, and Genetic Correlations in Crossbred Jersey Cattle Open
In animal breeding programs, estimating genetic parameters such as heritability, repeatability, and genetic correlation is crucial for assessing breeding value, forecasting genetic progress in selection programs, and improving breeding str…
View article: Probiotication of finger millet porridge for enhancing its function and safety
Probiotication of finger millet porridge for enhancing its function and safety Open
Finger millet porridge, a traditional lactic acid fermented drink prepared from the minor millet Eleusine coracana (L.) has many nutritional and health benefits. In this study, the finger millet porridge was prepared, and probioticated wit…
View article: Simple DNA extraction for museum beetle specimens to unlock genetic data from historical collections
Simple DNA extraction for museum beetle specimens to unlock genetic data from historical collections Open
Museum beetle specimens are valuable resources for genetic analyses; however, obtaining DNA from aged specimens remains challenging due to degradation, desiccation, and contamination. In this study, we present a simple, low-cost protocol f…
View article: Diagnostic accuracy of Gorelick 10 point scale in comparison to IMCI scale in identifying significant dehydration in South Indian children? - A prospective observational study
Diagnostic accuracy of Gorelick 10 point scale in comparison to IMCI scale in identifying significant dehydration in South Indian children? - A prospective observational study Open
A BSTRACT Background: Unavoidable cause of mortality among under 5 children in India is dehydration resulting from acute diarrhoeal diseases. In spite of various dehydration scales available across the world, the most commonly used dehydra…
View article: Description and Assessment of an Antimicrobial Substance from Marine Actinobacteria
Description and Assessment of an Antimicrobial Substance from Marine Actinobacteria Open
Streptomyces is thought to be the primary source of bacteria for the synthesis of bioactive substances, such as naturally occurring antibiotics. Finding and identifying the actinomycetes exhibiting antagonistic activity was the primary goa…
View article: Lasioptera sharma, a new species of gall midge (Diptera: Cecidomyiidae) feeding on Leea indica (Vitaceae) in India
Lasioptera sharma, a new species of gall midge (Diptera: Cecidomyiidae) feeding on Leea indica (Vitaceae) in India Open
A new species of gall midge associated with the leaves of Leea indica (Burm.fil.) Merr. (Vitaceae) is described and illustrated. Two species of Lasioptera have been reported from the plant genus Leea so far and the present species is the t…
View article: Unveiling UVB resilience in Oryza sativa L.: Integrative analysis of physiological, molecular and microRNA responses
Unveiling UVB resilience in Oryza sativa L.: Integrative analysis of physiological, molecular and microRNA responses Open
Rice is the staple food for more than half of the global population. It is cultivated in over 100 countries, and is predominant in Asia, which accounts for 90 % of the world's production. As the most crucial food crop globally, rice is sen…
View article: Metabolomic Profiling of Leptadenia reticulata: Unveiling Therapeutic Potential for Inflammatory Diseases through Network Pharmacology and Docking Studies
Metabolomic Profiling of Leptadenia reticulata: Unveiling Therapeutic Potential for Inflammatory Diseases through Network Pharmacology and Docking Studies Open
Medicinal plants have been utilized since ancient times for their therapeutic properties, offering potential solutions for various ailments, including epidemics. Among these, Leptadenia reticulata, a member of the Asclepiadaceae family, ha…
View article: Homology modeling and protein-protein interaction studies of GAPDH from Helopeltis theivora and chitinase from Pseudomonas fluorescens to control infection in tea [Camellia sinensis (L.) O. Kuntze] plants
Homology modeling and protein-protein interaction studies of GAPDH from Helopeltis theivora and chitinase from Pseudomonas fluorescens to control infection in tea [Camellia sinensis (L.) O. Kuntze] plants Open
Tea [Camellia sinensis (L.) O. Kuntze] is an important crop cultivated in all over the world. The main problem in tea cultivation is the attack by a bug called Helopeltis theivora. Many different strategies, such as the use of pesticides a…
View article: Graft Dysfunction Due to Acute Interstitial Nephritis in the Immediate Posttransplant Period
Graft Dysfunction Due to Acute Interstitial Nephritis in the Immediate Posttransplant Period Open
Dear Editor, We are writing to share a compelling case of graft dysfunction caused by acute interstitial nephritis (AIN). AIN is characterized by histological findings of interstitial inflammatory cellular infiltrates, a variable degree of…
View article: Hecogenin a Plant Derived Small Molecule as an Antagonist to BACE-1: A Potential Target for Neurodegenerative Disorders
Hecogenin a Plant Derived Small Molecule as an Antagonist to BACE-1: A Potential Target for Neurodegenerative Disorders Open
The field of drug discovery has recognized the significance of computer-aided drug design. Recent advancements in structure identification and characterization, bio-computational science and molecular biology have significantly contributed…
View article: Isolation and cloning of the Pseudomonas fluorescens chitinase gene – An ecofriendly approach for its use as a specific biopesticide
Isolation and cloning of the Pseudomonas fluorescens chitinase gene – An ecofriendly approach for its use as a specific biopesticide Open
Efficacy of Agave sisalana n-Hexane Extract in the Control of Callosobruchus maculatus (Fabricius) (Colloptera: Bruchidae) PestChrinius Hammuel, Musa Mohammed, Olalekan Babatunde Adesina, Usman Jajere Mohammed, Eprhaim Akuaden Audu, Suleim…
View article: Role of DREB genes in the regulation of salt stress-mediated defense responses in plants
Role of DREB genes in the regulation of salt stress-mediated defense responses in plants Open
Abiotic stress plays a major role in plant growth and its development, multiple stress elements such as drought, cold, elevated temperature, and heavy metal contamination may influence them. However, salinity is still a universal abiotic s…
View article: A method for DNA extraction and molecular identification of Aphids
A method for DNA extraction and molecular identification of Aphids Open
View article: Emerging and reemerging viral diseases: Developments and future perspectives of plant-based vaccines
Emerging and reemerging viral diseases: Developments and future perspectives of plant-based vaccines Open
The reemergence of human infectious viruses such as SARS-CoV2, influenza and monkeypox are considered as a huge threat to mankind and vaccine development is the only preventive strategy available against these viral diseases. However, the …
View article: Integrated Metabolite and Transcriptome Profiling-Mediated Gene Mining of Sida cordifolia Reveals Medicinally Important Genes
Integrated Metabolite and Transcriptome Profiling-Mediated Gene Mining of Sida cordifolia Reveals Medicinally Important Genes Open
Sida cordifolia is a medicinal shrub that is conventionally used in the Indian system of medicine;however, the genes contributing to its medicinal properties have been minimally explored, thus limiting its application. High-throughputseque…
View article: De novo transcriptome analysis of Justicia adhatoda reveals candidate genes involved in major biosynthetic pathway
De novo transcriptome analysis of Justicia adhatoda reveals candidate genes involved in major biosynthetic pathway Open
View article: Molecular identification of scale insect (Eulecanium giganteum) in Hibiscus rosa-sinensis
Molecular identification of scale insect (Eulecanium giganteum) in Hibiscus rosa-sinensis Open
Hibiscus rosa-sinensis is a widely grown evergreen valuable medicinal, ornamental species planted in India. Scale insects are small herbivorous insects found on all continents and they are serious sap sucking pests of many ornamental plant…
View article: Thidiazuron, a phenyl-urea cytokinin, inhibits ergosterol synthesis and attenuates biofilm formation of Candida albicans
Thidiazuron, a phenyl-urea cytokinin, inhibits ergosterol synthesis and attenuates biofilm formation of Candida albicans Open
Candida albicans is a common human fungal pathogen that colonizes mucosa and develops biofilm in the oral cavity which cause oral candidiosis. This study investigates the effects of a new molecule thidiazuron against the growth and biofilm…
View article: De novo transcriptome analysis of Justicia adhatoda reveals candidate genes involved in major biosynthetic pathway
De novo transcriptome analysis of Justicia adhatoda reveals candidate genes involved in major biosynthetic pathway Open
BackgroundJusticia adhatoda is an important medicinal plant traditionally used in the Indian system of medicine and the absence of molecular-level studies on this plant hinders its wide use, hence the study was aimed to analyse the genes i…
View article: BIOPROSPECTING OF HALOPHILIC BACTERIA FROM THE COASTAL AREA OF MARAKANAM SALTPAN
BIOPROSPECTING OF HALOPHILIC BACTERIA FROM THE COASTAL AREA OF MARAKANAM SALTPAN Open
The saltpan is the resource of cultivating halophilic microbes for their produce diverse metabolites.This study was characterized a total of sixteen halophilic bacteria from Marakanam Saltpan, Tamilnadu, India.Amongthis isolate only Six is…
View article: Thidiazuron, a phenyl-urea cytokinin, inhibits ergosterol synthesis and attenuates biofilm formation of Candida albicans
Thidiazuron, a phenyl-urea cytokinin, inhibits ergosterol synthesis and attenuates biofilm formation of Candida albicans Open
Candida albicans is a commensal human fungal pathogen that colonizes and develops dental biofilm which cause Oral candidiosis. This study investigates the effects of a new molecule Thidiazuron against the growth and biofilm formation prope…
View article: The complete chloroplast genome of<i>Ocimum tenuiflorum</i>L. subtype Krishna Tulsi and its phylogenetic analysis
The complete chloroplast genome of<i>Ocimum tenuiflorum</i>L. subtype Krishna Tulsi and its phylogenetic analysis Open
The complete chloroplast genome (cp) of Ocimum tenuiflorum L. subtype Krishna Tulsi was sequenced and assembled using Illumina paired-end sequencing data. The cp genome is 151,758 bp in length, including a large single copy (LSC) re…
View article: A cross-sectional study of the prevalence of overweight and obesity amongst primary school children in Puducherry
A cross-sectional study of the prevalence of overweight and obesity amongst primary school children in Puducherry Open
Background: Globally, there is a steep escalation in the prevalence rates of overweight and obesity. Obesity during childhood is known to be related to diabetes, cancer and cardiovascular disease in adulthoodObjective: To assess prevalence…
View article: CHITINASE PRODUCING ENDOPHYTIC BACTERIA FROM Calotropis gigantea: A PROMISING PERSPECTIVE OF BIOPESTICIDE
CHITINASE PRODUCING ENDOPHYTIC BACTERIA FROM Calotropis gigantea: A PROMISING PERSPECTIVE OF BIOPESTICIDE Open
International audience
View article: First report of mango leaf gall midge Procontarinia robusta Li, Bu & Zhang (Diptera: Cecidomyiidae) from India
First report of mango leaf gall midge Procontarinia robusta Li, Bu & Zhang (Diptera: Cecidomyiidae) from India Open
The present study reports a leaf gall midge, Procontarinia robusta Li, Bu & Zhang of Mango, Mangifera indica L. from India. It is being reported for the first time from India. Earlier, this species was reported from China, Indonesia and Ea…
View article: Comparative bioefficacy of Bacillus and Pseudomonas chitinase against Helopeltis theivora in tea (Camellia sinensis (L.) O.Kuntze
Comparative bioefficacy of Bacillus and Pseudomonas chitinase against Helopeltis theivora in tea (Camellia sinensis (L.) O.Kuntze Open