Juan Pablo Martínez
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View article: Long-term prediction of heart failure using an ECG-based fine-tuned self-supervised neural network model identifies 23 genetic loci implicating electrophysiological mechanisms
Long-term prediction of heart failure using an ECG-based fine-tuned self-supervised neural network model identifies 23 genetic loci implicating electrophysiological mechanisms Open
Background Risk stratification of heart failure (HF) in individuals without prevalent heart disease is crucial for early intervention and prevention. Electrocardiogram (ECG)-based artificial intelligence models have shown promise when pred…
View article: First Row Transition Metals in Olefin Metathesis: The Role of Iron and Manganese
First Row Transition Metals in Olefin Metathesis: The Role of Iron and Manganese Open
Olefin metathesis has traditionally been dominated by molybdenum and ruthenium‐based catalysts, but the pursuit of sustainable and earth‐abundant alternatives has driven interest in first‐row transition metals particularly iron. While iron…
View article: Digital monitoring and electronic patient-reported outcomes collection following atrial fibrillation ablation
Digital monitoring and electronic patient-reported outcomes collection following atrial fibrillation ablation Open
Systematic electronic PROM collection after AF ablation is feasible in clinical practice. Structured digital-blended integrated care guarantees continuity of AF management and supports earlier detection and treatment of recurrences.
View article: Predicting diabetes mellitus metabolic goals and chronic complications transitions—analysis based on natural language processing and machine learning models
Predicting diabetes mellitus metabolic goals and chronic complications transitions—analysis based on natural language processing and machine learning models Open
Objective To estimate Diabetes mellitus (DM) progression at one and two years in terms of glycemic targets and development of complications. Research design and methods We analyzed a retrospective cohort of adult DM patients treated in a H…
View article: Sudden Cardiac Death Risk Prediction from QT–RR Adaptation Time Lag Computed from Exercise Stress Test ECG
Sudden Cardiac Death Risk Prediction from QT–RR Adaptation Time Lag Computed from Exercise Stress Test ECG Open
A prolonged QT-RR adaptation time during the recovery phase of the EST ECG, calculated with the RR-based strategy, can predict SCD and CVD, providing complementary information to other clinical markers.
View article: Evaluación de la dinámica de la onda T en pacientes con síndrome de QT largo
Evaluación de la dinámica de la onda T en pacientes con síndrome de QT largo Open
En este trabajo evaluamos la habilidad del índice de variación morfológica basado en la deformación temporal, dw, en la clasificación de pacientes con síndrome de QT largo (SQTL) e individuos de control sanos (GC), así como pacientes con S…
View article: Performance Evaluation of QT-RR Adaptation Time Lag Estimation in Exercise Stress Testing
Performance Evaluation of QT-RR Adaptation Time Lag Estimation in Exercise Stress Testing Open
Using simulated ECGs, the performance evaluation of the proposed method shows that the estimated time lag agrees well with the true time lag.
View article: T-Wave Peak-to-End Changes Quantified by Time-Warping Predicts Ventricular Fibrillation in a Porcine Myocardial Infarction Model
T-Wave Peak-to-End Changes Quantified by Time-Warping Predicts Ventricular Fibrillation in a Porcine Myocardial Infarction Model Open
The time-warping-based index, [Formula: see text], is a stronger VF predictor than [Formula: see text] during ischemia in a porcine model, advising for further clinical exploration studies in humans.
View article: Argentophilic Interactions, Flexibility, and Dynamics of Pyrrole Cages Encapsulating Silver(I) Clusters
Argentophilic Interactions, Flexibility, and Dynamics of Pyrrole Cages Encapsulating Silver(I) Clusters Open
Recently, pyrrole cages have been synthesized that encapsulate ion pairs and silver(I) clusters to form intricate supramolecular capsules. We report here a computational analysis of these structures using density functional theory combined…
View article: Spatial Dispersion of Activation and Repolarization Times Associated with Different Cardiac Pacing Modes
Spatial Dispersion of Activation and Repolarization Times Associated with Different Cardiac Pacing Modes Open
Various modes of ventricular pacing are currently applied to patients with an indication for permanent pacemaker implantation. The so-called physiological pacing modes, like His bundle pacing (HBP) and left bundle branch pacing (LBBP), sti…
View article: A Multi-layer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population
A Multi-layer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population Open
Life-threatening ventricular arrhythmias (LTVA) prediction in individuals without cardiovascular disease remains a major challenge. We tested the performance of a multilayer convolutional neural network (CNN) using ECG signals, age and sex…
View article: Changes in T-peak-to-T-end Morphology Measured by Time-Warping Are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model
Changes in T-peak-to-T-end Morphology Measured by Time-Warping Are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model Open
In this work, we use a time-warping-based morphology variation index, d_{w}, computed between the peak and the end of the T-wave, and assess its association with the occurrence of ventricular fibrillation (VF) episodes in ischemic conditio…
View article: Combining hypothesis-driven ECG indices with machine learning improves ventricular arrhythmic risk prediction in a low-risk population
Combining hypothesis-driven ECG indices with machine learning improves ventricular arrhythmic risk prediction in a low-risk population Open
Background Life-threatening ventricular arrhythmias (LTVA) are a leading cause of mortality, but early identification of high-risk individuals remains a major challenge. An ECG index, TMV (T-wave morphology variations), predicts LTVA in 51…
View article: Time-Warping Analysis of the T-Wave Peak-to-End Interval to Quantify Ventricular Repolarization Dispersion During Ischemia
Time-Warping Analysis of the T-Wave Peak-to-End Interval to Quantify Ventricular Repolarization Dispersion During Ischemia Open
Variations in the dispersion of ventricular repolarization can be quantified by T-wave time-warping based index, dw. However, the early phase of the T-wave can be affected by ST-segment changes during ischemia. We hypothesized t…
View article: Los cambios en la morfología del intervalo Tpico-Tfin medidos mediante time-warping se asocian con la fibrilación ventricular inducida por la isquemia en un modelo porcino
Los cambios en la morfología del intervalo Tpico-Tfin medidos mediante time-warping se asocian con la fibrilación ventricular inducida por la isquemia en un modelo porcino Open
La dispersión de la repolarización ventricular reflejada en el intervalo Tpe ha mostrado potencial en la predicción del riesgo arrítmico, y no está expuesta a errores de anotación en la determinación del inicio de la onda T como consecuenc…
View article: ECG Modeling for Simulation of Arrhythmias in Time-Varying Conditions
ECG Modeling for Simulation of Arrhythmias in Time-Varying Conditions Open
The present article proposes an ECG simulator that advances modeling of arrhythmias and noise by introducing time-varying signal characteristics. The simulator is built around a discrete-time Markov chain model for simulating atrial and ve…
View article: QT interval time lag in response to heart rate changes during stress test for Coronary Artery Disease diagnosis
QT interval time lag in response to heart rate changes during stress test for Coronary Artery Disease diagnosis Open
Background: Slow adaptation of the QT interval to abrupt changes in heart rate (HR) can enhance ventricular heterogeneity and has been suggested as a marker of arrhythmic risk. Most investigations on QT rate adaptation lag have been perfor…
View article: Editorial: Atrial Fibrillation: Technologies for Investigation, Monitoring and Treatment, Volume II
Editorial: Atrial Fibrillation: Technologies for Investigation, Monitoring and Treatment, Volume II Open
[No abstract]
View article: The role of β-adrenergic stimulation in QT interval adaptation to heart rate during stress test
The role of β-adrenergic stimulation in QT interval adaptation to heart rate during stress test Open
The adaptation lag of the QT interval after heart rate (HR) has been proposed as an arrhythmic risk marker. Most studies have quantified the QT adaptation lag in response to abrupt, step-like changes in HR induced by atrial pacing, in resp…
View article: Harnessing Machine Learning for Smart Agriculture: Integrating Data-Driven Approaches for Crop Improvement
Harnessing Machine Learning for Smart Agriculture: Integrating Data-Driven Approaches for Crop Improvement Open
View article: Spanish-Aragonese LMF Apertium Bilingual dictionary
Spanish-Aragonese LMF Apertium Bilingual dictionary Open
This is the LMF version of the Apertium bilingual dictionary for Spanish and Aragonese languages. Bilingual LMF dictionaries were generated from Apertium bilingual dix files. For each Apertium bilingual correspondence, the corresponding so…
View article: Right Ventricular vs Left Bundle Branch Pacing-Induced Changes in ECG Depolarization and Repolarization
Right Ventricular vs Left Bundle Branch Pacing-Induced Changes in ECG Depolarization and Repolarization Open
Patients suffering from bradycardia are indicated for pacemaker implantation. Right ventricular pacing (RVP)has been conventionally used for this purpose, but it can increase the risk of atrial fibrillation and heart failure. Left\nbundle …
View article: Cosinor-Based Circadianity of T-Wave Alternans Activity as a Predictor of Sudden Cardiac Death in Heart Failure: a Post-Hoc Analysis of the GISSI-HF Holter Substudy
Cosinor-Based Circadianity of T-Wave Alternans Activity as a Predictor of Sudden Cardiac Death in Heart Failure: a Post-Hoc Analysis of the GISSI-HF Holter Substudy Open
Many studies in the last decades associate the existence of T-wave alternans (TWA) in the ECG to the risk of suffering malignant ventricular arrhythmias and sudden cardiac death (SCD).In this work, 24-hour Holter ECG recordings from 388 pa…
View article: Atrial fibrosis identification with unipolar electrogram eigenvalue distribution analysis in multi-electrode arrays
Atrial fibrosis identification with unipolar electrogram eigenvalue distribution analysis in multi-electrode arrays Open
View article: Spatial Correlation Between Myocyte's Repolarization Times and Their Alternans Drives T-Wave Alternans on the ECG
Spatial Correlation Between Myocyte's Repolarization Times and Their Alternans Drives T-Wave Alternans on the ECG Open
The metrics may reveal new complementary insights into the mechanisms underlying TWA.
View article: Analysis of P-wave Changes for Prediction of Atrial Fibrillation Episodes
Analysis of P-wave Changes for Prediction of Atrial Fibrillation Episodes Open
Atrial fibrillation (AF) is the most frequent arrhythmia in clinical practice. It usually initiates as a paroxysmal activity (PxAF), with the subject having sinus rhythm, with interleaved AF episodes.
The objective of the study is to eval…
View article: Desensibilización y reprocesamiento por movimientos oculares (EMDR) para trastornos ansiosos y depresivos en niños y adolescentes: revisión de la evidencia disponible.
Desensibilización y reprocesamiento por movimientos oculares (EMDR) para trastornos ansiosos y depresivos en niños y adolescentes: revisión de la evidencia disponible. Open
Introducción: la desensibilización y reprocesamiento por movimientos oculares (EMDR) tiene abundante evidencia de eficacia en desórdenes del espectro traumático. Su eficacia en trastornos ansiosos (TA) y depresivos (TD) en niños, niñ…
View article: Editorial: Atrial Fibrillation: Technology for Diagnosis, Monitoring, and Treatment
Editorial: Atrial Fibrillation: Technology for Diagnosis, Monitoring, and Treatment Open
EDITORIAL article Front. Physiol., 23 February 2022Sec. Cardiac Electrophysiology https://doi.org/10.3389/fphys.2022.848096
View article: Weighted Time Warping Improves T-Wave Morphology Markers Clinical Significance
Weighted Time Warping Improves T-Wave Morphology Markers Clinical Significance Open
The proposed WFs, with T showing the best performance, increased the robustness of time-warping based markers against TW location errors preserving their physiological information content and boosting their SCD risk stratification value. R…
View article: Análisis de dispersión de autovalores de electrogramas unipolares para la detección de fibrosis auricular
Análisis de dispersión de autovalores de electrogramas unipolares para la detección de fibrosis auricular Open
La fibrosis auricular representa un papel clave en la patogenia de la fibrilación auricular, y es un factor importante para el guiado de procedimientos de ablación con catéter. Se consideran fibróticas las áreas cuyos electrogramas bipolar…