Panpan Ma
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View article: The Association and diagnostic value between Maternal Serum Placental Markers and Placenta Previa
The Association and diagnostic value between Maternal Serum Placental Markers and Placenta Previa Open
The elevated maternal serum levels of Free β-hCG and AFP may be associated with placenta previa. The combined detection of maternal serum markers in the early and mid-trimesters has better diagnostic value for predicting placenta previa th…
View article: Serum bile acid and unsaturated fatty acid profiles of non-alcoholic fatty liver disease in type 2 diabetic patients
Serum bile acid and unsaturated fatty acid profiles of non-alcoholic fatty liver disease in type 2 diabetic patients Open
BACKGROUND The understanding of bile acid (BA) and unsaturated fatty acid (UFA) profiles, as well as their dysregulation, remains elusive in individuals with type 2 diabetes mellitus (T2DM) coexisting with non-alcoholic fatty liver disease…
View article: A novel microRNA miR-4433a-3p as a potential diagnostic biomarker for lung adenocarcinoma
A novel microRNA miR-4433a-3p as a potential diagnostic biomarker for lung adenocarcinoma Open
miR-4433a-3p may serve as a biomarker for the early diagnosis of lung adenocarcinoma and monitoring of therapeutic effects.
View article: Comparative Colloidal Stability of Commercial Amphotericin B Nanoformulations Using Dynamic and Static Multiple Light Scattering Techniques [Corrigendum]
Comparative Colloidal Stability of Commercial Amphotericin B Nanoformulations Using Dynamic and Static Multiple Light Scattering Techniques [Corrigendum] Open
[This corrects the article DOI: 10.2147/IJN.S387681.].
View article: Analysis of spinal muscular atrophy carrier screening results in 32,416 pregnant women and 7,231 prepregnant women
Analysis of spinal muscular atrophy carrier screening results in 32,416 pregnant women and 7,231 prepregnant women Open
Objectives Spinal muscular atrophy (SMA) is an autosomal recessive disease that is one of the most common in childhood neuromuscular disorders. Our screenings are more meaningful programs in preventing birth defects, providing a significan…
View article: Comparative transcriptome analysis reveals the adaptive mechanisms of halophyte Suaeda dendroides encountering high saline environment
Comparative transcriptome analysis reveals the adaptive mechanisms of halophyte Suaeda dendroides encountering high saline environment Open
Suaeda dendroides , a succulent euhalophyte of the Chenopodiaceae family, intermittently spread around northern Xinjiang, China, has the ability to grow and develop in saline and alkali environments. The objective of this study was therefo…
View article: Transcriptome Analysis Reveals Key Genes Involved in the Response of Pyrus betuleafolia to Drought and High-Temperature Stress
Transcriptome Analysis Reveals Key Genes Involved in the Response of Pyrus betuleafolia to Drought and High-Temperature Stress Open
Drought and high-temperature stress are the main abiotic stresses that alone or simultaneously affect the yield and quality of pears worldwide. However, studies on the mechanisms of drought or high-temperature resistance in pears remain el…
View article: Immune skeletal dysplasia with neurodevelopmental abnormalities caused by a novel variant of <i>EXTL3</i> gene in a Chinese family
Immune skeletal dysplasia with neurodevelopmental abnormalities caused by a novel variant of <i>EXTL3</i> gene in a Chinese family Open
Background Immune skeletal dysplasia with neurodevelopmental abnormalities (ISDNA) is an extremely rare, autosomal recessive genetic disorder characterized by various skeletal abnormalities, neurodevelopmental deficits, and abnormal immune…
View article: High-Quality Genome Resource of <i>Nothophoma quercina</i> Causing Brown Spot Disease in Pears
High-Quality Genome Resource of <i>Nothophoma quercina</i> Causing Brown Spot Disease in Pears Open
Brown spot, a serious disease caused by Nothophoma quercina, results in small, brown, round-to-oval lesions on the leaves and is a major concern in the pear industry. We previously reported a new pathogenic strain NqHH of Nothophoma querci…
View article: CCDC 2248363: Experimental Crystal Structure Determination
CCDC 2248363: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2231851: Experimental Crystal Structure Determination
CCDC 2231851: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Judicial and legislative practice and related suggestions on off-label drug use in China
Judicial and legislative practice and related suggestions on off-label drug use in China Open
Background Off-label drug use exists widely in medical practice and is also an area which easily triggers controversy between patients and medical institutions. Previous studies have identified the reasons why off-label drug use long exist…
View article: New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties
New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties Open
This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal. For that purpose, two new 1:1 cocrystals, namely lidocaine:dl-m…
View article: PsA inhibits the development of bovine embryos through epigenetic and oxidative stress
PsA inhibits the development of bovine embryos through epigenetic and oxidative stress Open
OBJECTIVE Histone deacetylases (HDACs) are the key regulators involved in the process of embryo development and tumor progression and are often dysregulated in numerous disordered cells, including tumor cells and somatic cell nuclear trans…
View article: High expression of peroxisomal D-bifunctional protein in cytosol regulates apoptosis and energy metabolism of hepatocellular carcinoma cells via PI3K/AKT pathway.
High expression of peroxisomal D-bifunctional protein in cytosol regulates apoptosis and energy metabolism of hepatocellular carcinoma cells via PI3K/AKT pathway. Open
Peroxisomal D-bifunctional protein (DBP) is an indispensable enzyme of the fatty acid β-oxidation in the peroxisome of humans. However, the role of DBP in oncogenesis is poorly understood. Our previous studies have demonstrated that DBP ov…
View article: CCDC 2232113: Experimental Crystal Structure Determination
CCDC 2232113: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Comparative Colloidal Stability of Commercial Amphotericin B Nanoformulations Using Dynamic and Static Multiple Light Scattering Techniques
Comparative Colloidal Stability of Commercial Amphotericin B Nanoformulations Using Dynamic and Static Multiple Light Scattering Techniques Open
To the best of our knowledge, this study is the first to compare the colloidal stability of commercial AmB nanoformulations. These findings will provide useful information not only to inform the clinical use of available AmB nanoformulatio…
View article: Establishment of a modified Kyoto classification scoring model and its significance in the diagnosis of Helicobacter pylori current infection
Establishment of a modified Kyoto classification scoring model and its significance in the diagnosis of Helicobacter pylori current infection Open
The modified Kyoto classification scoring model improved the accuracy of endoscopic determination of HP current infection and has clinical application potential in the Chinese population.
View article: Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy
Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy Open
We report the formulation, characterization, colloidal stability, and in vitro efficiency of Fisetin nanocrystals stabilized by poloxamer P407. Such nanocrystals present a nanometer scale (148.6 ± 1.1 nm) and a high homogeneity (polydisper…
View article: Neuroendocrine tumour of the descending part of the duodenum complicated with schwannoma: A case report
Neuroendocrine tumour of the descending part of the duodenum complicated with schwannoma: A case report Open
Immunohistochemical results showed that the mass was a rare NET with neurilemmoma.
View article: Porcine Intestinal Organoids: Overview of the State of the Art
Porcine Intestinal Organoids: Overview of the State of the Art Open
The intestinal tract is a crucial part of the body for growth and development, and its dysregulation can cause several diseases. The lack of appropriate in vitro models hampers the development of effective preventions and treatments agains…
View article: The Mutation Analysis of the AMT Gene in a Chinese Family With Nonketotic Hyperglycinemia
The Mutation Analysis of the AMT Gene in a Chinese Family With Nonketotic Hyperglycinemia Open
Background: Nonketotic hyperglycinemia is a metabolic disease with autosomal recessive inheritance due to the glycine cleavage system (GCS) defect leading to the accumulation of glycine that causes severe and fatal neurological symptoms in…