P. V. Peretyagin
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View article: Evaluation of the Effectiveness and Safety of New Wound Coatings Based on Cod Collagen for Fast Healing of Burn Surfaces
Evaluation of the Effectiveness and Safety of New Wound Coatings Based on Cod Collagen for Fast Healing of Burn Surfaces Open
Wound coatings in the form of sponge plates were obtained based on hydrogels of cod collagen (CC) copolymers. The synthesis of CC copolymers with pectin was carried out in the presence of a triethylbor–hexamethylenediamine (TEB-HMDA) compl…
View article: Features of Anesthesia of Small and Large Laboratory Animals
Features of Anesthesia of Small and Large Laboratory Animals Open
In world practice, conducting biological, pharmacological, medical, and a number of other studies is often impossible without animal experiments. According to the provisions of the “European Convention for the Protection of Vertebrate Anim…
View article: Pharmaceutical composition of 1,2,4-trioxolanes with betulin in fish oil. Effect on oxidative and energy metabolism in the treatment of burns in rats
Pharmaceutical composition of 1,2,4-trioxolanes with betulin in fish oil. Effect on oxidative and energy metabolism in the treatment of burns in rats Open
Background. Ozonation products of unsaturated fatty acids in fats and oils – 1,2,4-trioxolanes – which contribute to the normalization of oxidative and energy metabolism in various diseases, may be a promising substance for the creation of…
View article: Diagnosis of Skin Burn-Induced Colon Circulatory Disorders Using Optical Coherence Tomography Angiography and Laser Doppler Flowmetry (Experimental Study)
Diagnosis of Skin Burn-Induced Colon Circulatory Disorders Using Optical Coherence Tomography Angiography and Laser Doppler Flowmetry (Experimental Study) Open
The OCTA and LDF methods allowed us to establish experimentally that during the first 45 min thermal burn causes considerable disturbances of the blood flow in the colon wall, which normalizes only by day 14 if no therapy is administered. …
View article: Comparison of the Effectiveness of Methods for Obtaining and Application the Stromal-Vascular Fraction of Adipose Tissue in an Experimental Model of a Donor Wound in Burns
Comparison of the Effectiveness of Methods for Obtaining and Application the Stromal-Vascular Fraction of Adipose Tissue in an Experimental Model of a Donor Wound in Burns Open
Introduction . The optimal method of obtaining and application a stromal-vascular fraction (SVF) of adipose tissue in the treatment of donor wounds in burned patients has not been determined. Objective — to compare the effectiveness of the…
View article: Examination of the Microvasculature During Wound Process of the Oral Mucosa when Using Dual-Wavelength Photodynamic Therapy: a Pre-Clinical Experimental Randomized Study
Examination of the Microvasculature During Wound Process of the Oral Mucosa when Using Dual-Wavelength Photodynamic Therapy: a Pre-Clinical Experimental Randomized Study Open
Background. Healing of open wounds in the oral cavity is often accompanied by infection and constant traumatization, which lead to impaired blood supply to the tissues, lack of trophic support and low oxygen supply to increasing proliferat…
View article: Photobiomodulation for Correction of Systemic Disorders of Experimental Pain Syndromes
Photobiomodulation for Correction of Systemic Disorders of Experimental Pain Syndromes Open
The development of anti-pain technologies in the complex treatment of pain syndromes is one of the most urgent tasks of modern medicine. We undertook a placebo-controlled experimental study of the therapeutic potential of low-intensity las…
View article: Photobiomodulation in Correction of Systemic Disorders of Experimental Pain Syndrome
Photobiomodulation in Correction of Systemic Disorders of Experimental Pain Syndrome Open
The development of anti-pain technologies in the complex treatment of pain syndromes is one of the most urgent tasks of modern medicine. We have undertaken a placebo-controlled experimental study of the therapeutic potential of low-intensi…
View article: Multimodal Optical Monitoring of Auto- and Allografts of Skin on a Burn Wound
Multimodal Optical Monitoring of Auto- and Allografts of Skin on a Burn Wound Open
The aim of the study was to investigate the dynamics of the state of allo- and autografts of skin on a wound using optical modalities: diffuse reflectance spectroscopy (DRS), optical coherence tomography (OCT), and laser Doppler flowmetry …
View article: Skin Micrograph Protector in a Burn Wound: Alloderm or Hydrogel Coating?
Skin Micrograph Protector in a Burn Wound: Alloderm or Hydrogel Coating? Open
AIM OF STUDY Was to compare the dynamics of engraftment of skin micrographs in a burn wound when using protectors from an allodermal graft and from a hydrogel coating. MATERIAL AND METHODS The experimental study was conducted on 18 rats wi…
View article: Study of the Effect of Low-Intensity Sub- and Millimeter Waves on the Induction of Adaptation Reactions in Experimental Burn
Study of the Effect of Low-Intensity Sub- and Millimeter Waves on the Induction of Adaptation Reactions in Experimental Burn Open
Burns are an actual problem of modern medicine. Oxidative stress, microcirculation, and hemostasis disorders are important links in the pathogenesis of burn disease. It is shown that these processes are significantly influenced by the poin…
View article: Experimental modeling of chemical burning of the esophagus using different concentrations of alkali solution
Experimental modeling of chemical burning of the esophagus using different concentrations of alkali solution Open
The purpose and objectives of the study: is to create an experimental model of a chemical burn of the esophagus with alkali to study the pathological transformation of the tissues of the upper gastrointestinal tract. Materials and methods.…
View article: The experience of polyhexanide usage as a part of wet environment in the treatment of limited burns
The experience of polyhexanide usage as a part of wet environment in the treatment of limited burns Open
INTRODUCTION. The results of the treatment of patients with restrictive burns I-II degrees are presented in the article. The OBJECTIVE of the research was to establish the efficiency of the usage of polyhexanide included in wet environment…
View article: Resonance Near-Field Microwave Probing as a Method for Exploration of Deep Burn Wound Structures in Experiment
Resonance Near-Field Microwave Probing as a Method for Exploration of Deep Burn Wound Structures in Experiment Open
The aim of the investigation was to study the diagnostic value of the near-field microwave probing in the assessment of the normal and experimentally burned rat skin profiles.Materials and Methods.The investigation was performed on 30 matu…
View article: The Usage of Laser Doppler Flowmetry for Evaluation of the Efficiency of Ozone-Containing Drugs for External Use
The Usage of Laser Doppler Flowmetry for Evaluation of the Efficiency of Ozone-Containing Drugs for External Use Open
Ozone-containing drugs for external use are the new trend in applying of medical ozone-oxygen mixture.For the last few years the majority of manufacturer countries have produced wide lines of ozone-containing cosmetics, which were presente…
View article: IN VITRO STUDY OF THE INFLUENCE OF VARIOUS CONCENTRATIONS OF DINITROSYL IRON COMPLEXES ON THE ACTIVITY OF ANTIOXIDANT ENZYMES IN THE BLOOD
IN VITRO STUDY OF THE INFLUENCE OF VARIOUS CONCENTRATIONS OF DINITROSYL IRON COMPLEXES ON THE ACTIVITY OF ANTIOXIDANT ENZYMES IN THE BLOOD Open
The effect of various concentrations of dinitrosyl iron complexes (DNICs) on the activity of superoxide dismutase (SOD), catalase and glutathione reductase (GR) was studied under in vitro conditions. The experiment was carried out using pr…