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View article: Role of Coronary Artery Calcium Score CT in Risk Stratification of Asymptomatic Individuals
Role of Coronary Artery Calcium Score CT in Risk Stratification of Asymptomatic Individuals Open
Background: The evaluation of coronary artery disease has undergone significant transformation in recent years, with increasing emphasis on the detection and characterization of subclinical atherosclerotic plaques in order to improve cardi…
View article: Usefulness of cardiac rehabilitation programs among older patients undergoing transcatheter aortic valve replacement: how should we do it?
Usefulness of cardiac rehabilitation programs among older patients undergoing transcatheter aortic valve replacement: how should we do it? Open
Severe aortic stenosis has increased exponentially as a result of the aging of the population. Transcatheter aortic valve replacement (TAVR) procedures increase by 20%-30% per year in Spain. Referred patients are increasingly older, have c…
View article: Telematic intervention on frailty in patients undergoing TAVI. Design of the TELE-FRAIL TAVI clinical trial
Telematic intervention on frailty in patients undergoing TAVI. Design of the TELE-FRAIL TAVI clinical trial Open
Introduction and objectives: Although transcatheter aortic valve implantation (TAVI) is the first-line therapy for aortic stenosis (AS), its benefit could be lower (or even disappear) in frail patients. Physical exercise and nutritional su…
View article: Early diuretic response and outcome prediction in ambulatory worsening heart failure: Natriuresis versus diuresis
Early diuretic response and outcome prediction in ambulatory worsening heart failure: Natriuresis versus diuresis Open
Aims Early diuresis and natriuresis are commonly used to assess the efficacy of decongestive therapy following an acute heart failure episode. There is limited knowledge regarding which parameter better predicts adverse clinical outcomes, …
View article: Women's health: an imAging-based cardiovascular risK-rEdUction Program (WAKE UP) study. Rationale and design
Women's health: an imAging-based cardiovascular risK-rEdUction Program (WAKE UP) study. Rationale and design Open
Background Cardiovascular (CV) disease is the leading cause of death in women. Although 80% of CV disease events can be prevented, mortality is projected to increase, particularly in young women. Objectives To promote CV health in women an…
View article: Clinical utility and safety of finerenone in patients with heart failure: Rationale and design of FINE registry
Clinical utility and safety of finerenone in patients with heart failure: Rationale and design of FINE registry Open
Aims Information about current use of finerenone in patients with heart failure (HF) finerenone in clinical practice is scarce, and its effectiveness in clinical practice in patients is scarce. We aim to assess both the baseline clinical p…
View article: Ultrasound imaging of congestion in heart failure: a narrative review
Ultrasound imaging of congestion in heart failure: a narrative review Open
Despite exponential growing evidence supporting the use of ultrasound imaging in HF, LUS and venous Doppler analysis are not yet routine. Forthcoming evidence may help to consolidate these techniques in the management of HF patients.
View article: ST-Segment Elevation Myocardial Infarction Presentation in Apical Hypertrophic Cardiomyopathy
ST-Segment Elevation Myocardial Infarction Presentation in Apical Hypertrophic Cardiomyopathy Open
Recent studies demonstrate the relevance of apical ischemia in the pathophysiology of apical hypertrophic cardiomyopathy. This finding could explain why some patients may exhibit chest pain and dynamic ST-segment changes simulating an acut…
View article: Clinical profile of an unselected population with heart failure treated with vericiguat in real life: differences with the VICTORIA trial
Clinical profile of an unselected population with heart failure treated with vericiguat in real life: differences with the VICTORIA trial Open
Introduction Vericiguat, an oral stimulator of soluble guanylate cyclase, reduces cardiovascular mortality and hospitalisations in patients with heart failure (HF) and reduced ejection fraction, as demonstrated in the VICTORIA trial. This …
View article: One-year clinical events according to frailty in older patients with non-ST elevation acute coronary syndrome undergoing coronary angiography: an analysis of the IMPACT-TIMING-GO study
One-year clinical events according to frailty in older patients with non-ST elevation acute coronary syndrome undergoing coronary angiography: an analysis of the IMPACT-TIMING-GO study Open
In older patients with NSTEACS, frailty independently associates higher all-cause mortality or all-cause hospital admissions at one-year follow-up.
View article: Patient and Physician Perspectives on Cardiovascular Risk: A Multicenter Study of Communication Gaps
Patient and Physician Perspectives on Cardiovascular Risk: A Multicenter Study of Communication Gaps Open
Background Effective risk communication is crucial for managing cardiovascular disease, the leading cause of global mortality. Clear communication between patients and physicians is essential for informed decision-making, yet gaps in under…
View article: Routine invasive strategy and frailty burden in non-ST-segment elevation acute myocardial infarction
Routine invasive strategy and frailty burden in non-ST-segment elevation acute myocardial infarction Open
Adult patients with frailty and NSTEMI showed different prognosis according to the degree of frailty. A routine invasive strategy does not improve outcomes and might be harmful to the frailest patients.
View article: Heart Failure Knowledge Assessment and Perceived Patient Satisfaction in Heart Failure Units: A Multicenter Observational Survey
Heart Failure Knowledge Assessment and Perceived Patient Satisfaction in Heart Failure Units: A Multicenter Observational Survey Open
Background: Self-care and empowerment promotion in patients with heart failure (HF) is essential for improving their prognosis, but there is limited information concerning the patients' depth of knowledge about this pathology as well as pa…
View article: Current Management of Non-ST-Segment Elevation Acute Coronary Syndrome
Current Management of Non-ST-Segment Elevation Acute Coronary Syndrome Open
Cardiovascular disease constitutes the leading cause of morbimortality worldwide. Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is a common cardiovascular condition, closely related to the ageing population and significantly …
View article: Efficacy and safety of hypertonic saline therapy in ambulatory patients with heart failure: The <scp>SALT</scp> ‐ <scp>HF</scp> trial
Efficacy and safety of hypertonic saline therapy in ambulatory patients with heart failure: The <span>SALT</span> ‐ <span>HF</span> trial Open
Aims Combination of hypertonic saline solution (HSS) with intravenous loop diuretics has been suggested to improve diuretic response in patients hospitalized for heart failure (HF). The efficacy and safety of this approach in the ambulator…
View article: Development and Clinical Application of Left Ventricular–Arterial Coupling Non-Invasive Assessment Methods
Development and Clinical Application of Left Ventricular–Arterial Coupling Non-Invasive Assessment Methods Open
The constant and dynamic interaction between ventricular function and arterial afterload, known as ventricular-arterial coupling, is key to understanding cardiovascular pathophysiology. Ventricular–arterial coupling has traditionally been …
View article: The Impact of Geriatric Conditions in Elderly Patients with Coronary Heart Disease: A State-of-the-Art Review
The Impact of Geriatric Conditions in Elderly Patients with Coronary Heart Disease: A State-of-the-Art Review Open
The growing geriatric population presenting with coronary artery disease poses a primary challenge for healthcare services. This is a highly heterogeneous population, often underrepresented in studies and clinical trials, with distinctive …
View article: Invasive Treatment Strategy in Adults With Frailty and Non–ST-Segment Elevation Myocardial Infarction
Invasive Treatment Strategy in Adults With Frailty and Non–ST-Segment Elevation Myocardial Infarction Open
Importance The MOSCA-FRAIL randomized clinical trial compared invasive and conservative treatment strategies in patients with frailty with non–ST-segment elevation myocardial infarction (NSTEMI). It showed no differences in the number of d…
View article: Design and baseline characteristics of SALT‐HF trial: hypertonic saline therapy in ambulatory heart failure
Design and baseline characteristics of SALT‐HF trial: hypertonic saline therapy in ambulatory heart failure Open
Aims Hypertonic saline solution (HSS) plus intravenous (IV) loop diuretic appears to enhance the diuretic response in patients hospitalized for heart failure (HF). The efficacy and safety of this therapy in the ambulatory setting have not …
View article: Non-ST Elevation Myocardial Infarction in the Elderly. Antithrombotic Therapy and Beyond
Non-ST Elevation Myocardial Infarction in the Elderly. Antithrombotic Therapy and Beyond Open
Non-ST segment elevation myocardial infarction (NSTEMI) is the most frequent type of acute coronary syndrome in the elderly. Antithrombotic therapy is the cornerstone of pharmacological therapy in the setting of an acute ischemic event, a …
View article: Outcome and Morphofunctional Changes on Cardiac Magnetic Resonance in Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination
Outcome and Morphofunctional Changes on Cardiac Magnetic Resonance in Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination Open
Outcome and Morphofunctional Changes on Cardiac Magnetic Resonance in Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination
View article: Do Women Physicians Accept and Follow Heart Failure Guidelines More Than Men?
Do Women Physicians Accept and Follow Heart Failure Guidelines More Than Men? Open
A total of 387 physicians-173 women (44.7%)-from 128 different centers completed the survey. Compared to men, women were significantly younger (38.2 ± 9.1 years vs. 40.6 ± 11.2 years; p = 0.024) and had fewer years of clinical practice (12…
View article: Extended use of dual antiplatelet therapy among older adults with acute coronary syndromes and associated variables: a cohort study
Extended use of dual antiplatelet therapy among older adults with acute coronary syndromes and associated variables: a cohort study Open
Background Current guidelines recommend extending the use of dual antiplatelet therapy (DAPT) beyond 1 year in patients with an acute coronary syndrome (ACS) and a high risk of ischaemia and low risk of bleeding. No data exist about the im…
View article: Effect of Routine Invasive vs Conservative Strategy in Older Adults With Frailty and Non–ST-Segment Elevation Acute Myocardial Infarction
Effect of Routine Invasive vs Conservative Strategy in Older Adults With Frailty and Non–ST-Segment Elevation Acute Myocardial Infarction Open
Importance To our knowledge, no randomized clinical trial has compared the invasive and conservative strategies in frail, older patients with non–ST-segment elevation acute myocardial infarction (NSTEMI). Objective To compare outcomes of i…
View article: Use of Direct Acting Oral Anticoagulants in Elderly Patients with Atrial Fibrillation: A Multicenter, Cross-Sectional Study in Spain
Use of Direct Acting Oral Anticoagulants in Elderly Patients with Atrial Fibrillation: A Multicenter, Cross-Sectional Study in Spain Open
Non-vitamin K antagonist oral anticoagulants (NOACs) have substantially improved anticoagulation. However, data on NOAC use among elderly patients are scarce. We sought to describe NOAC use among elderly AF patients in Spain. We performed …
View article: Do Elderly Patients with Heart Failure and Reduced Ejection Fraction Benefit from Pharmacological Strategies for Prevention of Arrhythmic Events?
Do Elderly Patients with Heart Failure and Reduced Ejection Fraction Benefit from Pharmacological Strategies for Prevention of Arrhythmic Events? Open
Background: Heart failure is associated with aging. It is one of the leading causes of morbidity and mortality in Western countries and constitutes the main cause of hospitalization among elderly patients. The pharmacological therapy of pa…
View article: Review on the management of cardiovascular risk factors in the elderly.
Review on the management of cardiovascular risk factors in the elderly. Open
Cardiovascular risk factors (CVRF) are very prevalent in the elderly population and in addition to predisposing to cardiovascular disease they are related to functional decline, which limits the quality of life in this population. The obje…
View article: Multivessel spontaneous coronary artery dissection: clinical features, angiographic findings, management, and outcomes
Multivessel spontaneous coronary artery dissection: clinical features, angiographic findings, management, and outcomes Open
Background Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome. The rate of SCAD patients with multivessel (MV) involvement varies between series (6–13%)1,2. MV SCAD might be potentially associated to a…
View article: Sex differences in the impact of frailty in elderly outpatients with heart failure
Sex differences in the impact of frailty in elderly outpatients with heart failure Open
Introduction Frailty is common among patients with heart failure (HF). Our aim was to address the role of frailty in the management and prognosis of elderly men and women with HF. Methods and results Prospective multicenter registry that i…
View article: Infective Endocarditis in the Elderly: Challenges and Strategies
Infective Endocarditis in the Elderly: Challenges and Strategies Open
The specific management of infective endocarditis (IE) in elderly patients is not specifically addressed in recent guidelines despite its increasing incidence and high mortality in this population. The term “elderly” corresponds to differe…