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View article: Adverse Events in Nonsurgical Facial Aesthetic Procedures: A Systematic Review and Meta‐Analysis
Adverse Events in Nonsurgical Facial Aesthetic Procedures: A Systematic Review and Meta‐Analysis Open
Objective To determine the prevalence and clinical profile of treatment‐related adverse events (TRAE) associated with: (1) botulinum toxin in the upper face; (2) hyaluronic acid fillers in the lower face and nasolabial folds; and (3) nonsu…
View article: A Clinicopathological Study of Marginal Gingival Leukoplakia
A Clinicopathological Study of Marginal Gingival Leukoplakia Open
Background Marginal gingival leukoplakias are relatively uncommon and rarely discussed in the scientific literature. Studies suggest they are distinct from other leukoplakias due to aggressive behavior and a strong association with prolife…
View article: Oral and Maxillofacial Pathology in Latin America and the Caribbean: A Comprehensive Survey of Recognition, Training, and Practice
Oral and Maxillofacial Pathology in Latin America and the Caribbean: A Comprehensive Survey of Recognition, Training, and Practice Open
Background Oral and maxillofacial pathology (OMFP) is a dental specialty that studies the causes, processes, and effects of diseases in the oral and maxillofacial area, while also contributing to diagnosis and treatment. Its recognition, t…
View article: Exploring the feasibility of AI-based analysis of histopathological variability in salivary gland tumours
Exploring the feasibility of AI-based analysis of histopathological variability in salivary gland tumours Open
This study uses artificial intelligence (AI) for differentiation between salivary gland tumours (SGT) using digitised Haematoxylin and Eosin stained whole-slide images (WSI). Machine learning (ML) classifiers were developed and tested usin…
View article: Assessing the selective impact of histone modifying drugs on adenoid cystic carcinoma cells and their stem cell counterparts
Assessing the selective impact of histone modifying drugs on adenoid cystic carcinoma cells and their stem cell counterparts Open
View article: Facial nodular fasciitis in an adult patient: a case report of an uncommon manifestation
Facial nodular fasciitis in an adult patient: a case report of an uncommon manifestation Open
Nodular fasciitis is a pseudosarcomatous, self-limited lesion composed of fibroblasts and myofibroblasts. Craniofacial lesions are more common in pediatric patients. This report presents a rare case of nodular fasciitis involving the face …
View article: Development and validation of an artificial intelligence-based pipeline for predicting oral epithelial dysplasia malignant transformation
Development and validation of an artificial intelligence-based pipeline for predicting oral epithelial dysplasia malignant transformation Open
View article: The use of artificial intelligence in the diagnosis of odontogenic cysts and tumors
The use of artificial intelligence in the diagnosis of odontogenic cysts and tumors Open
The application of artificial intelligence (AI) in healthcare has garnered growing interest, particularly for its ability to improve diagnostic accuracy and streamline clinical workflows. This literature review examines the latest advancem…
View article: Advancing oral cancer diagnosis and risk assessment with artificial intelligence: a review
Advancing oral cancer diagnosis and risk assessment with artificial intelligence: a review Open
This narrative review aims to appraise the evidence on artificial intelligence models for early diagnosis and risk stratification of oral cancer, focusing on data modalities, methodology differences, applications in the diagnostic flow and…
View article: Wound healing and pain evaluation following diode laser surgery vs. conventional scalpel surgery in the surgical treatment of oral leukoplakia: a randomized controlled trial
Wound healing and pain evaluation following diode laser surgery vs. conventional scalpel surgery in the surgical treatment of oral leukoplakia: a randomized controlled trial Open
Objectives This study aimed to compare patient-reported pain scores and clinician-assessed healing outcomes following the treatment of oral leukoplakia (OL) with a diode laser vs. a conventional scalpel. Methods A randomized, double-blind …
View article: Tongue spindle cell rhabdomyosarcoma: case report in a pediatric patient
Tongue spindle cell rhabdomyosarcoma: case report in a pediatric patient Open
Rhabdomyosarcoma (RMS) is an uncommon soft tissue malignant tumor derived from striated muscle tissue. RMS is uncommon in the oral cavity. Herein, we reported the clinicopathological and immunohistochemical features of an RMS case in a 1-y…
View article: Cemento-ossifying fibroma in the anterior region of the mandible: a case report emphasizing a conservative surgical management
Cemento-ossifying fibroma in the anterior region of the mandible: a case report emphasizing a conservative surgical management Open
Cemento-ossifying fibroma (COF) is a slow-growing, well-defined unilocular benign mesenchymal odontogenic tumor, that can have sclerotic edges and mixed areas. This case report details a conservative surgical treatment approach for COF tha…
View article: Epithelial salivary gland neoplasms in pediatric patients: A comprehensive review
Epithelial salivary gland neoplasms in pediatric patients: A comprehensive review Open
This review highlights that SGTs in pediatric patients present distinct clinical features and prognostic outcomes compared to adults. Although they are rare in this age group, clinicians should remain vigilant to these neoplasms when asses…
View article: Comparative analysis of language models in addressing syphilis-related queries
Comparative analysis of language models in addressing syphilis-related queries Open
LLMs hold promise for disseminating syphilis information, but human oversight is crucial. AI models need refinement to improve their accuracy, especially in complex medical scenarios.
View article: An Exuberant Calcifying Epithelial Odontogenic Tumor in the Posterior Maxilla: A Case Report
An Exuberant Calcifying Epithelial Odontogenic Tumor in the Posterior Maxilla: A Case Report Open
This case report presents a rare instance of a Calcifying Epithelial Odontogenic Tumor (CEOT) in the maxilla of a 52-year-old male, characterized by a painless, growing mass and facial asymmetry. Imaging revealed extensive involvement of t…
View article: Tongue spindle cell rhabdomyosarcoma: case report in a pediatric patient
Tongue spindle cell rhabdomyosarcoma: case report in a pediatric patient Open
Rhabdomyosarcoma (RMS) is an uncommon soft tissue malignant tumor derived from striated muscle tissue. RMS is uncommon in the oral cavity. Herein, we reported the clinicopathological and immunohistochemical features of an RMS case in a 1-y…
View article: Grading systems and perineural invasion in oral squamous cell carcinoma - a disease-specific survival analysis
Grading systems and perineural invasion in oral squamous cell carcinoma - a disease-specific survival analysis Open
Besides clinical stage and histological grade, PNI also showed to be a crucial prognostic factor in OSCC, necessitating aggressive treatment strategies.
View article: Impact of CD68, CD4, TNF-α, and COX-2 expression on disease-specific survival in Brazilian patients with OSCC
Impact of CD68, CD4, TNF-α, and COX-2 expression on disease-specific survival in Brazilian patients with OSCC Open
Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck. Studies on the inflammatory pathways that have evolved during the development of the disease remain controversial. We assessed the expression of inflam…
View article: Development and internal validation of El-Shazly-Buchholz’s nomogram to predict postoperative complications after PCNL: A multicenter study
Development and internal validation of El-Shazly-Buchholz’s nomogram to predict postoperative complications after PCNL: A multicenter study Open
Introduction: A model to predict the risk of surgical complications following percutaneous nephrolithotomy (PCNL) could be a useful tool to guide clinical decision-making. The aim of this study was to develop a simple and widely applicable…
View article: Incipient ameloblastoma or odontogenic hamartomatous proliferation: is BRAFV600E mutation helpful to distinguish them?
Incipient ameloblastoma or odontogenic hamartomatous proliferation: is BRAFV600E mutation helpful to distinguish them? Open
The distinction between odontogenic hamartomatous proliferation and other odontogenic cysts and tumors poses a diagnostic challenge. This report presents a unique case of an 18-year-old male who complained of pain and pus discharge in the …
View article: Central odontogenic fibroma with giant cell granuloma-like features: a case report and comprehensive literature review
Central odontogenic fibroma with giant cell granuloma-like features: a case report and comprehensive literature review Open
Central odontogenic fibroma (COF) is a rare benign tumor from odontogenic mesenchyme, accounting for less than 5% of odontogenic tumors. Central giant cell granuloma (CGCG) is also benign but locally aggressive, featuring multinucleated gi…
View article: Oral squamous cell carcinoma adjacent to dental implant – a case report with a long-term follow-up
Oral squamous cell carcinoma adjacent to dental implant – a case report with a long-term follow-up Open
Head and neck cancers are a growing global health concern, with oral squamous cell carcinoma (OSCC) accounting for 90-95% of all cases within this region. OSCC near dental implants can resemble benign inflammatory lesions, posing diagnosis…
View article: Clinicopathological profile of non-hodgkin lymphomas affecting the parotid glands
Clinicopathological profile of non-hodgkin lymphomas affecting the parotid glands Open
Objetivo: The aim of this study is to investigate the clinicopathological and immunohistochemical features of a series of lymphomas involving the parotid glands. Methods: All cases diagnosed in one pathology service from January 2008 and D…
View article: Investigating the safety of photobiomodulation in oral carcinogenesis: insights into cell proliferation, invasion, and apoptosis via the 4NQO model
Investigating the safety of photobiomodulation in oral carcinogenesis: insights into cell proliferation, invasion, and apoptosis via the 4NQO model Open
View article: Development and Validation of an Artificial Intelligence-based Pipeline for Predicting Oral Epithelial Dysplasia Malignant Transformation
Development and Validation of an Artificial Intelligence-based Pipeline for Predicting Oral Epithelial Dysplasia Malignant Transformation Open
Oral epithelial dysplasia (OED) is a potentially malignant histopathological diagnosis given to lesions of the oral cavity that are at risk of progression to malignancy. Manual grading of OED is subject to substantial variability and does …
View article: Plasmablastic Lymphoma in the Submandibular Region Diagnosed by FNAC: A Case Report and Literature Review
Plasmablastic Lymphoma in the Submandibular Region Diagnosed by FNAC: A Case Report and Literature Review Open
Objective This study aims to provide a literature review of FNAC‐diagnosed plasmablastic lymphoma (PBL) cases and present a case of PBL in an HIV patient diagnosed by FNAC. Methods A literature review was conducted across eight databases t…
View article: Clinicopathological and immunohistochemical study of canalicular adenoma
Clinicopathological and immunohistochemical study of canalicular adenoma Open
Objective: To evaluate the clinicopathological and immunohistochemical features of an original series of canalicular adenoma. Methods: Cases diagnosed as canalicular adenoma from a single center were retrospectively retrieved and clinical …
View article: Diagnosis of HPV-associated oropharyngeal squamous cell carcinoma in a middle-income country: report of two new cases
Diagnosis of HPV-associated oropharyngeal squamous cell carcinoma in a middle-income country: report of two new cases Open
Human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is a distinct subset characterized by better treatment responses and higher survival rates. Clinical and morphological aspects are crucial for diagnosis. H…
View article: Deep Convolutional Neural Network for Accurate Classification of Myofibroblastic Lesions on Patch-Based Images
Deep Convolutional Neural Network for Accurate Classification of Myofibroblastic Lesions on Patch-Based Images Open
View article: Oral/Perioral Reactions to Injectable Soft Tissue Fillers: A Clinicopathological Multicentric Study
Oral/Perioral Reactions to Injectable Soft Tissue Fillers: A Clinicopathological Multicentric Study Open
Objective To analyze the characteristics of a series of oral reactions to injectable soft tissue fillers. Materials and Methods Cases diagnosed as oral reactions to injectable soft tissue fillers were selected from eight Pathology laborato…