Pangzhou Chen
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View article: Celecoxib pretreatment and nab-paclitaxel-associated acute pain syndrome in patients with breast cancer: a prospective, non-randomized controlled clinical study
Celecoxib pretreatment and nab-paclitaxel-associated acute pain syndrome in patients with breast cancer: a prospective, non-randomized controlled clinical study Open
Background: Taxane-associated acute pain syndrome (T-APS) is a frequent adverse effect in breast cancer patients undergoing nab-paclitaxel, affecting treatment adherence and quality of life (QoL). We analyzed the effectiveness of preventat…
View article: The Dual Roles of Circular RNAs in Breast Cancer Distant Metastasis and Their Clinical Applications
The Dual Roles of Circular RNAs in Breast Cancer Distant Metastasis and Their Clinical Applications Open
Circular RNAs (circRNAs) are emerging as crucial regulators of the progression and metastasis of breast cancer. This review examines the dual roles of circRNAs, which act as both oncogenes and tumor suppressors, in breast cancer metastasis…
View article: Clinical approaches to overcome PARP inhibitor resistance
Clinical approaches to overcome PARP inhibitor resistance Open
PARP inhibitors have profoundly changed treatment options for cancers with homologous recombination repair defects, especially those carrying BRCA1/2 mutations. However, the development of resistance to these inhibitors presents a signific…
View article: CircRNAs: a novel potential strategy to treat breast cancer
CircRNAs: a novel potential strategy to treat breast cancer Open
Breast cancer is among the most prevalent malignant tumors worldwide, with triple-negative breast cancer (TNBC) being the most aggressive subtype and lacking effective treatment options. Circular RNAs (circRNAs) are noncoding RNAs that pla…