Pallavi Kakade
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View article: An IL-17-DUOX2 axis controls gastrointestinal colonization by<i>Candida albicans</i>
An IL-17-DUOX2 axis controls gastrointestinal colonization by<i>Candida albicans</i> Open
Candida albicans is a ubiquitous fungus in the human gut microbiome as well as a prevalent cause of opportunistic mucosal and systemic disease. There is currently little understanding, however, as to how crosstalk between C. albicans and t…
View article: The hyphal-specific toxin candidalysin promotes fungal gut commensalism
The hyphal-specific toxin candidalysin promotes fungal gut commensalism Open
Data show competition data for Candida colonization of the murine host in the presence of different bacterial populations
View article: Aneuploidy and gene dosage regulate filamentation and host colonization by <i>Candida albicans</i>
Aneuploidy and gene dosage regulate filamentation and host colonization by <i>Candida albicans</i> Open
Aneuploidy is a frequent occurrence in fungal species where it can alter gene expression and promote adaptation to a variety of environmental cues. Multiple forms of aneuploidy have been observed in the opportunistic fungal pathogen Candid…
View article: Comparative Evaluation of Penetrative and Adaptive Properties of Unfilled and Filled Resin-Based Sealants When Placed using Conventional acid Etching, Lasing, and Fissurotomy Bur Technique of Enamel Preparation
Comparative Evaluation of Penetrative and Adaptive Properties of Unfilled and Filled Resin-Based Sealants When Placed using Conventional acid Etching, Lasing, and Fissurotomy Bur Technique of Enamel Preparation Open
Background: There is a confusion regarding selection of unfilled or filled sealant and method of enamel preparation before sealant application. This study was carried out to compare three techniques of enamel preparation using both unfille…
View article: Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity
Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity Open
Systemic immunity is stringently regulated by commensal intestinal microbes, including the pathobiont Candida albicans. This fungus utilizes various transcriptional and morphological programs for host adaptation, but how this heterogeneity…
View article: <i>Candida albicans</i> Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract
<i>Candida albicans</i> Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract Open
Candida albicans is a pathobiont that colonizes multiple niches in the body including the gastrointestinal (GI) tract, but is also responsible for both mucosal and systemic infections. Despite its prevalence as a human commensal, the murin…
View article: Adaptation to the dietary sugar D-tagatose via genome instability in polyploid <i>Candida albicans</i> cells
Adaptation to the dietary sugar D-tagatose via genome instability in polyploid <i>Candida albicans</i> cells Open
The opportunistic fungal pathogen Candida albicans undergoes an unusual parasexual cycle wherein diploid cells mate to form tetraploid cells that can generate genetically diverse progeny via a nonmeiotic program of chromosome loss. The gen…
View article: Two negative regulators of biofilm development exhibit functional divergence in conferring virulence potential to<i>Candida albicans</i>
Two negative regulators of biofilm development exhibit functional divergence in conferring virulence potential to<i>Candida albicans</i> Open
Candida albicans, a human pathogen, carries an expanded family of Zn(II)2Cys6 transcription factors. A CTG clade-specific protein Zcf32 and its closely related protein Upc2, a well-conserved transcription factor across the various fungal s…
View article: Assessment of Alteration in Capnometry Monitoring during Intravenous Sedation with Midazolam for Oral Surgical Procedures
Assessment of Alteration in Capnometry Monitoring during Intravenous Sedation with Midazolam for Oral Surgical Procedures Open
Introduction Capnography is routinely used for monitoring of patients subjected to sedation for different surgical procedures. There is still paucity of data highlighting the capnographic assessment of patients on midazolam sedation underg…
View article: ZCF32, a fungus specific Zn(II)2 Cys6 transcription factor, is a repressor of the biofilm development in the human pathogen Candida albicans
ZCF32, a fungus specific Zn(II)2 Cys6 transcription factor, is a repressor of the biofilm development in the human pathogen Candida albicans Open