Paavo Raittinen
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View article: Use of Antidepressants Decreased After Initiation of <scp>ADHD</scp> Treatment in Adults—A Finnish Nationwide Register Study Describing Use of <scp>ADHD</scp> and Non‐<scp>ADHD</scp> Medication in People With and Without <scp>ADHD</scp>
Use of Antidepressants Decreased After Initiation of <span>ADHD</span> Treatment in Adults—A Finnish Nationwide Register Study Describing Use of <span>ADHD</span> and Non‐<span>ADHD</span> Medication in People With and Without <span>ADHD</span> Open
Introduction ADHD is often associated with comorbid psychiatric conditions. Differential diagnosis between other conditions and ADHD is not always clear, and patients are sometimes initially treated for another disorder instead. ADHD diagn…
View article: Phenotypic and transcriptomic characterization of bicalutamide and enzalutamide resistance in castration-resistant prostate cancer cells
Phenotypic and transcriptomic characterization of bicalutamide and enzalutamide resistance in castration-resistant prostate cancer cells Open
The cornerstone treatment for aggressive prostate cancer (PCa) is androgen deprivation therapy (ADT). Eventually PCa cells develop castration resistance, i.e. resistance to ADT. Castration resistant PCa initially responds to androgen signa…
View article: Increase in Occurrence of Attention Deficit Hyperactivity Disorder Differs by Age Group and Gender—Finnish Nationwide Register Study
Increase in Occurrence of Attention Deficit Hyperactivity Disorder Differs by Age Group and Gender—Finnish Nationwide Register Study Open
Introduction This study describes epidemiology of attention deficit hyperactivity disorder (ADHD) and use of ADHD medication across all age groups in Finland. Methods This retrospective study is based on nationwide registers in Finland. Th…
View article: Elevated Levels of Serum Thymidine Kinase 1 Predict Poor Survival for Patients with Metastatic Prostate Cancer
Elevated Levels of Serum Thymidine Kinase 1 Predict Poor Survival for Patients with Metastatic Prostate Cancer Open
We found that for patients with metastatic prostate cancer, high levels of a protein called TK1 that is involved in cell division was linked to higher risk of death. Our findings need to be confirmed in other studies.
View article: Healthcare Resource Utilization and Associated Costs During the First 5 Years After Diagnosis and at the End of Life: A Nationwide Cohort Study of Patients with Multiple Myeloma in Finland
Healthcare Resource Utilization and Associated Costs During the First 5 Years After Diagnosis and at the End of Life: A Nationwide Cohort Study of Patients with Multiple Myeloma in Finland Open
During active treatment, MM is primarily treated in the specialized care setting, with outpatient medication and visits to specialized care being the main cost drivers. These results can be utilized to estimate the need for care and expect…
View article: Cystic fibrosis patient characteristics and healthcare resource utilization in Finland using linked registries
Cystic fibrosis patient characteristics and healthcare resource utilization in Finland using linked registries Open
The prevalence of CF in Finland is remarkably low, likely reflecting unique population characteristics and, in part, delayed diagnosis. Antibiotic use is frequent among Finnish people with CF. Inpatient hospital visits are >30 times higher…
View article: Recent trends in incidence, survival and treatment of multiple myeloma in Finland – a nationwide cohort study
Recent trends in incidence, survival and treatment of multiple myeloma in Finland – a nationwide cohort study Open
View article: Randomised double-blind phase 3 clinical study testing impact of atorvastatin on prostate cancer progression after initiation of androgen deprivation therapy: study protocol
Randomised double-blind phase 3 clinical study testing impact of atorvastatin on prostate cancer progression after initiation of androgen deprivation therapy: study protocol Open
Introduction Blood cholesterol is likely a risk factor for prostate cancer prognosis and use of statins is associated with lowered risk of prostate cancer recurrence and progression. Furthermore, use of statins has been associated with pro…
View article: Outcomes of Screening for Prostate Cancer Among Men Who Use Statins
Outcomes of Screening for Prostate Cancer Among Men Who Use Statins Open
In this post hoc subgroup analysis of a cohort from a population-based randomized clinical trial, PSA screening among statin users was associated with a decreased incidence of advanced prostate cancer that was similar among statin nonusers…
View article: Nationwide infection control strategy lowered seasonal respiratory infection rate: occupational health care perspective during the COVID-19 epidemic in Finland
Nationwide infection control strategy lowered seasonal respiratory infection rate: occupational health care perspective during the COVID-19 epidemic in Finland Open
Nationwide infection control strategies were effective to slow down the spread of common respiratory infectious diseases in the occupational population.
View article: Atorvastatin induces adrenal androgen downshift in men with prostate cancer: A post Hoc analysis of a pilot adaptive Randomised clinical trial
Atorvastatin induces adrenal androgen downshift in men with prostate cancer: A post Hoc analysis of a pilot adaptive Randomised clinical trial Open
View article: Prostate cancer prognosis after initiation of androgen deprivation therapy among statin users. A population-based cohort study
Prostate cancer prognosis after initiation of androgen deprivation therapy among statin users. A population-based cohort study Open
View article: Single Cell Trapping by Superhydrophobic/Superhydrophilic Microarrays
Single Cell Trapping by Superhydrophobic/Superhydrophilic Microarrays Open
Single cell trapping is demonstrated on superhydrophobic–superhydrophilic patterned microarrays. Superhydrophilic spots that are twice the size of the cells to be trapped are found to be optimal for obtaining single cell trapping. The sing…
View article: Antidiabetic Drugs and Prostate Cancer Prognosis in a Finnish Population-Based Cohort
Antidiabetic Drugs and Prostate Cancer Prognosis in a Finnish Population-Based Cohort Open
Background: Hyperinsulemia and glycemic control may play a role as prostate cancer prognostic factors, whereas use of certain antidiabetic drugs, that is metformin, could improve the prognosis. We examined the link between antidiabetic med…
View article: Circulatory and prostatic tissue lipidomic profiles shifts after high-dose atorvastatin use in men with prostate cancer
Circulatory and prostatic tissue lipidomic profiles shifts after high-dose atorvastatin use in men with prostate cancer Open
View article: Microfabricated single-cell capture technology
Microfabricated single-cell capture technology Open
Single cell ribonucleic acid (RNA) analysis is a next generation sequencing method where the genotype is defined in a single cell resolution. First criteria in single cell analysis is to capture precisely single cell for analysis. Two most…