Introduction: Alzheimer’s disease (AD) has a heterogeneous course and there is a dearth of long-term follow-up data on treatment adherence and mortality in AD patients from India. Materials and Methods: A total of 99 AD patients consecutively evaluated in a geriatric clinic in a tertiary care hospital in South India were followed up either by direct evaluation in a geriatric clinic/home visit where feasible or by teleconsultation. This was a retrospective study with a cross-sectional assessment. All AD patients ha…

Primary progressive aphasia (PPA) is a heterogeneous neurodegenerative condition characterized by loss of language function. The present review discusses that Non-invasive brain stimulation (NIBS) holds the potential to benefit these patients by inducing neuroplasticity in language networks. Studies have also shown that neuroplasticity in the language networks is accompanied by behavioural gains irrespective of the degree of regional atrophy in PPA patients. However, the generalizability of NIBS in remediating spe…

Background: Transcranial electrical stimulation (tES) is a non-invasive neuromodulation technique increasingly recognized for its therapeutic potential in psychiatric disorders. Recent advances have enabled its administration in home settings, potentially increasing accessibility, reducing costs, and overcoming logistical barriers to in-clinic care. This scoping review systematically maps the preliminary evidence on home-based tES interventions for psychiatric disorders, while also assessing their feasibility, saf…

Importance Transcranial direct current stimulation (tDCS) is emerging as a home-based intervention for neuropsychiatric conditions and cognitive enhancement. However, its effectiveness is limited by interindividual variability, as fixed-dose protocols have failed to account for anatomic differences influencing current delivery to targeted regions and treatment outcome. While computational modeling supports individualized dosing to improve consistency, experimental validation remains limited. Objective To compare t…

The study identifies the frontal montage as the most suitable for nfvPPA and the ventral montage for svPPA. This study highlights the importance of pathology-specific tDCS montage selection, emphasizing the need for variant-based modulation of the language network in PPA.