Explanipedia

Pancreatitis Preceding the Diagnosis of IBD in Children: A Retrospective Observational Study Open

Lorenzo D’Antonio, Valerio Balassone, Federico Alghisi, Chiara Imondi, Francesca Rea , et al. · 2025

Background: Pancreatic involvement in inflammatory bowel diseases (IBD) is relatively common and includes a range of conditions, such as acute pancreatitis (AP), chronic pancreatitis (CP), autoimmune pancreatitis (AIP), and pancreatic exoc…

Innovative endoscopic alternatives for the conservative management of recurrent/refractory esophageal strictures in children: A case series Open

Chiara Imondi, Manuela Bartoli, Filippo Torroni, Simona Faraci, Tamara Caldaro , et al. · 2025

BACKGROUND Refractory esophageal strictures (ES) are defined an anatomical restriction without an active endoscopic inflammation resulting in dysphagia after a minimum of five seriated dilatations in a 4-weeks interval. Recurrent ES (REES)…

Eosinophilic esophagitis in children and adolescents: a clinical practice guideline Open

Salvatore Oliva, Serena Arrigo, Matteo Bramuzzo, Fabio Cisarò, Emanuele Dabizzi , et al. · 2025

Endoscopy and noninvasive tests in pediatric disorders of gut–brain interaction: A multicenter retrospective study of the Italian Society of Pediatric Gastroenterology, Hepatology, and Nutrition Open

Mattia Spatuzzo, Chiara Imondi, Paola De Angelis, Fortunata Civitelli, Valentina Giorgio , et al. · 2025

Objectives Disorders of gut–brain interactions (DGBIs) are highly prevalent in pediatric gastroenterology and often lead to the use of invasive and noninvasive diagnostic tests, despite the guidance provided by the Rome IV criteria. Rome I…

Management of oesophageal strictures in inherited epidermolysis bullosa: a clinical practice guideline Open

May El Hachem, Tamara Caldaro, Irene Lara‐Corrales, Elena Pope, Rosie Jones , et al. · 2025

Inherited epidermolysis bullosa (EB) is a group of rare and complex genetic disorders characterized by fragility of the skin and mucous membranes. Specifically, the gastrointestinal tract is commonly involved with a range of complications,…

Risk scores for choledocholithiasis perform poorly in patients with hemolytic diseases: a PEDI database report Open

Jennifer Thompson, Wenly Ruan, Douglas S. Fishman, Matthew J. Giefer, Kyung Mo Kim , et al. · 2025

Patients with hemolytic diseases are at increased risk for gallstone-related complications. Modified scoring systems have been developed to assess which pediatric patients would benefit from endoscopic retrograde cholangiopancreatography (…

Clinical Presentations of Celiac Disease: Experience of a Single Italian Center Open

Chiara Maria Trovato, Francesca Ferretti, Anna Pia Delli Bovi, Grazia Maria Elefante, Monica Ancinelli , et al. · 2024

Background/Objectives: In Italy, the prevalence of celiac disease (CeD) among children exceeds 1.5% and has steadily increased with a linear trend over the past 25 years. The clinical presentation is heterogenous and a change in onset symp…

The 1st EoETALY Consensus on the Diagnosis and Management of Eosinophilic Esophagitis–Current Treatment and Monitoring Open

Nicola de Bortoli, Pierfrancesco Visaggi, Roberto Penagini, Bruno Annibale, Federica Baiano Svizzero , et al. · 2024

The present document constitutes Part 2 of the EoETALY Consensus Statements guideline on the diagnosis and management of eosinophilic esophagitis (EoE) developed by experts in the field of EoE across Italy (i.e., EoETALY Consensus Group). …

CFTR function is impaired in a subset of patients with pancreatitis carrying rare CFTR variants Open

Dora Angyal, Karina Kleinfelder, Fabiana Ciciriello, Tessa A. Groeneweg, Giulia De Marchi , et al. · 2024

CFTR function is impaired in a subset of pancreatitis patients carrying CFTR variants. Mutations outside the CFTR locus may contribute to the anion transport defect. Bioassays on patient-derived intestinal tissue and organoids can be used …

The 1st EoETALY Consensus on the Diagnosis and Management of Eosinophilic Esophagitis – Definition, Clinical Presentation and Diagnosis Open

Nicola de Bortoli, Pierfrancesco Visaggi, Roberto Penagini, Bruno Annibale, Federica Baiano Svizzero , et al. · 2024

Vernal keratoconjunctivitis and eosinophilic esophagitis: A rare combination? Open

Maria Cristina Artesani, Sara Urbani, Carla Riccardi, Mariacristina Esposito, Paola De Angelis , et al. · 2024

Vernal keratoconjunctivitis (VKC) is a bilateral ocular inflammatory disease with a conjunctival and corneal involvement and typical onset during childhood. Eosinophilic esophagitis (EoE) is a chronic disease characterized by eosinophilic …

Short-term Psychodynamic Psychotherapy in Addition to Standard Medical Therapy Increases Clinical Remission in Adolescents and Young Adults with Inflammatory Bowel Disease: a Randomised Controlled Trial Open

Francesco Milo, Chiara Imondi, Carmen D’Amore, Giulia Angelino, D. Knafelz , et al. · 2023

Background Inflammatory bowel diseases [IBD] are chronic and pervasive conditions of the gastrointestinal tract with a rising incidence in paediatric and young adult populations. Evidence suggests that psychological disorders might be asso…

Neurological impairment and malnutrition in children: The role of home enteral nutrition in real life Open

Antonella Diamanti, Teresa Capriati, Antonella Mosca, Chiara Maria Trovato, Francesca Laureti , et al. · 2023

Objective Recent decades have brought an increased survival of children with Neurologic Impairment (NI) but malnutrition and digestive comorbidity remain important challenges to face. We designed the present study to assess the course of n…

New frontiers for therapeutic endoscopic ultrasound in children Open

Valerio Balassone, Simona Faraci, Chiara Imondi, Paola De Angelis, Tamara Caldaro , et al. · 2023

Therapeutic endoscopic ultrasound is a well-established tool for several gastrointestinal disorders in adults. Diffusion in children is still limited but it can represent an effective, non-invasive option. A selection of relevant clinical …

Endoscopic ultrasound-guided gastrojejunostomy with lumen-apposing metal stent in a boy with neurological impairment requiring jejunal feeding Open

Valerio Balassone, Francesco Maria Di Matteo, Chiara Imondi, Teresa Capriati, Paola De Angelis · 2022

Video 1EUS-guided, LAMS-assisted gastrojejunostomy for re-routing a PEGJ tube in neurologically impaired children.

SARS-COV2 and Eosinophilic Esophagitis: a first case. Open

Maurizio Mennini, Francesca Rea, Monica Malamisura, Carla Riccardi, Luigi Dall’Oglio , et al. · 2022

Impact of COVID-19 pandemic on pediatric endoscopy: A multicenter study on behalf of the SIGENP Endoscopy Working Group Open

Sara Renzo, Luca Scarallo, Luca Maria Antoniello, Matteo Bramuzzo, Andrea Chiaro , et al. · 2022

Direct visualization of biliary stump polyp in a boy with recurrent pancreatitis after surgery for pancreatobiliary maljunction associated with choledocal cyst Open

Valerio Balassone, Chiara Imondi, Tamara Caldaro, Paola De Angelis, Luigi Dall’Oglio · 2021

Long-term outcomes of intraoperative radiation therapy during radical prostatectomy for high-risk prostate cancer Open

G. Marchioro, Davide Perri, M. Zacchero, F. Poletti, Carlotta Palumbo , et al. · 2021

Unfavourable outcomes following ureteroscopy and Ho:YAG laser lithotripsy for the treatment of ureteral/renal stones at a single tertiary-referral centre Open

Eugenio Ventimiglia, Luca Villa, Michele De Angelis, Paola De Angelis, Christian Corsini , et al. · 2021

SARS-COV2 and eosinophilic esophagitis: a first case Open

Maurizio Mennini, Francesca Rea, Carla Riccardi, Paola De Angelis, Renato Tambucci · 2021

Since it was initially reported on 31st December 2019, the disease known as coronavirus disease (COVID-19) has spread across the globe, and Italy was the first European country to face the consequences. The clinical and psychological impac…

Eosinophilic Esophagitis and Microbiota: State of the Art Open

Maurizio Mennini, Renato Tambucci, Carla Riccardi, Francesca Rea, Paola De Angelis , et al. · 2021

Eosinophilic esophagitis (EoE) is a chronic, food-triggered, immune-mediated disease of the oesophagus, clinically characterized by symptoms referred to oesophagal dysfunction, and histologically defined by an eosinophil productive inflamm…

How did the COVID-19 pandemic change the practice of Paediatric Endoscopists in Europe? Open

Ilektra Athiana, Corinne Légeret, Patrick Bontems, Luigi Dall’Oglio, Paola De Angelis , et al. · 2020

Background: As endoscopists are at risk to get infected by the novel Coronavirus SARS-CoV-2 during endoscopic procedures, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) published recommendations re…

Mo1988 THE PEDIATRIC ENDOSCOPY PRACTICE IN EUROPE: PRELIMINARY RESULTS OF A WEB-BASED SURVEY ON BEHALF OF THE ENDOSCOPY SPECIAL INTEREST GROUP OF EUROPEAN SOCIETY OF GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION (ESPGHAN) Open

Salvatore Oliva, Jorge Amil Dias, Fadhel Alateeqi, Rana Bitar, Patrick Bontems , et al. · 2020

Peroral endoscopic myotomy in a child with Triple A syndrome (Allgrove syndrome) Open

Riccardo Rizzo, Valerio Balassone, Filippo Torroni, Paola De Angelis, Luigi Dall’Oglio · 2020

Natural orifice endoluminal technique (NOEL) for the management of congenital duodenal membranes Open

Jonathan Goring, Sara Isoldi, Shishu Sharma, Filippo Torroni, Sean Marven , et al. · 2019

Autologous Intestinal Reconstructive Surgery in the Management of Total Intestinal Aganglionosis Open

Fabio Fusaro, Francesco Morini, Annika Mutanen, Paola De Angelis, Roberto Tambucci , et al. · 2019

Objectives: Total/near total intestinal aganglionosis (TIA/NTIA) is the most uncommon and life‐threatening form of Hirschsprung disease (HD). The management of TIA/NTIA is challenging and the role of autologous intestinal reconstructive (A…

Respiratory problems in children with esophageal atresia and tracheoesophageal fistula Open

Federica Porcaro, Laura Valfrè, Lelia Rotondi Aufiero, Luigi Dall’Oglio, Paola De Angelis , et al. · 2017

Anastomotic ulcers in short bowel syndrome: New suggestions from a multidisciplinary approach Open

Fabio Fusaro, Renato Tambucci, Erminia Romeo, Pietro Bagolan, Luigi Dall’Oglio , et al. · 2017

Anastomotic Strictures after Esophageal Atresia Repair: Incidence, Investigations, and Management, Including Treatment of Refractory and Recurrent Strictures Open

Renato Tambucci, Giulia Angelino, Paola De Angelis, Filippo Torroni, Tamara Caldaro , et al. · 2017

Improved surgical techniques, as well as preoperative and postoperative care, have dramatically changed survival of children with esophageal atresia (EA) over the last decades. Nowadays, we are increasingly seeing EA patients experiencing …

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