Paige Helmer
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View article: The nucleoporin Nup153 is the anchor for Kif1a during basal nuclear migration in brain progenitor cells
The nucleoporin Nup153 is the anchor for Kif1a during basal nuclear migration in brain progenitor cells Open
View article: The Role of Nde1 phosphorylation in interkinetic nuclear migration and neural migration during cortical development
The Role of Nde1 phosphorylation in interkinetic nuclear migration and neural migration during cortical development Open
Nde1 is a cytoplasmic dynein regulatory protein with important roles in vertebrate brain development. One noteworthy function is in the nuclear oscillatory behavior in neural progenitor cells, the control and mechanism of which remain poor…
View article: The Role of Nde1 Phosphorylation in Interkinetic Nuclear Migration and Schizophrenia
The Role of Nde1 Phosphorylation in Interkinetic Nuclear Migration and Schizophrenia Open
Nde1 is a cytoplasmic dynein regulatory protein with important roles in vertebrate brain development. One noteworthy function is in the nuclear oscillatory behavior in neural progenitor cells, the control and mechanism of which remain poor…
View article: A two-kinesin mechanism controls neurogenesis in the developing brain
A two-kinesin mechanism controls neurogenesis in the developing brain Open
View article: The Nucleoporin Nup153 Is the Anchor for Kif1a during Basal Nuclear migration in Brain Progenitor Cells
The Nucleoporin Nup153 Is the Anchor for Kif1a during Basal Nuclear migration in Brain Progenitor Cells Open
Radial glial progenitors (RGPs) are highly elongated epithelial cells that give rise to most stem cells, neurons, and glia, in the vertebrate cerebral cortex. During development the RGP nuclei exhibit a striking pattern of cell cycle-depen…
View article: Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders
Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders Open
Bicaudal D2 (BICD2) is responsible for recruiting cytoplasmic dynein to diverse forms of subcellular cargo for their intracellular transport. Mutations in the human BICD2 gene have been found to cause an autosomal dominant form of spinal m…