Min‐Hui Pan
YOU?
Author Swipe
View article: Bombyx mori Jun gene is involved in endoreplication of silk gland cells by regulating S-phase cell cycle genes
Bombyx mori Jun gene is involved in endoreplication of silk gland cells by regulating S-phase cell cycle genes Open
Endoreplication as a variant of the cell cycle is an important avenue of development and reproduction for organisms. Endoreplication-induced polyploid cells are pivotal in ensuring the normal size and function of tissues and organs. Howeve…
View article: <i>Bombyx mori Cdc25</i> is involved in regulating the G2/M phase of the silkworm cell cycle
<i>Bombyx mori Cdc25</i> is involved in regulating the G2/M phase of the silkworm cell cycle Open
Endoreplication plays a crucial role in the morphogenesis of various organs. The silk gland of Bombyx mori , which produces silk after maturation, engages in a unique cell cycle transition, mitosis‐to‐endoreplication, in the early stages o…
View article: The Natural Antherea pernyi Sericin Protein Suppresses Gastric Cancer Formation by Inhibiting Cell Proliferation and Inducing Cell Apoptosis
The Natural Antherea pernyi Sericin Protein Suppresses Gastric Cancer Formation by Inhibiting Cell Proliferation and Inducing Cell Apoptosis Open
Sericin, a natural macromolecular protein and the main component of silkworm cocoons, exhibits biocompatibility, excellent mechanical properties, and biodegradability. Previous research has confirmed that the sericin protein possesses anti…
View article: BmATAD3A mediates mitochondrial ribosomal protein expression to maintain the mitochondrial energy metabolism of the silkworm, <i>Bombyx mori</i>
BmATAD3A mediates mitochondrial ribosomal protein expression to maintain the mitochondrial energy metabolism of the silkworm, <i>Bombyx mori</i> Open
ATAD3A is a mitochondrial membrane protein belonging to the ATPase family that contains the AAA+ domain. It is widely involved in mitochondrial metabolism, protein transport, cell growth, development and other important life processes. It …
View article: The Bombyx mori singed Gene Is Involved in the High-Temperature Resistance of Silkworms
The Bombyx mori singed Gene Is Involved in the High-Temperature Resistance of Silkworms Open
Temperature is an important factor in the growth, development, survival, and reproduction of organisms. The high-temperature resistance mechanism of insects may be significant for use in the prevention and control of insect pests. The silk…
View article: Common strategies in silkworm disease resistance breeding research
Common strategies in silkworm disease resistance breeding research Open
The silkworm, which is considered a model invertebrate organism, was the first insect used for silk production in human history and has been utilized extensively throughout its domestication. However, sericulture has been plagued by variou…
View article: Erratum for Dong et al., “Nosema bombycis microRNA-like RNA 8 (Nb-milR8) Increases Fungal Pathogenicity by Modulating <i>BmPEX16</i> Gene Expression in Its Host, Bombyx mori”
Erratum for Dong et al., “Nosema bombycis microRNA-like RNA 8 (Nb-milR8) Increases Fungal Pathogenicity by Modulating <i>BmPEX16</i> Gene Expression in Its Host, Bombyx mori” Open
Volume 9, no. 2, e01048-21, 2021, https://doi.org/10.1128/Spectrum.01048-21. Page 3, Fig. 1A: The wrong version of the control (0 h p.i.) image was uploaded during preparation of final files for publication. The correct 0-h p.i. panel is s…
View article: Identification of the Key Functional Domains of Bombyx mori Nucleopolyhedrovirus IE1 Protein
Identification of the Key Functional Domains of Bombyx mori Nucleopolyhedrovirus IE1 Protein Open
The immediate early protein 1 (IE1) acts as a transcriptional activator and is essential for viral gene transcription and viral DNA replication. However, the key regulatory domains of IE1 remain poorly understood. Here, we analyzed the seq…
View article: BmCDK5 Affects Cell Proliferation and Cytoskeleton Morphology by Interacting with BmCNN in Bombyx mori
BmCDK5 Affects Cell Proliferation and Cytoskeleton Morphology by Interacting with BmCNN in Bombyx mori Open
The ordered cell cycle is important to the proliferation and differentiation of living organisms. Cyclin-dependent kinases (CDKs) perform regulatory functions in different phases of the cell cycle process to ensure order. We identified a h…
View article: Bombyx mori Nucleopolyhedrovirus (BmNPV) Induces G2/M Arrest to Promote Viral Multiplication by Depleting BmCDK1
Bombyx mori Nucleopolyhedrovirus (BmNPV) Induces G2/M Arrest to Promote Viral Multiplication by Depleting BmCDK1 Open
Understanding virus–host interaction is very important for delineating the mechanism involved in viral replication and host resistance. Baculovirus, an insect virus, can cause S or G2/M phase arrest in insect cells. However, the roles and …
View article: MicroRNA-6498-5p Inhibits Nosema bombycis Proliferation by Downregulating BmPLPP2 in Bombyx mori
MicroRNA-6498-5p Inhibits Nosema bombycis Proliferation by Downregulating BmPLPP2 in Bombyx mori Open
As microRNAs (miRNAs) are important expression regulators of coding RNA, it is important to characterize their role in the interaction between hosts and pathogens. To obtain a comprehensive understanding of the miRNA alternation in Bombyx …
View article: Nosema bombycis microRNA-like RNA 8 (Nb-milR8) Increases Fungal Pathogenicity by Modulating <i>BmPEX16</i> Gene Expression in Its Host, Bombyx mori
Nosema bombycis microRNA-like RNA 8 (Nb-milR8) Increases Fungal Pathogenicity by Modulating <i>BmPEX16</i> Gene Expression in Its Host, Bombyx mori Open
A thorough understanding of fungal pathogen adaptations is essential for treating fungal infections. Recent studies have suggested that the role of small RNAs expressed in fungal microsporidia genomes are important for elucidating the mech…
View article: A Matrix Metalloproteinase Mediates Tracheal Development in Bombyx mori
A Matrix Metalloproteinase Mediates Tracheal Development in Bombyx mori Open
The trachea of insects is a tubular epithelia tissue that transports oxygen and other gases. It serves as a useful model for the studying of the cellular and molecular events involved in epithelial tube formation. Almost all of the extrace…
View article: BmFoxO Gene Regulation of the Cell Cycle Induced by 20-Hydroxyecdysone in BmN-SWU1 Cells
BmFoxO Gene Regulation of the Cell Cycle Induced by 20-Hydroxyecdysone in BmN-SWU1 Cells Open
Ecdysteroid titer determines the state of the cell cycle in silkworm (Bombyxmori) metamorphosis. However, the mechanism of this process is unclear. In this study, we demonstrated that the BmFoxO gene participates in the regulation of the c…
View article: CRISPR/Cas12a Mediated Genome Editing Enhances Bombyx mori Resistance to BmNPV
CRISPR/Cas12a Mediated Genome Editing Enhances Bombyx mori Resistance to BmNPV Open
CRISPR/Cas12a (Cpf1) is a single RNA-guided endonuclease that provides new opportunities for targeted genome engineering through the CRISPR/Cas9 system. Only AsCas12a has been developed for insect genome editing, and the novel Cas12a ortho…
View article: CRISPR/Cpf1 mediated genome editing enhances<i>Bombyx mori</i>resistance to BmNPV
CRISPR/Cpf1 mediated genome editing enhances<i>Bombyx mori</i>resistance to BmNPV Open
CRISPR/Cas12a (Cpf1) is a single RNA-guided endonuclease that provides new opportunities for targeted genome engineering through the CRISPR/Cas9 system. Only AsCpf1 have been developed for insect genome editing, and the novel Cas12a orthol…
View article: Construction and characterization of a synthetic Baculovirus-inducible 39K promoter
Construction and characterization of a synthetic Baculovirus-inducible 39K promoter Open
In summary, we constructed a novel, synthetic, and highly efficient biological tool, namely, a virus-inducible 39 K promoter, which provides endless possibilities for future research on gene function, gene therapy, and pest control in gene…
View article: A Multiplex CRISPR/Cas9 System for Use as an Anti-BmNPV Therapeutic
A Multiplex CRISPR/Cas9 System for Use as an Anti-BmNPV Therapeutic Open
Clustered regularly interspaced short palindromic repeats/associated protein 9 nuclease (CRISPR/Cas9) technology guided by a single-guide RNA (sgRNA) has recently opened a new avenue for antiviral therapy. A unique capability of the CRISPR…
View article: Construction and Characterization of a Synthetic Baculovirus-inducible 39K Promoter
Construction and Characterization of a Synthetic Baculovirus-inducible 39K Promoter Open
The low expression activity and specificity of natural promoters limit the applications of genetic engineering. To construct a highly efficient synthetic inducible promoter in the Bombyx mori (Lepidoptera), we analyzed the regulatory eleme…
View article: Excision of Nucleopolyhedrovirus Form Transgenic Silkworm Using the CRISPR/Cas9 System
Excision of Nucleopolyhedrovirus Form Transgenic Silkworm Using the CRISPR/Cas9 System Open
The CRISPR/Cas9-mediated genome engineering has been shown to efficiently suppress infection by disrupting genes of the pathogen. We recently constructed transgenic lines expressing CRISPR/Cas9 and the double sgRNA target Bombyx mori nucle…
View article: Bombyx mori Nuclear Polyhedrosis Virus (BmNPV) Induces Host Cell Autophagy to Benefit Infection
Bombyx mori Nuclear Polyhedrosis Virus (BmNPV) Induces Host Cell Autophagy to Benefit Infection Open
Bombyx mori nuclear polyhedrosis virus (BmNPV) is an important pathogen of silkworms. Despite extensive studies in recent decades, the interaction between BmNPV and host cells is still not clearly understood. Autophagy is an intrinsic inna…
View article: Comparative transcriptome profiling of a thermal resistant vs. sensitive silkworm strain in response to high temperature under stressful humidity condition
Comparative transcriptome profiling of a thermal resistant vs. sensitive silkworm strain in response to high temperature under stressful humidity condition Open
Thermotolerance is important particularly for poikilotherms such as insects. Understanding the mechanisms by which insects respond to high temperatures can provide insights into their adaptation to the environment. Therefore, in this study…
View article: Identification and characterization of the BmCyclin L1-BmCDK11A/B complex in relation to cell cycle regulation
Identification and characterization of the BmCyclin L1-BmCDK11A/B complex in relation to cell cycle regulation Open
Cyclin proteins are the key regulatory and activity partner of cyclin-dependent kinases (CDKs), which play pivotal regulatory roles in cell cycle progression. In the present study, we identified a Cyclin L1 and 2 CDK11 2 CDK11 splice varia…
View article: Oligomerization of Baculovirus LEF-11 Is Involved in Viral DNA Replication
Oligomerization of Baculovirus LEF-11 Is Involved in Viral DNA Replication Open
We have previously reported that baculovirus Bombyx mori nucleopolyhedrovirus (BmNPV) late expression factor 11 (lef-11) is associated with viral DNA replication and have demonstrated that it potentially interacts with itself; however, whe…