Paola Faverio
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View article: A novel RTEL1 nonsense variant in a case of familial pulmonary fibrosis: clinical description and genetic implications
A novel RTEL1 nonsense variant in a case of familial pulmonary fibrosis: clinical description and genetic implications Open
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease, often linked to telomere-related gene (TRG) mutations in familial forms. Telomere biology disorders can also manifest with systemic features such as bone marro…
View article: Awareness of respiratory syncytial virus and other respiratory disease vaccines among healthcare professionals and their patients in Italy: Insights from a literature review and a web-based survey
Awareness of respiratory syncytial virus and other respiratory disease vaccines among healthcare professionals and their patients in Italy: Insights from a literature review and a web-based survey Open
Respiratory syncytial virus (RSV) causes respiratory infections across all ages, with an increasingly recognized burden in older adults, particularly those with comorbidities. Despite the recent licensure of RSV vaccines, awareness of RSV …
View article: Acetazolamide Plus Atomoxetine for Obesity Hypoventilation Syndrome Treatment
Acetazolamide Plus Atomoxetine for Obesity Hypoventilation Syndrome Treatment Open
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View article: A Novel Rtel1 Nonsense Variant in a Case of Familial Pulmonary Fibrosis
A Novel Rtel1 Nonsense Variant in a Case of Familial Pulmonary Fibrosis Open
Background Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease, often linked to telomere-related gene (TRG) mutations in familial forms. Case presentation We report a 72-year-old woman with a family history of pu…
View article: Prevalence and types of treatable traits in bronchiectasis: a multicentre, cross-sectional study
Prevalence and types of treatable traits in bronchiectasis: a multicentre, cross-sectional study Open
View article: How do climate conditions and urbanisation impact nontuberculous mycobacterial infections? An Italian nationwide case–control study
How do climate conditions and urbanisation impact nontuberculous mycobacterial infections? An Italian nationwide case–control study Open
Introduction Nontuberculous mycobacteria (NTM) are opportunistic pathogens primarily found in soil and water. Previous studies have linked higher population density and tropical/subtropical climates with increased NTM pulmonary disease (NT…
View article: Alteration of Lipid Metabolism in Patients with IPF and Its Association with Disease Severity and Prognosis: A Case–Control Study
Alteration of Lipid Metabolism in Patients with IPF and Its Association with Disease Severity and Prognosis: A Case–Control Study Open
The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves complex interactions between epithelial, mesenchymal, immune, and endothelial cells, often aggravated by lipid metabolism dysfunction, mitochondrial, and peroxisomal abnormal…
View article: Clinical Impact of Vaping
Clinical Impact of Vaping Open
The term ‘vaping’ refers to the use of electronic cigarettes or other devices to inhale a variety of heated and aerosolized substances. Vaping has been promoted as a less harmful and potentially oncogenic alternative to nicotine cigarettes…
View article: A rare case of bronchial stenosis in ulcerative colitis
A rare case of bronchial stenosis in ulcerative colitis Open
This case underscores the importance of early diagnosis and a multidisciplinary treatment approach to managing complex IBD-related respiratory involvement. Future research on targeted therapies and personalized management strategies is nee…
View article: Cardiovascular structural and functional parameters in idiopathic pulmonary fibrosis at disease diagnosis
Cardiovascular structural and functional parameters in idiopathic pulmonary fibrosis at disease diagnosis Open
Introduction The prevalence of cardiac and vascular fibrosis in patients with Idiopathic Pulmonary Fibrosis (IPF) has not been extensively evaluated. Aim In this study, we aimed to evaluate the heart and vessels functional and structural p…
View article: Diagnostic Management of Pediatric Bronchiectasis: A Literature Review and Clinical Examples
Diagnostic Management of Pediatric Bronchiectasis: A Literature Review and Clinical Examples Open
Background: Bronchiectasis is an often underdiagnosed chronic respiratory disease in children and adolescents. Recent international guidelines highlighted the management of bronchiectasis in pediatric patients in comparison to adults. The …
View article: Das Muster der gewöhnlichen interstitiellen Pneumonie bei rheumatischen Autoimmunerkrankungen
Das Muster der gewöhnlichen interstitiellen Pneumonie bei rheumatischen Autoimmunerkrankungen Open
Die gewöhnliche interstitielle Pneumonie (UIP) ist durch die fortschreitende Lungenparenchymveränderung gekennzeichnet, die bei verschiedenen rheumatischen Autoimmunerkrankungen (ARD), einschließlich rheumatoider Arthritis und Bindegewebse…
View article: The ‘Liaisons dangereuses’ Between Lung Cancer and Interstitial Lung Diseases: A Focus on Acute Exacerbation
The ‘Liaisons dangereuses’ Between Lung Cancer and Interstitial Lung Diseases: A Focus on Acute Exacerbation Open
Patients with interstitial lung disease (ILD) are about five times more likely to develop lung cancer than those without ILD. The presence of ILD in lung cancer patients complicates diagnosis and management, resulting in lower survival rat…
View article: Treatment of acute exacerbation in interstitial lung disease secondary to autoimmune rheumatic diseases: More questions than answers
Treatment of acute exacerbation in interstitial lung disease secondary to autoimmune rheumatic diseases: More questions than answers Open
Interstitial lung disease (ILD) is a relevant cause of morbidity and mortality in patients with autoimmune rheumatic diseases (ARDs). In the last years, an acute exacerbation (AE) - defined as an acute, clinically significant respiratory d…
View article: Cystic lung in sarcoidosis: Clinico‐radiologic characteristic and evolution
Cystic lung in sarcoidosis: Clinico‐radiologic characteristic and evolution Open
Background and Objective Sarcoidosis can manifest with atypical findings on chest computed tomography (CT). Cysts are a rare manifestation of lung sarcoidosis. The aim of the study was to describe a series of patients with cystic sarcoidos…
View article: Therapeutic Management of Bronchiectasis in Children and Adolescents: A Concise Narrative Review
Therapeutic Management of Bronchiectasis in Children and Adolescents: A Concise Narrative Review Open
Introduction: Bronchiectasis, characterized by airway dilation, mucus hypersecretion, and recurrent exacerbations, is increasingly recognized in children and adolescents. Recent guidelines from the European Respiratory Society (ERS) and Th…
View article: Questionnaires May Help Pulmonologists for Referral of Patients With IPF to a Holistic Approach
Questionnaires May Help Pulmonologists for Referral of Patients With IPF to a Holistic Approach Open
View article: Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis
Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis Open
View article: Diagnostic delay in bronchiectasis: an Italian perspective
Diagnostic delay in bronchiectasis: an Italian perspective Open
It takes ∼3.5 years to reach a diagnosis of bronchiectasis from onset of symptoms: the long patient's journey in Italy https://bit.ly/46XMWAz.
View article: Evaluation of preoperative cardiopulmonary reserve and surgical risk of patients undergoing lung cancer resection
Evaluation of preoperative cardiopulmonary reserve and surgical risk of patients undergoing lung cancer resection Open
Lung cancer represents the second most frequent neoplasm and the leading cause of neoplastic death among both women and men, causing almost 25% of all cancer deaths. Patients undergoing lung resection—both for primary and secondary tumors—…
View article: Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients
Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients Open
Background Exacerbations of COPD (ECOPD) have a major impact on patients and healthcare systems across the world. Precise estimates of the global burden of ECOPD on mortality and hospital readmission are needed to inform policy makers and …
View article: The usual Interstitial pneumonia pattern in autoimmune rheumatic diseases
The usual Interstitial pneumonia pattern in autoimmune rheumatic diseases Open
View article: Healthcare costs and resources utilization in children with difficult‐to‐control asthma treated with biologic therapies: A population‐based cohort study
Healthcare costs and resources utilization in children with difficult‐to‐control asthma treated with biologic therapies: A population‐based cohort study Open
Introduction Asthma is one of the most common diseases in children, with a variable range of severity. In recent years, treatment for severe asthma has been largely improved by the availability of targeted biologic therapies. Nevertheless,…
View article: Concurrent features of sarcoidosis and hypersensitivity pneumonitis in two patients exposed to fungal antigens
Concurrent features of sarcoidosis and hypersensitivity pneumonitis in two patients exposed to fungal antigens Open
Background Sarcoidosis and hypersensitivity pneumonitis (HP) are two distinct clinical entities that share granulomatous inflammation, although each of them has specific clinical, radiologic and pathologic profiles. Coexistence of the two …
View article: Idiopathic interstitial pneumonia in a patient with von Hippel–Lindau syndrome: a first case
Idiopathic interstitial pneumonia in a patient with von Hippel–Lindau syndrome: a first case Open
Although the mechanisms are not known, this is a case of progressive interstitial lung involvement, with a NSIP radiological pattern, evolving in pulmonary fibrosis in a patient with von Hippel-Lindau syndrome, without extrapulmonary fi…
View article: Two-year cardio-pulmonary follow-up after severe COVID-19: a prospective study
Two-year cardio-pulmonary follow-up after severe COVID-19: a prospective study Open
View article: Healthcare costs and resource utilisation in bronchiectasis, asthma and COPD
Healthcare costs and resource utilisation in bronchiectasis, asthma and COPD Open
Direct healthcare costs for patients with asthma are less than half (-52%) and for patients with COPD are 41% higher if compared to those of patients with bronchiectasis. The leading expense items in bronchiectasis are hospitalisations …
View article: Sleep-Disordered Breathing and Chronic Respiratory Infections: A Narrative Review in Adult and Pediatric Population
Sleep-Disordered Breathing and Chronic Respiratory Infections: A Narrative Review in Adult and Pediatric Population Open
Sleep-disordered breathing (SDB) comprises different diseases characterized by abnormal respiratory patterns during sleep including obstructive sleep apnea. SDB prevalence and impact in patients with chronic respiratory infections have bee…
View article: Effectiveness and economic impact of Dupilumab in asthma: a population-based cohort study
Effectiveness and economic impact of Dupilumab in asthma: a population-based cohort study Open
View article: Fibrotic or nonfibrotic interstitial lung disease in patients with primary Sjögren syndrome
Fibrotic or nonfibrotic interstitial lung disease in patients with primary Sjögren syndrome Open