Pascal Duenk
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View article: Genetic analysis of keel bone fractures in laying hens housed in a quasi-commercial aviary
Genetic analysis of keel bone fractures in laying hens housed in a quasi-commercial aviary Open
Keel bone fractures (KBF) in laying hens are a major welfare problem in the egg production industry. While housing design and nutrition are known contributing factors, the role of genetics in KBF susceptibility is not well understood. The …
View article: 293. Using convolutional neural networks for image-based genomic prediction in mice
293. Using convolutional neural networks for image-based genomic prediction in mice Open
Convolutional neural networks (CNN) are well suited image recognition tools for their ability to recognize latent patterns from images. Here, we investigated whether CNN can be used for genomic prediction. We created genomic images from ge…
View article: 177. Predicting the purebred-crossbred genetic correlation from phenotype and genotype data of parental lines in pigs
177. Predicting the purebred-crossbred genetic correlation from phenotype and genotype data of parental lines in pigs Open
In previous work, we theoretically derived expressions for an upper and lower bound of the correlation between purebred and crossbred performance (r pc), using only variance components of the parental purebred lines. In the current study, …
View article: Review: optimizing genomic selection for crossbred performance by model improvement and data collection
Review: optimizing genomic selection for crossbred performance by model improvement and data collection Open
Breeding programs aiming to improve the performance of crossbreds may benefit from genomic prediction of crossbred (CB) performance for purebred (PB) selection candidates. In this review, we compared genomic prediction strategies that diff…
View article: Genetics of crossbreeding
Genetics of crossbreeding Open
In pig and poultry breeding programs, animals from genetically distinct purebred breeding lines are mated to produce crossbred animals, which provide food products to consumers. Although the aim of such breeding programs is to improve the …
View article: The Impact of Non-additive Effects on the Genetic Correlation Between Populations
The Impact of Non-additive Effects on the Genetic Correlation Between Populations Open
Average effects of alleles can show considerable differences between populations. The magnitude of these differences can be measured by the additive genetic correlation between populations (rg). This rg can be lower than one due to the pre…
View article: MOESM2 of Estimating the purebred-crossbred genetic correlation of body weight in broiler chickens with pedigree or genomic relationships
MOESM2 of Estimating the purebred-crossbred genetic correlation of body weight in broiler chickens with pedigree or genomic relationships Open
Additional file 2. Estimates of variance components for CB performance of BW35 from models that either fit a single G matrix (GEN_CB), or that separately fit a genetic sire component and a genetic dam component with two BOA matrices.
View article: MOESM1 of Estimating the purebred-crossbred genetic correlation of body weight in broiler chickens with pedigree or genomic relationships
MOESM1 of Estimating the purebred-crossbred genetic correlation of body weight in broiler chickens with pedigree or genomic relationships Open
Additional file 1. Estimates of variance components and purebred-crossbred genetic correlations of body weight around 7 (BW7) and 35Â days (BW35) for four models. Description: Estimates of variance components are presented for each purebre…
View article: Required properties for markers used to calculate unbiased estimates of the genetic correlation between populations
Required properties for markers used to calculate unbiased estimates of the genetic correlation between populations Open
For an unbiased estimation of the genetic correlation between populations, the markers should accurately predict the relationships at the causal loci. To achieve this, it is essential that the difference in allele frequencies between popul…
View article: Required marker properties for unbiased estimates of the genetic correlation between populations
Required marker properties for unbiased estimates of the genetic correlation between populations Open
Populations generally differ in environmental and genetic factors, which can create differences in allele substitution effects between populations. Therefore, a single genotype may have different additive genetic values in different popula…
View article: MOESM2 of Required properties for markers used to calculate unbiased estimates of the genetic correlation between populations
MOESM2 of Required properties for markers used to calculate unbiased estimates of the genetic correlation between populations Open
Additional file 2. Programs and seeds to simulate data. This file contains the input file used for QMSim, the Fortran-programs to select markers and causal loci for the different scenarios, the Fortran-program to simulate phenotypes and th…
View article: Benefits of Dominance over Additive Models for the Estimation of Average Effects in the Presence of Dominance
Benefits of Dominance over Additive Models for the Estimation of Average Effects in the Presence of Dominance Open
In quantitative genetics, the average effect at a single locus can be estimated by an additive (A) model, or an additive plus dominance (AD) model. In the presence of dominance, the AD-model is expected to be more accurate, because the A-m…