Pascal Branchereau
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View article: Prospective Study of Recipient Human Leukocyte Antigen (HLA) Alloimmunization Following the Use of Cold-Stored Saphenous Vein Allografts in Vascular Surgery
Prospective Study of Recipient Human Leukocyte Antigen (HLA) Alloimmunization Following the Use of Cold-Stored Saphenous Vein Allografts in Vascular Surgery Open
Objectives: The aim of this study was to assess the HLA alloreactivity of cold-stored saphenous vein allografts (CSVAs) by identifying the production of HLA donor-specific antibodies (DSAs) in the recipient. The secondary objective was to …
View article: Spontaneous arteriovenous fistula of the splenic pedicle with isolated heart failure: A case report and litterature review
Spontaneous arteriovenous fistula of the splenic pedicle with isolated heart failure: A case report and litterature review Open
Arteriovenous fistulas (AVFs) of the splenic pedicle are rare entities. They are sometimes encountered at the stage of complications. The challenge is to treat patients at an early stage, to avoid complications, and possibly reverse it. He…
View article: Real-time multicompartment Hodgkin-Huxley neuron emulation on SoC FPGA
Real-time multicompartment Hodgkin-Huxley neuron emulation on SoC FPGA Open
Advanced computational models and simulations to unravel the complexities of brain function have known a growing interest in recent years in the field of neurosciences, driven by significant technological progress in computing platforms. M…
View article: Acute stress differently modulates interneurons excitability and synaptic plasticity in the primary motor cortex of wild‐type and SOD1<sup>G93A</sup> mouse model of ALS
Acute stress differently modulates interneurons excitability and synaptic plasticity in the primary motor cortex of wild‐type and SOD1<sup>G93A</sup> mouse model of ALS Open
Primary motor cortex (M1) network stability depends on activity of inhibitory interneurons, for which susceptibility to stress was previously demonstrated in limbic regions. Hyperexcitability in M1 following changes in the excitatory/inhib…
View article: Acute Type B Aortic Dissection: Insights From a Single-Center Retrospective Experience Over 12 Years
Acute Type B Aortic Dissection: Insights From a Single-Center Retrospective Experience Over 12 Years Open
Introduction: The treatment of acute type B aortic dissection (ATBAD) is currently a challenge for vascular surgeons, because of the early morbidity and mortality rates and the high risk of late aortic events up to 50% at 5 years. This stu…
View article: Excitatory action of low frequency depolarizing GABA/glycine synaptic inputs is prevalent in prenatal spinal SOD1<sup>G93A</sup> motoneurons
Excitatory action of low frequency depolarizing GABA/glycine synaptic inputs is prevalent in prenatal spinal SOD1<sup>G93A</sup> motoneurons Open
Amyotrophic lateral sclerosis (ALS) is a fatal adult‐onset neurodegenerative disease characterized by progressive motor neuron degeneration and muscle paralysis. Recent evidence suggests the dysfunction of inhibitory signalling in ALS moto…
View article: BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network
BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network Open
Characterization and modeling of biological neural networks is a field opening to major advances in our understanding of the mechanisms governing the functioning of the brain and the different pathologies that can affect it. Recent researc…
View article: BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network
BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network Open
Characterization and modeling of biological neural networks has emerged as a field driving significant advancements in our understanding of brain function and related pathologies. As of today, pharmacological treatments for neurological di…
View article: Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity
Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity Open
Renshaw cells (V1 R ) are excitable as soon as they reach their final location next to the spinal motoneurons and are functionally heterogeneous. Using multiple experimental approaches, in combination with biophysical modeling and dynamica…
View article: Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity
Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity Open
Renshaw cells (V1 R ) are excitable as soon as they reach their final location next to the spinal motoneurons and are functionally heterogeneous. Using multiple experimental approaches, in combination with biophysical modeling and dynamica…
View article: Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis
Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis Open
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive motor neuron degeneration and muscle paralysis. The early presymptomatic onset of abnormal processes is indicative of cumulative defects …
View article: Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks
Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks Open
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting motor neurons (MNs) during late adulthood. Here, with the aim of identifying early changes underpinning ALS neurodegeneration, we analyzed the GABAerg…
View article: Author response: Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks
Author response: Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks Open
Article Figures and data Abstract Introduction Results Discussion Materials and methods Appendix 1 Data availability References Decision letter Author response Article and author information Metrics Abstract Amyotrophic lateral sclerosis (…
View article: Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks
Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks Open
Spontaneous network activity (SNA) emerges in the spinal cord (SC) before the formation of peripheral sensory inputs and central descending inputs. SNA is characterized by recurrent giant depolarizing potentials (GDPs). Because GDPs in mot…