Paras Shah
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View article: Selective Tumor Cytotoxicity via Singlet Oxygen Generation: Investigating Eosinophil Peroxidase and Myeloperoxidase in Cancer Therapy
Selective Tumor Cytotoxicity via Singlet Oxygen Generation: Investigating Eosinophil Peroxidase and Myeloperoxidase in Cancer Therapy Open
Introduction: Eosinophil peroxidase (EPO) and myeloperoxidase (MPO) are large, cationic enzymes secreted by granulocytes that bind preferentially to negatively charged cancer cell membranes produced by the Warburg effect. In the presence o…
View article: Defining NECTIN4 Amplification and Protein Expression in Urothelial Carcinoma and Histologic Subtypes
Defining NECTIN4 Amplification and Protein Expression in Urothelial Carcinoma and Histologic Subtypes Open
View article: British Society for Haematology updated guidelines for the diagnosis and management of tumour lysis syndrome in adults and children with haematological malignancies: A focus on patient safety
British Society for Haematology updated guidelines for the diagnosis and management of tumour lysis syndrome in adults and children with haematological malignancies: A focus on patient safety Open
View article: Molecular Subtyping for Predicting Pathological Upstaging and Survival Outcomes in Clinically Organ-confined Bladder Cancer Patients Undergoing Radical Cystectomy
Molecular Subtyping for Predicting Pathological Upstaging and Survival Outcomes in Clinically Organ-confined Bladder Cancer Patients Undergoing Radical Cystectomy Open
View article: Knowledge, Attitude and Practice of Artificial Intelligence Among Healthcare Professionals at a Tertiary Care Teaching Hospital in South Gujarat
Knowledge, Attitude and Practice of Artificial Intelligence Among Healthcare Professionals at a Tertiary Care Teaching Hospital in South Gujarat Open
Background Artificial intelligence (AI) is rapidly evolving within healthcare, promising improvements in patient care, diagnostic accuracy, and therapeutic interventions. As AI technology becomes more integrated into clinical workflows, un…
View article: A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy
A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy Open
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup cor…
View article: Methylated DNA Markers in Voided Urine for the Identification of Clinically Significant Prostate Cancer
Methylated DNA Markers in Voided Urine for the Identification of Clinically Significant Prostate Cancer Open
Introduction: Non-invasive assays are needed to better discriminate patients with prostate cancer (PCa) to avoid over-treatment of indolent disease. We analyzed 14 methylated DNA markers (MDMs) from urine samples of patients with biopsy-pr…
View article: Knowledge, Attitude, and Practice of Materiovigilance Among Healthcare Professionals at a Tertiary Care Teaching Hospital
Knowledge, Attitude, and Practice of Materiovigilance Among Healthcare Professionals at a Tertiary Care Teaching Hospital Open
View article: Radiation therapy of renal cell carcinoma skeletal metastases – Does histologic subtype predict progression?
Radiation therapy of renal cell carcinoma skeletal metastases – Does histologic subtype predict progression? Open
Introduction: This investigation assessed whether the following factors were associated with radiographic local progression in bone metastases from renal cell carcinoma (RCC): (1) high-risk histologic features (2) lesional surgery (3) biol…
View article: Navigating Now and Next: Recent Advances and Future Horizons in Robotic Radical Prostatectomy
Navigating Now and Next: Recent Advances and Future Horizons in Robotic Radical Prostatectomy Open
Robotic-assisted radical prostatectomy (RARP) has become the leading approach for radical prostatectomy driven by innovations aimed at improving functional and oncological outcomes. The initial advancement in this field was transperitoneal…
View article: Relationship of Serum Magnesium, Serum Uric Acid Levels and Microalbuminuria in Patients with Type 2 Diabetes Mellitus
Relationship of Serum Magnesium, Serum Uric Acid Levels and Microalbuminuria in Patients with Type 2 Diabetes Mellitus Open
Background: Diabetic nephropathy is a serious side effect of diabetes mellitus. Microalbuminuria is a sign of diabetic nephropathy in people with type II mellitus. Studies have demonstrated that treatments to tightly regul…
View article: Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer
Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Open
Our results identify molecular signatures that can be used to differentiate MIBC NAC R versus NR, salient molecular pathway differences, and highlight the utility of molecular subtyping in relation to NAC response.
View article: Screening Vaccinees for Non-Communicable Diseases and Risk Factors at a Covid-19 Vaccination Center in Vadodara, Gujarat
Screening Vaccinees for Non-Communicable Diseases and Risk Factors at a Covid-19 Vaccination Center in Vadodara, Gujarat Open
Context: Adult population visiting COVID vaccination center is a potential teachable moment for screening and preventive advice on non-communicable diseases. Objectives: The objective of this study was to assess the proportion of vaccinees…
View article: Bim Expression in Peritumoral Lymphocytes is Associated with Survival in Patients with Metastatic Clear Cell Renal Cell Carcinoma
Bim Expression in Peritumoral Lymphocytes is Associated with Survival in Patients with Metastatic Clear Cell Renal Cell Carcinoma Open
BACKGROUND: Bim (BCL-2-interacting mediator of cell death) is a downstream pro-apoptotic signaling molecule activated by the PD-1 pathway. OBJECTIVE: We sought to determine if Bim expression in peritumoral T-lymphocytes (PTLs) is associate…
View article: Awareness of Occupational Therapy among Post-Graduate Resident Doctors and Speciality Medical Officers in Tertiary Healthcare Centre
Awareness of Occupational Therapy among Post-Graduate Resident Doctors and Speciality Medical Officers in Tertiary Healthcare Centre Open
Occupational Therapy (OT) is an essential speciality in healthcare system that aims to maximize people’sfunctional abilities and performance. Knowledge about OCCUPATIONAL THERAPY among healthcareprofessionals is essential for the delivery …
View article: Creation of Simulation-Based Curriculum of Perioperative Emergencies for Residents in Anesthesiology
Creation of Simulation-Based Curriculum of Perioperative Emergencies for Residents in Anesthesiology Open
View article: Prognostic Molecular Signatures for Metastatic Potential in Clinically Low-Risk Stage I and II Clear Cell Renal Cell Carcinomas
Prognostic Molecular Signatures for Metastatic Potential in Clinically Low-Risk Stage I and II Clear Cell Renal Cell Carcinomas Open
Introduction: For patients with localized node-negative (Stage I and II) clear cell renal cell carcinomas (ccRCC), current clinicopathological staging has limited predictive capability because of their low risk. Analyzing molecular …
View article: Genitourinary cancer management during a severe pandemic: Utility of rapid communication tools and evidence‐based guidelines
Genitourinary cancer management during a severe pandemic: Utility of rapid communication tools and evidence‐based guidelines Open
Objectives: To determine the usefulness of social media for rapid communication with experts to discuss strategies for prioritization and safety of deferred treatment for urologic malignancies during COVID‐19 pandemic, and to determine whe…
View article: Renal Cell Carcinoma with Inferior Vena Cava Extension: Can Classification Be Optimized to Predict Perioperative Outcomes?
Renal Cell Carcinoma with Inferior Vena Cava Extension: Can Classification Be Optimized to Predict Perioperative Outcomes? Open
Ambiguity exists regarding the definition of a level III inferior vena cava tumor thrombus (IVC-TT), limiting comparisons between open and minimally-invasive series. We assessed 253 patients who underwent radical nephrectomy with IVC-TT fr…
View article: Durable response of multiple myeloma and non‐small cell lung cancer with simultaneous, biologically targeted treatment
Durable response of multiple myeloma and non‐small cell lung cancer with simultaneous, biologically targeted treatment Open
Advances in therapy have improved outcomes for several incurable cancers. However, with improved survival the risk of developing second cancers becomes more clinically relevant and is further enhanced by some novel life-extending therapies…
View article: Reply by Authors
Reply by Authors Open
You have accessJournal of UrologyAdult Urology1 Feb 2020Reply by Authors Timothy D. Lyon, R. Houston Thompson, Paras H. Shah, Christine M. Lohse, Stephen A. Boorjian, Brian A. Costello, John C. Cheville, and Bradley C. Leibovich Timothy D.…
View article: MP09-17 WEIGHTED GLEASON GRADE GROUP (WGGG): A NEW PROSTATE CANCER BIOPSY REPORTING SYSTEM WITH PROGNOSTIC POTENTIAL
MP09-17 WEIGHTED GLEASON GRADE GROUP (WGGG): A NEW PROSTATE CANCER BIOPSY REPORTING SYSTEM WITH PROGNOSTIC POTENTIAL Open
You have accessJournal of UrologyProstate Cancer: Staging I (MP09)1 Apr 2019MP09-17 WEIGHTED GLEASON GRADE GROUP (WGGG): A NEW PROSTATE CANCER BIOPSY REPORTING SYSTEM WITH PROGNOSTIC POTENTIAL Zeynep Gul*, Nikhil Waingankar, Alberto Martin…
View article: MP42-13 ASSOCIATION OF PARTIAL VERSUS RADICAL NEPHRECTOMY WITH SUBSEQUENT HYPERTENSION RISK FOLLOWING RENAL TUMOR RESECTION
MP42-13 ASSOCIATION OF PARTIAL VERSUS RADICAL NEPHRECTOMY WITH SUBSEQUENT HYPERTENSION RISK FOLLOWING RENAL TUMOR RESECTION Open
You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy III (MP42)1 Apr 2019MP42-13 ASSOCIATION OF PARTIAL VERSUS RADICAL NEPHRECTOMY WITH SUBSEQUENT HYPERTENSION RISK FOLLOWING RENAL TUMOR RESECTION Paras Shah*, Bradle…
View article: MP25-06 COMPLETE METASTASECTOMY FOR RENAL CELL CARCINOMA IN THE CONTEMPORARY ERA
MP25-06 COMPLETE METASTASECTOMY FOR RENAL CELL CARCINOMA IN THE CONTEMPORARY ERA Open
You have accessJournal of UrologyKidney Cancer: Advanced (including Drug Therapy) II (MP25)1 Apr 2019MP25-06 COMPLETE METASTASECTOMY FOR RENAL CELL CARCINOMA IN THE CONTEMPORARY ERA Timothy Lyon*, R. Houston Thompson, Christine Lohse, Para…
View article: Implementation of multiparametric magnetic resonance imaging technology for evaluation of patients with suspicion for prostate cancer in the clinical practice setting
Implementation of multiparametric magnetic resonance imaging technology for evaluation of patients with suspicion for prostate cancer in the clinical practice setting Open
Objectives To investigate the impact of implementing magnetic resonance imaging (MRI) and ultrasonography fusion technology on biopsy and prostate cancer (PCa) detection rates in men presenting with clinical suspicion for PCa in the clinic…
View article: Prognostic evaluation of perinephric fat, renal sinus fat, and renal vein invasion for patients with pathological stage T3a clear‐cell renal cell carcinoma
Prognostic evaluation of perinephric fat, renal sinus fat, and renal vein invasion for patients with pathological stage T3a clear‐cell renal cell carcinoma Open
Objective To investigate the prognostic significance of various patterns of extrarenal extension that comprise pathological stage T3a clear‐cell renal cell carcinoma (ccRCC) amongst patients undergoing nephrectomy for non‐metastatic diseas…
View article: PD15-07 THE LIMITED ROLE OF CLINICAL VARIABLES AS PREDICTORS OF PATHOLOGIC DOWNSTAGING FROM NEOADJUVANT CHEMOTHERAPY: HIGHLIGHTING THE NEED FOR GENOMIC PREDICTORS
PD15-07 THE LIMITED ROLE OF CLINICAL VARIABLES AS PREDICTORS OF PATHOLOGIC DOWNSTAGING FROM NEOADJUVANT CHEMOTHERAPY: HIGHLIGHTING THE NEED FOR GENOMIC PREDICTORS Open
OS according to the derived risk groups and by comparing the observed and predicted OS in the VC.RESULTS: Multivariate analysis in the VC confirmed that age, Charlson-Deyo comorbidity score, cT stage, and facility type remained significant…
View article: PD16-12 PROGNOSTIC EVALUATION OF PERINEPHRIC FAT, RENAL SINUS FAT, AND RENAL VEIN INVASION FOR PATIENTS WITH PATHOLOGIC STAGE T3A RENAL CELL CARCINOMA
PD16-12 PROGNOSTIC EVALUATION OF PERINEPHRIC FAT, RENAL SINUS FAT, AND RENAL VEIN INVASION FOR PATIENTS WITH PATHOLOGIC STAGE T3A RENAL CELL CARCINOMA Open
You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy III1 Apr 2018PD16-12 PROGNOSTIC EVALUATION OF PERINEPHRIC FAT, RENAL SINUS FAT, AND RENAL VEIN INVASION FOR PATIENTS WITH PATHOLOGIC STAGE T3A RENAL CELL CARCINOMA…
View article: MP59-19 RADICAL NEPHRECTOMY FOR RECURRENT RENAL CELL CARCINOMA: PATIENT SELECTION FOR LAPAROSCOPIC APPROACH
MP59-19 RADICAL NEPHRECTOMY FOR RECURRENT RENAL CELL CARCINOMA: PATIENT SELECTION FOR LAPAROSCOPIC APPROACH Open
You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy VI1 Apr 2018MP59-19 RADICAL NEPHRECTOMY FOR RECURRENT RENAL CELL CARCINOMA: PATIENT SELECTION FOR LAPAROSCOPIC APPROACH Zachary Kozel, Amanda Myers, Paras Shah, El…
View article: Skin-to-tumor Distance Predicts Treatment Failure of T1A Renal Cell Carcinoma Following Percutaneous Cryoablation
Skin-to-tumor Distance Predicts Treatment Failure of T1A Renal Cell Carcinoma Following Percutaneous Cryoablation Open