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View article: Comparison of room times between pulsed-field ablation and very high-power short-duration ablation
Comparison of room times between pulsed-field ablation and very high-power short-duration ablation Open
Background Pulsed-field ablation (PFA) has shown promise in improving atrial fibrillation (AF) ablation efficiency by reducing skin-to-skin procedure times while maintaining safety compared to advanced radiofrequency (RF) methods such as v…
View article: Comparing cerebral microembolisation patterns between high power short duration and pulsed field ablation techniques using artificial intelligence based robotic transcranial doppler monitoring
Comparing cerebral microembolisation patterns between high power short duration and pulsed field ablation techniques using artificial intelligence based robotic transcranial doppler monitoring Open
Thromboembolism is a rare (<1%) complication of atrial fibrillation (AF) ablation , but the incidence of silent ischaemic lesions (SIL) is 5-15% (1). Artificial intelligence (AI)-based robotic transcranial Doppler (r-TCD) enables real-t…
View article: Unsupervised machine learning defines subgroups in ischemic heart disease patients presenting with ventricular tachycardia
Unsupervised machine learning defines subgroups in ischemic heart disease patients presenting with ventricular tachycardia Open
Background Ventricular tachycardia (VT) in ischemic heart disease (IHD) is the leading cause of sudden cardiac death (SCD). Despite the well-defined recommendations, tailoring therapies individually is often a challenge owing to the great …
View article: Left and right ventricular function measured by strain analysis predicts one-year mortality in ventricular tachycardia ablation patients with structural heart disease
Left and right ventricular function measured by strain analysis predicts one-year mortality in ventricular tachycardia ablation patients with structural heart disease Open
Introduction Radiofrequency catheter ablation has become increasingly important in the management of scar-related ventricular tachycardia (VT). Wide range of clinical and procedural predictors of VT recurrence and mortality are described b…
View article: Comparison of eplerenone and spironolactone treatment in patients with ischemic heart disease hospitalized due to ventricular tachycardia
Comparison of eplerenone and spironolactone treatment in patients with ischemic heart disease hospitalized due to ventricular tachycardia Open
Background The beneficial effects of mineralocorticoid receptor antagonists (MRAs) regarding sudden cardiac death (SCD) risk and cardiac remodeling are well known, moreover, they also reduce episodes of ventricular tachycardia (VT). Howeve…
View article: Early rapid local impedance drop is associated with acute lesion efficacy during pulmonary vein isolation using a novel contact force sensing catheter
Early rapid local impedance drop is associated with acute lesion efficacy during pulmonary vein isolation using a novel contact force sensing catheter Open
Introduction The predictive role of adequate local impedance drop in lesion formation using a novel contact force sensing ablation catheter for pulmonary vein isolation was recently described. The purpose of our study was to assess the tem…
View article: Machine learning based risk stratification of patients undergoing ventricular tachycardia ablation
Machine learning based risk stratification of patients undergoing ventricular tachycardia ablation Open
Background Monomorphic ventricular tachycardia (VT) is a potentially life-threatening condition. Although radiofrequency catheter ablation represents an effective treatment method for many of these patients, significant variability is obse…
View article: Early local impedance drop during pulmonary vein isolation using a novel contact force sensing catheter is associated with acute lesion efficacy
Early local impedance drop during pulmonary vein isolation using a novel contact force sensing catheter is associated with acute lesion efficacy Open
Funding Acknowledgements Type of funding sources: None. Introduction The predictive role of adequate local impedance drop in lesion formation using a novel contact force sensing ablation catheter for pulmonary vein isolation was recently d…
View article: The role of local impedance drop in the acute lesion efficacy during pulmonary vein isolation performed with a new contact force sensing catheter
The role of local impedance drop in the acute lesion efficacy during pulmonary vein isolation performed with a new contact force sensing catheter Open
Funding Acknowledgements Type of funding sources: None. Background Pulmonary vein isolation (PVI) is the cornerstone treatment for paroxysmal atrial fibrillation (AF). The effective lesion creation during the PVI is essential to reach opti…
View article: Novel Insights into the Molecular Regulation of Ribonucleotide Reductase in Adrenocortical Carcinoma Treatment
Novel Insights into the Molecular Regulation of Ribonucleotide Reductase in Adrenocortical Carcinoma Treatment Open
Current systemic treatment options for patients with adrenocortical carcinomas (ACCs) are far from being satisfactory. DNA damage/repair mechanisms, which involve, e.g., ataxia-telangiectasia-mutated (ATM) and ataxia-telangiectasia/Rad3-re…
View article: Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis
Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis Open
Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the path…
View article: MicroRNA Expression Profiling in Adrenal Myelolipoma
MicroRNA Expression Profiling in Adrenal Myelolipoma Open
We have found significantly differentially expressed miRNAs in AML and adrenocortical tumors. Circulating hsa-miR-451a might be a promising minimally invasive biomarker of AML. The lack of significantly different expression of hsa-miR-483-…
View article: A mikro-RNS-ek patogenetikai és diagnosztikai szerepe mellékvesekéreg-carcinomában
A mikro-RNS-ek patogenetikai és diagnosztikai szerepe mellékvesekéreg-carcinomában Open
Adrenocortical tumours are quite prevalent. Most of these tumours are benign, hormonally inactive adrenocortical adenomas. Rare hormone-secreting adrenocortical adenomas are associated with severe clinical consequences, whereas the prognos…
View article: Evaluation and diagnostic potential of circulating extracellular vesicle-associated microRNAs in adrenocortical tumors
Evaluation and diagnostic potential of circulating extracellular vesicle-associated microRNAs in adrenocortical tumors Open
There is no available blood marker for the preoperative diagnosis of adrenocortical malignancy. The objective of this study was to investigate the expression of extracellular vesicle-associated microRNAs and their diagnostic potential in p…
View article: Keringő mikroRNS-ek az endokrin daganatok diagnosztikájában
Keringő mikroRNS-ek az endokrin daganatok diagnosztikájában Open
MicroRNAs (miRNA, miR) are short – 19–25 nucleotide long – single stranded (in their mature form), non-coding RNA molecules that regulate gene expression mostly at the posttranscriptional level. microRNAs are involved in the regulation of …
View article: Potential relevance of microRNAs in inter-species epigenetic communication, and implications for disease pathogenesis
Potential relevance of microRNAs in inter-species epigenetic communication, and implications for disease pathogenesis Open
MicroRNAs are short non-protein coding RNA molecules involved in the epigenetic regulation of gene expression. Recently, extracellular microRNAs have been described in body fluids that might enable epigenetic communication between distant …