Daniel Paramythiotis
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View article: Management of peritoneal metastases from colorectal cancer and small bowel adenocarcinoma in patients with inflammatory bowel disease
Management of peritoneal metastases from colorectal cancer and small bowel adenocarcinoma in patients with inflammatory bowel disease Open
Patients with inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer, which may ultimately result in peritoneal metastases (PM). PM in patients with IBD is by nature difficult to treat due to the chronic in…
View article: Surgery Without Scalpel: Histotripsy as a Non-Invasive and Non-Thermal Modality for Liver Tumor Ablation
Surgery Without Scalpel: Histotripsy as a Non-Invasive and Non-Thermal Modality for Liver Tumor Ablation Open
Liver malignancies are among the most prevalent cancers worldwide and can be managed using various therapeutic approaches. However, the available options for treating these malignancies are characterized by several limitations. Histotripsy…
View article: Pancreatic Endometriosis Coexisting with a Splenic Mesothelial Cyst: A Rare Case Report and Review of the Literature
Pancreatic Endometriosis Coexisting with a Splenic Mesothelial Cyst: A Rare Case Report and Review of the Literature Open
Endometriosis is a clinical entity affecting up to 10% of women of reproductive age, characterized by ectopic endometrial tissue outside the uterine cavity. While extrapelvic endometriosis has been documented, pancreatic endometriosis rema…
View article: Synchronous Pancreatic Neoplasms Involving Pancreatic Ductal Adenocarcinoma: A Systematic Review of Case Reports
Synchronous Pancreatic Neoplasms Involving Pancreatic Ductal Adenocarcinoma: A Systematic Review of Case Reports Open
Background: Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy and is characterized by a very unfavorable prognosis. Rarely, patients may develop synchronous PDAC and another distinct primary pancreatic tumor,…
View article: Reassessing cholecystectomy timing in gallstone-related acute cholangitis
Reassessing cholecystectomy timing in gallstone-related acute cholangitis Open
In this article, we discussed the article by Sohail et al , published in a recent issue of the World Journal of Gastrointestinal Endoscopy . This study highlights the benefits of performing cholecystectomy (CCY) during the same hospitaliza…
View article: GATIS score: An innovative prognostic score for rectal neuroendocrine neoplasms
GATIS score: An innovative prognostic score for rectal neuroendocrine neoplasms Open
In this article, we discussed the article by Zeng et al , published in a recent issue of the World Journal of Gastroenterology . The publication represents a significant advancement in the prognostic evaluation of rectal neuroendocrine neo…
View article: Mesosigmoid Fossa Herniation: A Case of Jejunal Obstruction
Mesosigmoid Fossa Herniation: A Case of Jejunal Obstruction Open
BACKGROUND Internal hernias, a rare type of herniation, occur through deficits of peritoneum or mesentery/mesocolon. Herniation of the small intestine into the mesosigmoid fossa is an extraordinary situation. A possible diagnostic delay ma…
View article: The Effect of Hepatic Surgical Margins of Colorectal Liver Metastases on Prognosis: A Systematic Review and Meta-Analysis
The Effect of Hepatic Surgical Margins of Colorectal Liver Metastases on Prognosis: A Systematic Review and Meta-Analysis Open
Introduction: Colorectal cancer is the third most common malignancy, with around half of patients developing liver metastases. Hepatectomy is the preferred treatment, but its success depends on several factors, including surgical margins. …
View article: When to Intervene in Acute Necrotizing Pancreatitis: A Narrative Review of the Optimal Timing for Intervention Strategies
When to Intervene in Acute Necrotizing Pancreatitis: A Narrative Review of the Optimal Timing for Intervention Strategies Open
Introduction: Acute necrotizing pancreatitis (ANP) is the acute inflammation of pancreatic parenchyma, most commonly due to alcohol abuse or cholelithiasis. The treatment can be either conservative or invasive, including a variety of techn…
View article: Negative and Positive Predictors of Anastomotic Leakage in Colorectal Cancer Patients—The Case of Neutrophil-to-Lymphocyte Ratio
Negative and Positive Predictors of Anastomotic Leakage in Colorectal Cancer Patients—The Case of Neutrophil-to-Lymphocyte Ratio Open
Colorectal surgery for cancer is associated with a high rate of surgical complications, including anastomotic leakage. The ability to predict the risk of leakage early enough seems to be of high value, since it would facilitate the design …
View article: Focal Autoimmune Pancreatitis Morphologically Mimicking Pancreatic Cancer: A Case Report and Literature Review
Focal Autoimmune Pancreatitis Morphologically Mimicking Pancreatic Cancer: A Case Report and Literature Review Open
BACKGROUND Autoimmune pancreatitis (AIP) is identified as an outlier in the clinical practice of chronic pancreatitis caused by autoimmune system dysfunction. AIP is classified into 3 subtypes: AIP type 1 and AIP type 2, which are both sen…
View article: Comparative Assessment of Endoscopic Ultrasound-Guided Biopsies vs. Percutaneous Biopsies of Pancreatic Lesions: A Systematic Review and Meta-Analysis of Diagnostic Performance
Comparative Assessment of Endoscopic Ultrasound-Guided Biopsies vs. Percutaneous Biopsies of Pancreatic Lesions: A Systematic Review and Meta-Analysis of Diagnostic Performance Open
Introduction: Pancreatic cancer ranks as the fourth deadliest form of cancer. However, it is essential to note that not all pancreatic masses signal primary malignancy. Therefore, it is imperative to establish the correct differential diag…
View article: Incidental Finding of an Asymptomatic Jejunal Schwannoma: A Rare Case Report and Review of Literature
Incidental Finding of an Asymptomatic Jejunal Schwannoma: A Rare Case Report and Review of Literature Open
BACKGROUND Schwannomas are tumors that arise from Schwann cells that surround and support nerve cells. Most common sites for presentations are head, neck, and extremities. Schwannomas of gastrointestinal tract are rare, slow-growing tumors…
View article: Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review
Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review Open
Acute acalculous cholecystitis (AAC) represents cholecystitis without gallstones, occurring in approximately 5–10% of all cases of acute cholecystitis in adults. Several risk factors have been recognized, while infectious diseases can be a…
View article: Pancreatolithiasis: Does Management Depend on Clinical Manifestations?
Pancreatolithiasis: Does Management Depend on Clinical Manifestations? Open
BACKGROUND Pancreatic calculi (PC) or pancreatolithiasis refers to the presence of stones in the main pancreatic duct (MPD), side branches, or parenchyma of the pancreas. It is highly associated with chronic pancreatitis (CP), and is prese…
View article: What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research
What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research Open
Objectives-background: Postoperative cognitive dysfunction (POCD) involves decline in several cognitive domains after surgery and is particularly common after cardiac surgery, while also common among other types of surgery. Given the poten…
View article: Which Is the Best Way to Treat Massive Hemoptysis? A Systematic Review and Meta-Analysis of Observational Studies
Which Is the Best Way to Treat Massive Hemoptysis? A Systematic Review and Meta-Analysis of Observational Studies Open
Introduction: Hemoptysis is one of the most common symptoms of respiratory system diseases. Common causes include bronchiectasis, tumors, tuberculosis, aspergilloma, and cystic fibrosis. The severity of hemoptysis varies from mild to moder…
View article: Post-COVID-19 and Irritable Bowel Syndrome: A Literature Review
Post-COVID-19 and Irritable Bowel Syndrome: A Literature Review Open
The emergence of post-COVID-19 syndrome (PCS), a complex and multifactorial condition that follows the acute COVID-19 infection, has raised serious concerns within the global medical community. Concurrently, Irritable Bowel Syndrome (IBS),…
View article: A Rare Case of a Direct Incarcerated Inguinal Hernia Containing an Epiploic Appendage and a Literature Review.
A Rare Case of a Direct Incarcerated Inguinal Hernia Containing an Epiploic Appendage and a Literature Review. Open
Inguinal hernias are a widespread condition, responsible for a large number of acute abdomen cases. Typically, indirect, rather than direct, hernias lead to complications, as a consequence of their narrower hernial defect. We report a 71-y…
View article: The Prevalence of Gastrointestinal Bleeding in COVID-19 Patients: A Systematic Review and Meta-Analysis
The Prevalence of Gastrointestinal Bleeding in COVID-19 Patients: A Systematic Review and Meta-Analysis Open
Introduction: Severe acute respiratory syndrome coronavirus 2 caused the coronavirus disease of 2019 (COVID-19), which rapidly became a pandemic, claiming millions of lives. Apart from the main manifestations of this infection concerning t…
View article: Gastrointestinal Stromal Tumors: Our Ten-Year Experience of a Single-Center Tertiary Hospital
Gastrointestinal Stromal Tumors: Our Ten-Year Experience of a Single-Center Tertiary Hospital Open
Background: Gastrointestinal stromal tumors (GISTs) are the most frequent mesenchymal neoplasms of the gastrointestinal tract. They have variable clinical presentation, prognosis, and molecular characteristics. Here, we present the results…
View article: Bowel Perforation in Vascular Ehlers–Danlos Syndrome: Case Report and Comprehensive Review
Bowel Perforation in Vascular Ehlers–Danlos Syndrome: Case Report and Comprehensive Review Open
Introduction: Ehlers–Danlos syndromes (EDS) comprise a rare variety of genetic disorders, affecting all types of collagen. Herein, we describe a case of the vascular type of EDS, with coexisting segmental absence of intestinal musculature,…
View article: Updated Perspectives on the Diagnosis and Management of Familial Adenomatous Polyposis
Updated Perspectives on the Diagnosis and Management of Familial Adenomatous Polyposis Open
Familial adenomatous polyposis (FAP) is an autosomal dominant cancer predisposition syndrome marked by extensive colorectal polyposis and a high risk of colorectal cancer (CRC). Having access to screening and enrollment programs can improv…
View article: Bowel Perforation in Vascular EDS: A Case Report and a Comprehensive Review of the Literature
Bowel Perforation in Vascular EDS: A Case Report and a Comprehensive Review of the Literature Open
Introduction: Ehlers-Danlos syndromes (EDS) constitute a rare entity of genetic disorders, affecting the collagen of all types all. Herein, we describe a case of vascular type of EDS, with coexisting segmental absence of intestinal muscula…
View article: Uroperitoneum as a Complication of Laparoscopic Cholecystectomy: A Case Report
Uroperitoneum as a Complication of Laparoscopic Cholecystectomy: A Case Report Open
Background: Bladder rupture is more frequently encountered in blunt pelvic trauma, but can also be spontaneous or iatrogenic. Laparoscopic repair has been widely used during the last few years as a treatment for intraperitoneal bladder per…
View article: Drug-Induced Acute Pancreatitis in Hospitalized COVID-19 Patients
Drug-Induced Acute Pancreatitis in Hospitalized COVID-19 Patients Open
Coronavirus disease-19 (COVID-19), caused by SARS-CoV-2, is a systemic disease that affects not only the respiratory system, but also other systems, including gastrointestinal. A great number of different drugs have been used on hospitaliz…
View article: Surgical Management of Groove Pancreatitis: A Case Report
Surgical Management of Groove Pancreatitis: A Case Report Open
Groove pancreatitis (GP) is a chronic type of pancreatitis involving the groove area between the head of the pancreas, the duodenum, and the common bile duct. Alcohol abuse is one of the main pathogenetic factors, although its etiology is …
View article: Pancreatic Intraductal Papillary Mucinous Neoplasms: A Narrative Review
Pancreatic Intraductal Papillary Mucinous Neoplasms: A Narrative Review Open
Introduction: Intraductal papillary mucinous neoplasms (IPMNs) are the most frequent cystic pancreatic neoplasm. They derive from the main pancreatic duct or branch ducts. Aim: This narrative review aims to present and compare the current …
View article: Subcapsular Biloma following Endoscopic Retrograde Cholangiopancreatography and Endoscopic Biliary Sphincterotomy: A Case Report with a Mini Review of Literature
Subcapsular Biloma following Endoscopic Retrograde Cholangiopancreatography and Endoscopic Biliary Sphincterotomy: A Case Report with a Mini Review of Literature Open
A biloma is a loculated, extrahepatic, intra-abdominal bile collection. It is an unusual condition with an incidence of 0.3–2% and is usually a result of choledocholithiasis, iatrogenic injury or abdominal trauma causing disruption to the …
View article: Support Systems of Clinical Decisions in the Triage of the Emergency Department Using Artificial Intelligence: The Efficiency to Support Triage
Support Systems of Clinical Decisions in the Triage of the Emergency Department Using Artificial Intelligence: The Efficiency to Support Triage Open
Purpose: In the Emergency Departments (ED) the current triage systems that are been implemented are based completely on medical education and the perception of each health professional who is in charge. On the other hand, cutting-edge tech…