Paola Finocchietto
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View article: High Salt Intake Affects Visceral Adipose Tissue Homeostasis: Beneficial Effects of GLP-1 Agonists
High Salt Intake Affects Visceral Adipose Tissue Homeostasis: Beneficial Effects of GLP-1 Agonists Open
High salt (NaCl) intake has been associated with visceral adipose tissue (VAT) dysfunction independently of its impact on blood pressure. Liraglutide (LGT), a GLP-1 agonist, could be a potential therapeutic option. We investigated the impa…
View article: Unresectable Desmoplastic Small Round Cell Tumor: A Case Report and Review of the Literature
Unresectable Desmoplastic Small Round Cell Tumor: A Case Report and Review of the Literature Open
Introduction: Desmoplastic Small Round Cell Tumor (DSRCT) is a highly aggressive and rare soft tissue sarcoma that primarily affects young males and typically presents with disseminated abdominopelvic disease. The chromosomal translocation…
View article: Comité de Gerontología. Abordaje clínico terapéutico del adulto mayor con diabetes mellitus
Comité de Gerontología. Abordaje clínico terapéutico del adulto mayor con diabetes mellitus Open
El desarrollo de la civilización se asocia con un incremento en la edad de la población. Hoy en Argentina el adulto mayor (AM: persona de 65 años o más) varón tiene una expectativa de vida de 76 años y la mujer de 80 años, lo que represent…
View article: Liraglutide improves adipose tissue remodeling and mitochondrial dynamics in a visceral obesity model induced by a high-fat diet
Liraglutide improves adipose tissue remodeling and mitochondrial dynamics in a visceral obesity model induced by a high-fat diet Open
View article: IXX Jornadas del Comité de Graduados de la Sociedad Argentina de Diabetes. Tema: “Diabetes y órganos no clásicos”. Mesa 1: Pulmón y diabetes mellitus
IXX Jornadas del Comité de Graduados de la Sociedad Argentina de Diabetes. Tema: “Diabetes y órganos no clásicos”. Mesa 1: Pulmón y diabetes mellitus Open
Las alteraciones pulmonares en personas con diabetes mellitus (DM) son cada vez más frecuentes. Su fisiopatología es compleja y multifactorial. En la siguiente revisión se expondrán las principales características de la relación entre la D…
View article: Angiotensin II Regulates Mitochondrial mTOR Pathway Activity Dependent on Acyl-CoA Synthetase 4 in Adrenocortical Cells
Angiotensin II Regulates Mitochondrial mTOR Pathway Activity Dependent on Acyl-CoA Synthetase 4 in Adrenocortical Cells Open
Two well-known protein complexes in mammalian cells, mTOR type 1 and type 2 (mTORC1/2) are involved in several cellular processes such as protein synthesis, cell proliferation, and commonly dysregulated in cancer. An acyl-CoA synthetase ty…
View article: Tumor pardo tibial como forma de presentación de un hiperparatiroidismo primario
Tumor pardo tibial como forma de presentación de un hiperparatiroidismo primario Open
La osteítis fibrosa quística es la complicación de un hiperparatiroidismo muy evolucionado. Debido a que la determinación del calcio, hormona paratiroides y vitamina D han pasado a ser estudios rutinarios, esta complicación ósea es infrecu…
View article: Inhibition of Mitochondrial Fission by Drp-1 Blockade Improves White Adipose Tissue Abnormalities in Obesity and Diabetes
Inhibition of Mitochondrial Fission by Drp-1 Blockade Improves White Adipose Tissue Abnormalities in Obesity and Diabetes Open
Background and Purpose: Obesity and Type 2 Diabetes are major causes of morbidity-mortality characterized by mitochondrial dysfunction and oxidative-nitrosative stress. Despite intensive research, the events that cause the onset and progre…
View article: Cistitis enfisematosa en un varón de 87 años
Cistitis enfisematosa en un varón de 87 años Open
Emphysematous cystitis is a complicated form of urinary tract infection, characterized by the presence of air inside the wall and in the light of the bladder, affecting more diabetics, elderly and immunosuppressed. The microorganisms that …
View article: Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells
Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells Open
View article: p66<sup>Shc</sup> Inactivation Modifies RNS Production, Regulates Sirt3 Activity, and Improves Mitochondrial Homeostasis, Delaying the Aging Process in Mouse Brain
p66<sup>Shc</sup> Inactivation Modifies RNS Production, Regulates Sirt3 Activity, and Improves Mitochondrial Homeostasis, Delaying the Aging Process in Mouse Brain Open
Programmed and damage aging theories have traditionally been conceived as stand‐alone schools of thought. However, the p66 Shc adaptor protein has demonstrated that aging‐regulating genes and reactive oxygen species (ROS) are closely inter…
View article: Fitz-Hugh-Curtis Syndrome Caused by Gonococcal Infection in a Patient with Systemic Lupus Erythematous: A Case Report and Literature Review
Fitz-Hugh-Curtis Syndrome Caused by Gonococcal Infection in a Patient with Systemic Lupus Erythematous: A Case Report and Literature Review Open
BACKGROUND Fitz-Hugh-Curtis (FHC) syndrome is a perihepatitis linked to inflammatory pelvic disease. It can be caused by Neisseria gonorrhoeae or Chlamydia trachomatis infections. FHC syndrome usually presents with pain in the right hypoch…
View article: Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB Open
Summary Background Dislipidaemia and increased levels of apolipoprotein B (apoB) in individuals with obesity are risk factors for development of cardiovascular disease (CVD). The aim of this study was to investigate the effect of weight lo…
View article: Takotsubo Myocardiopathy and Hyperthyroidism: A Case Report and Literature Review
Takotsubo Myocardiopathy and Hyperthyroidism: A Case Report and Literature Review Open
BACKGROUND Takotsubo cardiomyopathy (TM), also called stress myocardiopathy or transient left ventricular apical ballooning syndrome, is characterized by acute left ventricular dysfunction with reversible wall motion abnormalities. TM rese…
View article: Intravascular Large B Cell Lymphoma Presenting as Fever of Unknown Origin and Diagnosed by Random Skin Biopsies: A Case Report and Literature Review
Intravascular Large B Cell Lymphoma Presenting as Fever of Unknown Origin and Diagnosed by Random Skin Biopsies: A Case Report and Literature Review Open
BACKGROUND Intravascular lymphoma (IVL) is a rare lymphoproliferative disorder characterized by the proliferation of large B lymphoma cells within the lumen of small-caliber blood vessels. Clinical features are nonspecific, presenting as a…
View article: Cardiac-specific overexpression of thioredoxin 1 attenuates mitochondrial and myocardial dysfunction in septic mice
Cardiac-specific overexpression of thioredoxin 1 attenuates mitochondrial and myocardial dysfunction in septic mice Open
View article: TAFRO Syndrome in a Patient of South-American Descent
TAFRO Syndrome in a Patient of South-American Descent Open
A 31-year-old Caucasian woman of South-American descent was diagnosed with a variant of multicentric Castleman disease (MCD) that has been reported in Japan as Castleman-Kojima disease. This is a systemic inflammatory disorder known as TAF…