P. Villani
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View article: Comparing real-world Type 2 diabetes management with the Francophone Diabetes Society’s recommendations: using comprehensive geriatric assessment-guided medication reviews of frail older adults living with comorbid diabetes and cancer
Comparing real-world Type 2 diabetes management with the Francophone Diabetes Society’s recommendations: using comprehensive geriatric assessment-guided medication reviews of frail older adults living with comorbid diabetes and cancer Open
Purpose: Substantial clinical heterogeneity in older adults with diabetes makes therapeutic management challenging. This study compared real-world type 2 diabetes management of older outpatients who had comorbid cancer with published guide…
View article: A Systematic Review on the In Vivo Studies on Radiofrequency (100 kHz–300 GHz) Electromagnetic Field Exposure and Co-Carcinogenesis
A Systematic Review on the In Vivo Studies on Radiofrequency (100 kHz–300 GHz) Electromagnetic Field Exposure and Co-Carcinogenesis Open
In this systematic review, the potential role of in vivo RF–EMF exposure combined with the administration of well-known carcinogens in tumor promotion/progression is assessed. A total of 25 papers were included in the review. Each paper wa…
View article: Effects of radiofrequency electromagnetic field (RF-EMF) exposure on male fertility: A systematic review of experimental studies on non-human mammals and human sperm in vitro
Effects of radiofrequency electromagnetic field (RF-EMF) exposure on male fertility: A systematic review of experimental studies on non-human mammals and human sperm in vitro Open
Protocols for the systematic reviews of animal studies and of human sperm in vitro studies were published in Pacchierotti et al., 2021. The former was also registered in PROSPERO (CRD42021227729 https://www.crd.york.ac.uk/prospero/display_…
View article: Persistent COVID-19: A Case Report of an Immunocompromised Patient and a Literature Review
Persistent COVID-19: A Case Report of an Immunocompromised Patient and a Literature Review Open
Introduction: Immunocompromised patients can show prolonged shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and persistent symptoms, which is called persistent COVID-19. Case Presentation: We report a case of an im…
View article: Fate of melatonin orally administered in preterm newborns: Antioxidant performance and basis for neuroprotection
Fate of melatonin orally administered in preterm newborns: Antioxidant performance and basis for neuroprotection Open
Preterm infants cannot counteract excessive reactive oxygen species (ROS) production due to preterm birth, leading to an excess of lipid peroxidation with malondialdehyde (MDA) production, capable of contributing to brain damage. Melatonin…
View article: Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on pregnancy and birth outcomes: A systematic review of experimental studies on non-human mammals
Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on pregnancy and birth outcomes: A systematic review of experimental studies on non-human mammals Open
The protocol was published in Pacchierotti et al., 2021 and registered in PROSPERO CRD42021227746 (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=227746).
View article: Tocilizumab versus anakinra in COVID-19: results from propensity score matching
Tocilizumab versus anakinra in COVID-19: results from propensity score matching Open
Background Tocilizumab and anakinra are anti-interleukin drugs to treat severe coronavirus disease 2019 (COVID-19) refractory to corticosteroids. However, no studies compared the efficacy of tocilizumab versus anakinra to guide the choice …
View article: In Vivo Studies on Radiofrequency (100 kHz–300 GHz) Electromagnetic Field Exposure and Cancer: A Systematic Review
In Vivo Studies on Radiofrequency (100 kHz–300 GHz) Electromagnetic Field Exposure and Cancer: A Systematic Review Open
The increasing exposure of the human population to radiofrequency electromagnetic fields has increased concern about its possible health effects. The aim of this systematic review is to provide an update of the state of the research on thi…
View article: Real-world Implementation of an eHealth System Based on Artificial Intelligence Designed to Predict and Reduce Emergency Department Visits by Older Adults: Pragmatic Trial
Real-world Implementation of an eHealth System Based on Artificial Intelligence Designed to Predict and Reduce Emergency Department Visits by Older Adults: Pragmatic Trial Open
Background Frail older people use emergency services extensively, and digital systems that monitor health remotely could be useful in reducing these visits by earlier detection of worsening health conditions. Objective We aimed to implemen…
View article: General practitioners' attitude towards cooperation with other health professionals in managing patients with multimorbidity and polypharmacy: A cross-sectional study
General practitioners' attitude towards cooperation with other health professionals in managing patients with multimorbidity and polypharmacy: A cross-sectional study Open
Our study highlights disparities between GPs regarding cooperation with other professionals caring for their patients and suggests ways to improve cooperation.
View article: General practitioners' attitude towards cooperation with other health professionals in managing patients with multimorbidity and polypharmacy: A cross-sectional study
General practitioners' attitude towards cooperation with other health professionals in managing patients with multimorbidity and polypharmacy: A cross-sectional study Open
Cooperation between general practitioners (GPs) and other healthcare professionals appears to help reduce the risk of polypharmacy-related adverse events in patients with multimorbidity. To investigate GPs profiles according to their opini…
View article: Seasonality of the particle number concentration and size distribution: a global analysis retrieved from the network of Global Atmosphere Watch (GAW) near-surface observatories
Seasonality of the particle number concentration and size distribution: a global analysis retrieved from the network of Global Atmosphere Watch (GAW) near-surface observatories Open
Aerosol particles are a complex component of the atmospheric system which influence climate directly by interacting with solar radiation, and indirectly by contributing to cloud formation. The variety of their sources, as well as the multi…
View article: Centenarians in nursing homes during the COVID-19 pandemic
Centenarians in nursing homes during the COVID-19 pandemic Open
Worsening of pre-existing depression seems to be more frequent in centenarians with COVID-19 in nursing homes. This population had a higher mortality rate but a lower hospitalization rate than younger residents.
View article: Supplementary material to "Seasonality of the particle number concentration and sizedistribution: a global analysis retrieved from the network of GlobalAtmosphere Watch (GAW) near-surface observatories"
Supplementary material to "Seasonality of the particle number concentration and sizedistribution: a global analysis retrieved from the network of GlobalAtmosphere Watch (GAW) near-surface observatories" Open
Effect of cut-off diameters different from 10 nm on the calculation of Ntot -Comparison of Ntot derived from collocated MPSS and CPC measurementsThe influence on Ntot of cut-off diameters different from 10 nm (either lower or higher) was e…
View article: Acceptability of a Novel Telemedication Review for Older Adults in Nursing Homes in France: A Qualitative Study
Acceptability of a Novel Telemedication Review for Older Adults in Nursing Homes in France: A Qualitative Study Open
This study fulfilled its objective to assess pre-intervention acceptability by GP and other HP. Results provided important information about how to adapt the TMR intervention to make it more acceptable to HP who will be involved in TEM-EHP…
View article: Impact of Androgen Deprivation Therapy Associated to Conformal Radiotherapy in the Treatment of D’Amico Intermediate-/High-Risk Prostate Cancer in Older Patients
Impact of Androgen Deprivation Therapy Associated to Conformal Radiotherapy in the Treatment of D’Amico Intermediate-/High-Risk Prostate Cancer in Older Patients Open
Purpose/objective: The association of 3D Conformal External Beam Radiotherapy (3D-CEBRT) with adjuvant Androgen Deprivation Therapy (ADT) proved to treat patients with intermediate- and high-risk localized prostate cancer (IR and HR). Howe…
View article: Protocol for a Systematic Review of the in vivo Studies on Radiofrequency (100 kHz – 300 GHz) Electromagnetic Field Exposure and Cancer
Protocol for a Systematic Review of the in vivo Studies on Radiofrequency (100 kHz – 300 GHz) Electromagnetic Field Exposure and Cancer Open
Background . An Italian project aims to review the scientific literature on the possible carcinogenicity of radiofrequency (100 kHz – 300 GHz) electromagnetic field (RF-EMF) exposure. The ENEA team has to carry out a systematic review of t…
View article: <p>Medication Reconciliation Associated with Comprehensive Geriatric Assessment in Older Patients with Cancer: ChimioAge Study</p>
Medication Reconciliation Associated with Comprehensive Geriatric Assessment in Older Patients with Cancer: ChimioAge Study Open
This is one of the first studies to highlight the value in conducting CMR and a CGA simultaneously before initiating systemic treatment in older patients with cancer. These two evaluations could give oncologists decisive information to per…
View article: High Serum Vitamin B12 Levels Associated with C-Reactive Protein in Older Patients with Cancer
High Serum Vitamin B12 Levels Associated with C-Reactive Protein in Older Patients with Cancer Open
Background A Comprehensive Geriatric Assessment (CGA) has been proposed to assess prognosis and to adapt oncological care in older patients with cancer. However, few biological markers are incorporated in the CGA. Methods This comparative …