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View article: Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m <sup>7</sup> G-cap-dependent translation at the 8- to 16-cell transition
Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m <sup>7</sup> G-cap-dependent translation at the 8- to 16-cell transition Open
Preimplantation mouse embryo development involves temporal–spatial specification and segregation of three blastocyst cell lineages: trophectoderm, primitive endoderm and epiblast. Spatial separation of the outer-trophectoderm lineage from …
View article: Spatial positioning of preimplantation mouse embryo blastomeres is regulated by mTORC1 and 7mG-cap dependent translation at the 8- to 16-cell transition
Spatial positioning of preimplantation mouse embryo blastomeres is regulated by mTORC1 and 7mG-cap dependent translation at the 8- to 16-cell transition Open
Preimplantation stages of mouse embryo development involve temporal and spatial specification and segregation of three late blastocyst cell lineages; trophectoderm (TE), primitive endoderm (PrE) and epiblast (EPI). Spatial separation of th…
View article: Table S5 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition
Table S5 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition Open
List of significantly differently changing proteins between control and mTORi embryos at E2.5+8h and E2.5+9h. Microsoft Excel worksheet
View article: Table S4 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition
Table S4 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition Open
Numbers of inner, outer and SAD blastomeres for embryos analysed in figure 4. Microsoft Excel worksheet
View article: Table S1 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition
Table S1 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition Open
umbers of inner, outer and SAD blastomeres for embryos analysed in figure 2a. Microsoft Excel worksheet
View article: Table S3 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition
Table S3 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition Open
Numbers of inner, outer and SAD blastomeres for embryos analysed in figure 2c. Microsoft Excel worksheet
View article: Table S2 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition
Table S2 from Spatial positioning of preimplantation mouse embryo cells is regulated by mTORC1 and m<sup>7</sup>G-cap-dependent translation at the 8- to 16-cell transition Open
Numbers of inner, outer and SAD blastomeres for embryos analysed in figure 2b. Microsoft Excel worksheet
View article: DDX21 is a p38-MAPK-sensitive nucleolar protein necessary for mouse preimplantation embryo development and cell-fate specification
DDX21 is a p38-MAPK-sensitive nucleolar protein necessary for mouse preimplantation embryo development and cell-fate specification Open
Successful navigation of the mouse preimplantation stages of development, during which three distinct blastocyst lineages are derived, represents a prerequisite for continued development. We previously identified a role for p38-mitogen-act…
View article: DDX21 is a p38-MAPK sensitive nucleolar protein necessary for mouse preimplantation embryo development and cell-fate specification
DDX21 is a p38-MAPK sensitive nucleolar protein necessary for mouse preimplantation embryo development and cell-fate specification Open
Successful navigation of the mouse preimplantation stages of development, during which three distinct blastocyst lineages are derived, represents a prerequisite for continued development. We previously identified a role for p38-mitogen-act…
View article: Supplementary Data Tables.xlsx from DDX21 is a p38-MAPK sensitive nucleolar protein necessary for mouse preimplantation embryo development and cell-fate specification
Supplementary Data Tables.xlsx from DDX21 is a p38-MAPK sensitive nucleolar protein necessary for mouse preimplantation embryo development and cell-fate specification Open
Successful navigation of the mouse preimplantation stages of development, during which three distinct blastocyst lineages are derived, represents a prerequisite for continued development. We previously identified a role for p38-mitogen-act…
View article: p38-MAPK mediated rRNA processing and translation regulation enables PrE differentiation during mouse blastocyst maturation
p38-MAPK mediated rRNA processing and translation regulation enables PrE differentiation during mouse blastocyst maturation Open
Background p38-MAPKs are stress-activated kinases necessary for placental development and nutrient and oxygen transfer during murine post-implantation development. In preimplantation development, p38-MAPK activity is required for blastocys…
View article: Wwc2 Is a Novel Cell Division Regulator During Preimplantation Mouse Embryo Lineage Formation and Oogenesis
Wwc2 Is a Novel Cell Division Regulator During Preimplantation Mouse Embryo Lineage Formation and Oogenesis Open
Formation of the hatching mouse blastocyst marks the end of preimplantation development, whereby previous cell cleavages culminate in the formation of three distinct cell lineages (trophectoderm, primitive endoderm and epiblast). We report…
View article: <i>Wwc2</i>is a novel cell division regulator during preimplantation mouse embryo lineage formation and oogenesis
<i>Wwc2</i>is a novel cell division regulator during preimplantation mouse embryo lineage formation and oogenesis Open
Formation of a mature and hatching mouse blastocyst marks the end of the preimplantation development, whereby regulated cell cleavages culminate in the formation of three distinct lineages. We report dysregulated expression of Wwc2 , an il…
View article: p38-Mitogen Activated Kinases Mediate a Developmental Regulatory Response to Amino Acid Depletion and Associated Oxidative Stress in Mouse Blastocyst Embryos
p38-Mitogen Activated Kinases Mediate a Developmental Regulatory Response to Amino Acid Depletion and Associated Oxidative Stress in Mouse Blastocyst Embryos Open
Maternal starvation coincident with preimplantation development has profound consequences for placental-fetal development, with various identified pathologies persisting/manifest in adulthood; the 'Developmental Origin of Health and Diseas…
View article: p38-mitogen activated kinases mediate a developmental regulatory response to amino acid depletion and associated oxidative stress in mouse blastocyst embryos
p38-mitogen activated kinases mediate a developmental regulatory response to amino acid depletion and associated oxidative stress in mouse blastocyst embryos Open
Maternal starvation coincident with preimplantation development has profound consequences for placental-foetal development, with various identified pathologies persisting/manifest in adulthood; the ‘Developmental Origin of Health and Disea…