Paolo Fadda
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View article: MicroRNA Expression Profile in Acute Ischemic Stroke
MicroRNA Expression Profile in Acute Ischemic Stroke Open
Acute ischemic stroke with large vessel occlusion (LVO) continues to present a considerable challenge to global health, marked by substantial morbidity and mortality rates. Although definitive diagnostic markers exist in the form of neuroi…
View article: Supplementary Figure 4 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 4 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 4
View article: Supplementary Figure 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 3
View article: Supplementary Figure 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 3
View article: Supplementary Figure 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 2
View article: TABLE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
TABLE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
ESR1 locus variants and TP53 mutation associations
View article: Supplemental Tables S1-S35 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplemental Tables S1-S35 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplemental Tables S1-S35
View article: Supplementary File 1: Supplemental Table References from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary File 1: Supplemental Table References from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplemental Information: References for Supplemental Table S5
View article: FIGURE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
FIGURE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Variant selection for validation studies. Flow chart for variant prioritization for validation studies is shown for TP53 mutation associations (A) and PIK3CA mutation associations (B). Variants were first filter…
View article: FIGURE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
FIGURE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Variant selection for validation studies. Flow chart for variant prioritization for validation studies is shown for TP53 mutation associations (A) and PIK3CA mutation associations (B). Variants were first filter…
View article: Supplementary Figure 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 1
View article: FIGURE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
FIGURE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Manhattan plots for TP53 and PIK3CA discovery GxM analyses. Discovery GWAS data for 879 TP53 mutation carriers and 1,965 breast cancer cases without TP53 mutations (A), 237 cases with TP53 GOF muta…
View article: TABLE 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
TABLE 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
ESR1 variant associations in combined AFA datasets
View article: Supplementary File 1: Supplemental Table References from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary File 1: Supplemental Table References from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplemental Information: References for Supplemental Table S5
View article: Supplementary Figure 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 2
View article: Supplementary Figure 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 1
View article: TABLE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
TABLE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
ESR1 locus variants and TP53 mutation associations
View article: TABLE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
TABLE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
TP53 and PIK3CA somatic mutation frequencies
View article: FIGURE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
FIGURE 2 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Manhattan plots for TP53 and PIK3CA discovery GxM analyses. Discovery GWAS data for 879 TP53 mutation carriers and 1,965 breast cancer cases without TP53 mutations (A), 237 cases with TP53 GOF muta…
View article: Data from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Data from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype and ancestry. Emerging data suggest tumor mutation status is associated with germline variants and genetic ancestry. We aimed to identify…
View article: Supplementary Figure 4 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplementary Figure 4 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplementary Figure 4
View article: TABLE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
TABLE 1 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
TP53 and PIK3CA somatic mutation frequencies
View article: Supplemental Tables S1-S35 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Supplemental Tables S1-S35 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
Supplemental Tables S1-S35
View article: Data from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Data from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype and ancestry. Emerging data suggest tumor mutation status is associated with germline variants and genetic ancestry. We aimed to identify…
View article: TABLE 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
TABLE 3 from Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
ESR1 variant associations in combined AFA datasets
View article: Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study
Association of <i>ESR1</i> Germline Variants with <i>TP53</i> Somatic Variants in Breast Tumors in a Genome-wide Study Open
In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype and ancestry. Emerging data suggest tumor mutation status is associated with germline variants and genetic ancestry. We aimed to identify germline vari…
View article: Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits
Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits Open
Neonatal sepsis remains one of the leading causes of mortality in newborns. Several brainstem-regulated physiological processes undergo disruption during neonatal sepsis. Mechanistic knowledge gaps exist at the interplay between metabolism…
View article: MicroRNA Expression Profile in Acute Ischemic Stroke
MicroRNA Expression Profile in Acute Ischemic Stroke Open
Introduction: Acute ischemic stroke with large vessel occlusion (LVO) continues to present a considerable challenge to global health, marked by substantial morbidity and mortality rates. Although definitive diagnostic markers exist in the …
View article: Association of<i>ESR1</i>germline variants with<i>TP53</i>somatic variants in breast tumors in a genome-wide study
Association of<i>ESR1</i>germline variants with<i>TP53</i>somatic variants in breast tumors in a genome-wide study Open
Background In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype and ancestry. HER2 positive and triple negative breast cancers (TNBC) have a higher frequency of TP53 somatic mutations than other subtypes.…
View article: Glioblastoma pseudoprogression and true progression reveal spatially variable transcriptional differences
Glioblastoma pseudoprogression and true progression reveal spatially variable transcriptional differences Open