Pankaj Sah
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View article: Application of Organic Light-Emitting Diodes and Photodiodes in Optical Control and Detection of Neuronal Activity
Application of Organic Light-Emitting Diodes and Photodiodes in Optical Control and Detection of Neuronal Activity Open
Optical techniques to study neuronal activity have greatly advanced the field of neuroscience over recent decades. Multichannel silicon-based recording probes combined with optical fibers allow for simultaneous recording and manipulation o…
View article: Modulation of pedunculopontine input to the basal ganglia relieves motor symptoms in Parkinsonian mice
Modulation of pedunculopontine input to the basal ganglia relieves motor symptoms in Parkinsonian mice Open
Locomotion, the ability to move, is driven by central pattern generators in the spinal cord. However, its initiation, selection of gait and arrest are controlled by command centers in the brain stem of which the best understood is the mese…
View article: Imaging Findings in Alagille Syndrome - A Case Report with literature review
Imaging Findings in Alagille Syndrome - A Case Report with literature review Open
Alagille syndrome (AGS)is a rare disease with autosomal dominant inheritance and involves mutation of JAG 1(90%) and NOTCH 2(1-2%). The syndrome affects multiple systems, including the liver, eye, Vertebra, and cardiac, and has peculiar fa…
View article: Solution‐Processed Ternary Organic Photodetectors with Ambipolar Small‐Bandgap Polymer for Near‐Infrared Sensing
Solution‐Processed Ternary Organic Photodetectors with Ambipolar Small‐Bandgap Polymer for Near‐Infrared Sensing Open
Organic photodetectors (OPDs) detecting light in the near‐infrared (NIR) range from 900 to 1200 nm offer numerous applications in biomedical imaging and health monitoring. However, an ultra‐low bandgap of the electron donor compound requir…
View article: 40-Hz optogenetic stimulation rescues functional synaptic plasticity after stroke
40-Hz optogenetic stimulation rescues functional synaptic plasticity after stroke Open
Evoked brain oscillations in the gamma range have been shown to assist in stroke recovery. However, the causal relationship between evoked oscillations and neuroprotection is not well understood. We have used optogenetic stimulation to inv…
View article: A qualitative exploration of expert perspectives on applying the science of learning to higher education
A qualitative exploration of expert perspectives on applying the science of learning to higher education Open
Amid the constant change in higher education, a clear-eyed focus on the mission of higher education to support student learning is critical. Supporting student success, in turn, needs to emphasise rigorous evidence about what matters most …
View article: Locating causal hubs of memory consolidation in spontaneous brain network in male mice
Locating causal hubs of memory consolidation in spontaneous brain network in male mice Open
Memory consolidation after learning involves spontaneous, brain-wide network reorganization during rest and sleep, but how this is achieved is still poorly understood. Current theory suggests that the hippocampus is pivotal for this reshap…
View article: Reverse engineering information processing in lateral amygdala during auditory tones
Reverse engineering information processing in lateral amygdala during auditory tones Open
Learning in the mammalian lateral amygdala (LA) during auditory fear conditioning (tone - foot shock pairing), one form of associative learning, requires N-methyl-D-aspartate (NMDA) receptor-dependent plasticity. Despite this fact being kn…
View article: A Novel Biophysical Model for the Generation of Sharp Wave Ripples in CA1 Hippocampus
A Novel Biophysical Model for the Generation of Sharp Wave Ripples in CA1 Hippocampus Open
Synchronous activities among neurons in the brain generate emergent network oscillations such as the hippocampal Sharp-wave ripples (SPWRs) that facilitate information processing during memory formation. However, how neurons and circuits a…
View article: The PPN and motor control: Preclinical studies to deep brain stimulation for Parkinson’s disease
The PPN and motor control: Preclinical studies to deep brain stimulation for Parkinson’s disease Open
The pedunculopontine nucleus (PPN) is the major part of the mesencephalic locomotor region, involved in the control of gait and locomotion. The PPN contains glutamatergic, cholinergic, and GABAergic neurons that all make local connections,…
View article: Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation
Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation Open
The deep brain stimulation (DBS) Think Tank X was held on August 17–19, 2022 in Orlando FL. The session organizers and moderators were all women with the theme women in neuromodulation . Dr. Helen Mayberg from Mt. Sinai, NY was the keynote…
View article: Isolated Inflammatory Necrosis of the Falciform Ligament: A Case Report with Review of Literature
Isolated Inflammatory Necrosis of the Falciform Ligament: A Case Report with Review of Literature Open
Inflammatory necrosis of the falciform ligament is an extremely rare cause of acute right upper quadrant pain. Due to overlapping symptoms with pathologies affecting the gall bladder and liver, this poses a diagnostic challenge with limite…
View article: Back Cover Image
Back Cover Image Open
This cover (DOI: 10.1002/inf2.12345 ) shows a multifunctional TPA‐azaBODIPY‐TPA small molecule with superior optoelectronic and photophysical properties. Material is shown to function as an efficient hole transport layer in perovskite sola…
View article: Versatile <scp>aza‐BODIPY</scp>‐based <scp>low‐bandgap</scp> conjugated small molecule for light harvesting and <scp>near‐infrared</scp> photodetection
Versatile <span>aza‐BODIPY</span>‐based <span>low‐bandgap</span> conjugated small molecule for light harvesting and <span>near‐infrared</span> photodetection Open
The versatile nature of organic conjugated materials renders their flawless integration into a diverse family of optoelectronic devices with light‐harvesting, photodetection, or light‐emitting capabilities. Classes of materials that offer …
View article: Locating causal hubs of memory consolidation in spontaneous brain network
Locating causal hubs of memory consolidation in spontaneous brain network Open
SUMMARY Memory consolidation after learning involves spontaneous, brain-wide network reorganization during rest and sleep, but how this is achieved is still poorly understood. Current theory suggests that the hippocampus is pivotal for res…
View article: Changes in pallidal neural activity following long-term symptom improvement from botulinum toxin treatment in DYT6 dystonia: a case report
Changes in pallidal neural activity following long-term symptom improvement from botulinum toxin treatment in DYT6 dystonia: a case report Open
Background The globus pallidus internus is the main target for the treatment of dystonia by deep brain stimulation. Unfortunately, for some genetic etiologies, the therapeutic outcome of dystonia is less predictable. In particular, therape…
View article: Hippocampus–Prefrontal Coupling Regulates Recognition Memory for Novelty Discrimination
Hippocampus–Prefrontal Coupling Regulates Recognition Memory for Novelty Discrimination Open
Recognition memory provides the ability to distinguish familiar from novel objects and places, and is important for recording and updating events to guide appropriate behavior. The hippocampus (HPC) and medial prefrontal cortex (mPFC) have…
View article: Microcircuit mechanisms for the generation of sharp-wave ripples in the basolateral amygdala: A role for chandelier interneurons
Microcircuit mechanisms for the generation of sharp-wave ripples in the basolateral amygdala: A role for chandelier interneurons Open
Synchronized activity in neural circuits, detected as oscillations in the extracellular field potential, has been associated with learning and memory. Neural circuits in the basolateral amygdala (BLA), a mid-temporal lobe structure, genera…
View article: Inhibitory Circuits in the Basolateral Amygdala in Aversive Learning and Memory
Inhibitory Circuits in the Basolateral Amygdala in Aversive Learning and Memory Open
Neural circuits in the basolateral amygdala (BLA) play a pivotal role in the learning and memory formation, and processing of emotionally salient experiences, particularly aversive ones. A diverse population of GABAergic neurons present in…
View article: Selective Ablation of BDNF from Microglia Reveals Novel Roles in Self-Renewal and Hippocampal Neurogenesis
Selective Ablation of BDNF from Microglia Reveals Novel Roles in Self-Renewal and Hippocampal Neurogenesis Open
Microglia, the resident immune cells of the CNS, have emerged as key regulators of neural precursor cell activity in the adult brain. However, the microglia-derived factors that mediate these effects remain largely unknown. In the present …
View article: A randomised, double-blind, sham-controlled trial of deep brain stimulation of the bed nucleus of the stria terminalis for treatment-resistant obsessive-compulsive disorder
A randomised, double-blind, sham-controlled trial of deep brain stimulation of the bed nucleus of the stria terminalis for treatment-resistant obsessive-compulsive disorder Open
Deep brain stimulation (DBS) is a promising treatment for severe, treatment-resistant obsessive-compulsive disorder (OCD). Here, nine participants (four females, mean age 47.9 ± 10.7 years) were implanted with DBS electrodes bilaterally in…
View article: A midbrain - thalamus - cortex circuit reorganizes cortical dynamics to initiate planned movement
A midbrain - thalamus - cortex circuit reorganizes cortical dynamics to initiate planned movement Open
Motor behaviors are often planned long before execution, but only released after specific sensory events. Planning and execution are each associated with distinct patterns of motor cortex activity. Key questions are how these dynamic activ…