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View article: Time-restricted feeding reduces cardiovascular disease risk in obese mice
Time-restricted feeding reduces cardiovascular disease risk in obese mice Open
Disrupted feeding and fasting cycles as well as chronic high-fat diet-induced (HFD-induced) obesity are associated with cardiovascular disease risk factors. We designed studies that determined whether 2 weeks of time-restricted feeding (TR…
View article: Automatic Motorbike Stand Slider using Arduino UNO
Automatic Motorbike Stand Slider using Arduino UNO Open
View article: Comprehensive analysis of selective laser sintering (sls) in prototyping: material selection, tensile strength, hardness and densimeter evaluation
Comprehensive analysis of selective laser sintering (sls) in prototyping: material selection, tensile strength, hardness and densimeter evaluation Open
Rapid prototyping has surfaced as a conducting technology in recent moments, permitting the immediate metamorphosis of computer-aided design files into operative prototypes. This invention significantly reduces the supereminent time needed…
View article: Chronic mistimed feeding results in renal fibrosis and disrupted circadian blood pressure rhythms
Chronic mistimed feeding results in renal fibrosis and disrupted circadian blood pressure rhythms Open
Circadian disruption is a disturbance in biological timing which can occur within or between different organizational levels, ranging from molecular rhythms within specific cells to misalignment of behavioral and environmental cycles. Prev…
View article: Timed feeding aligns the adipocyte clock to optimize thermogenesis when eating a high-fat diet
Timed feeding aligns the adipocyte clock to optimize thermogenesis when eating a high-fat diet Open
View article: 430 Time restricted feeding in diet induced obesity mouse model reduces aortic stiffness and inflammatory T cells
430 Time restricted feeding in diet induced obesity mouse model reduces aortic stiffness and inflammatory T cells Open
OBJECTIVES/GOALS: Time restricted feeding (TRF) in diet induced obesity (DIO) has several health benefits, including improved metabolic rhythms and inflammation. Our lab has shown that TRF in DIO significantly reduces renal and aortic dama…
View article: Liver circadian clock disruption alters perivascular adipose tissue gene expression and aortic function in mice
Liver circadian clock disruption alters perivascular adipose tissue gene expression and aortic function in mice Open
The liver plays a central role that influences cardiovascular disease outcomes through regulation of glucose and lipid metabolism. It is recognized that the local liver molecular clock regulates some liver-derived metabolites. However, it …
View article: Timing of Food Intake Drives the Circadian Rhythm of Blood Pressure
Timing of Food Intake Drives the Circadian Rhythm of Blood Pressure Open
Timing of food intake has become a critical factor in determining overall cardiometabolic health. We hypothesized that timing of food intake entrains circadian rhythms of blood pressure (BP) and renal excretion in mice. Male C57BL/6J mice …
View article: Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain
Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain Open
The link between blood pressure (BP) and cerebral function is well established. However, it is not clear whether a common mechanism could underlie the relationship between elevated BP and cognitive deficits. The expression of calcyon, a ge…
View article: Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis
Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis Open
As an important regulator of macrophage cholesterol efflux and HDL biogenesis, miR-33 is a promising target for treatment of atherosclerosis, and numerous studies demonstrate that inhibition of miR-33 increases HDL levels and reduces plaqu…
View article: Erratum
Erratum Open
View article: Modulation of meat quality by capsaicin in neuropathic White Pekin ducks
Modulation of meat quality by capsaicin in neuropathic White Pekin ducks Open
An experiment was conducted to study the effects of capsaicin on meat quality parameters and biochemical changes in a duck. There were 3 groups: control, neuropathic birds and treated group (sciatic nerve crush neuropathic pain) model alon…
View article: Endotoxin Disrupts Circadian Rhythms in Macrophages via Reactive Oxygen Species
Endotoxin Disrupts Circadian Rhythms in Macrophages via Reactive Oxygen Species Open
The circadian clock is a transcriptional network that functions to regulate the expression of genes important in the anticipation of changes in cellular and organ function. Recent studies have revealed that the recognition of pathogens and…
View article: Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II–Dependent Hypertension in Mice
Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II–Dependent Hypertension in Mice Open
Blood pressure exhibits a robust circadian rhythm in health. In hypertension, sleep apnea, and even shift work, this balanced rhythm is perturbed via elevations in night-time blood pressure, inflicting silent damage to the vasculature and …
View article: microRNAs in lipoprotein metabolism and cardiometabolic disorders
microRNAs in lipoprotein metabolism and cardiometabolic disorders Open
View article: Thanks to the Reviewers
Thanks to the Reviewers Open
View article: Contents Vol. 53, 2016
Contents Vol. 53, 2016 Open
View article: Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery
Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery Open
The circadian clock is rhythmically expressed in blood vessels, but the interaction between the circadian clock and disturbed blood flow remains unclear. We examined the relationships between BMAL1 and CLOCK and 2 regulators of endothelial…
View article: Conference Calendar
Conference Calendar Open