Pascal Frey
YOU?
Author Swipe
View article: Behind the shadow play: Shedding light on the population genetics of partially clonal organisms through clone age distributions
Behind the shadow play: Shedding light on the population genetics of partially clonal organisms through clone age distributions Open
Partial clonality is widespread in natural populations; however, the distributions of clone ages under different rates of clonality and their effects on genetic diversity remain unexplored. To fill this gap, we simulated partially clonal p…
View article: Uromyces plumbarius first reported on Oenothera lindheimeri in Europe with widespread distribution and association with two common natural enemies of rust fungi
Uromyces plumbarius first reported on Oenothera lindheimeri in Europe with widespread distribution and association with two common natural enemies of rust fungi Open
The rust fungus Uromyces plumbarius Peck was reported in Europe for the first time on Oenothera lindheimeri (Engelm. & A. Gray) W.L. Wagner & Hoch (Lindheimer's beeblossom), a highly popular ornamental plant widely cultivated since the 200…
View article: A mechanistic-statistical approach to infer dispersal and demography from invasion dynamics, applied to a plant pathogen
A mechanistic-statistical approach to infer dispersal and demography from invasion dynamics, applied to a plant pathogen Open
Dispersal, and in particular the frequency of long-distance dispersal (LDD) events, has strong implications for population dynamics with possibly the acceleration of the colonisation front, and for evolution with possibly the conservation …
View article: Poplar rust dispersal along the Durance River valley: inference of dispersal kernel and consequences
Poplar rust dispersal along the Durance River valley: inference of dispersal kernel and consequences Open
International audience
View article: A Global Assessment of the State of Plant Health
A Global Assessment of the State of Plant Health Open
The Global Plant Health Assessment (GPHA) is a collective, volunteer-based effort to assemble expert opinions on plant health and disease impacts on ecosystem services based on published scientific evidence. The GPHA considers a range of f…
View article: 48P An AI System for accurate Ki-67 IHC assessment in breast cancer following the IKWG whole section global scoring protocol
48P An AI System for accurate Ki-67 IHC assessment in breast cancer following the IKWG whole section global scoring protocol Open
Assessment of immunohistochemical (IHC) Ki-67 expression plays a crucial role in breast cancer diagnostics for many therapy decisions. The International Ki-67 in Breast Cancer Working Group (IKWG) has recently proposed a new global scoring…
View article: A mechanistic-statistical approach to infer dispersal and demography from invasion dynamics, applied to a plant pathogen
A mechanistic-statistical approach to infer dispersal and demography from invasion dynamics, applied to a plant pathogen Open
Dispersal, and in particular the frequency of long-distance dispersal (LDD) events, has strong implications for population dynamics with possibly the acceleration of the colonisation front, and for evolution with possibly the conservation …
View article: A survey of highly cited studies on plant pathogen effectors during the last two decades (2000-2020)
A survey of highly cited studies on plant pathogen effectors during the last two decades (2000-2020) Open
Plant effector biology is a research area that describes how plant-associated organisms modulate host structures and function to promote colonization by using small molecules (effectors). In this article, we analyzed 249 highly cited publi…
View article: Maths in Action in Contemporary Archaeology: numerical simulation of fire propagation in Roman buildings
Maths in Action in Contemporary Archaeology: numerical simulation of fire propagation in Roman buildings Open
This short paper explores the possibility of conducting high-performance computing simulations of complex fire propagation in buildings of archaeological interest. The simulation protocol described here involves several steps: (i) the geom…
View article: Tetrahedral remeshing in the context of large-scale numerical simulation and high performance computing
Tetrahedral remeshing in the context of large-scale numerical simulation and high performance computing Open
The purpose of this article is to discuss several modern aspects of remeshing, which is the task of modifying an ill-shaped tetrahedral mesh with bad size elements so that it features an appropriate density of high-quality elements. After …
View article: A Remarkable Expansion of Oligopeptide Transporter Genes in Rust Fungi (Pucciniales) Suggests a Specialization in Nutrient Acquisition for Obligate Biotrophy
A Remarkable Expansion of Oligopeptide Transporter Genes in Rust Fungi (Pucciniales) Suggests a Specialization in Nutrient Acquisition for Obligate Biotrophy Open
Nutrient acquisition by rust fungi during their biotrophic growth has been assigned to a few transporters expressed in haustorial infection structures. We performed a comparative genomic analysis of all transporter genes (hereafter termed …
View article: Improving sustainable crop protection using population genetics concepts
Improving sustainable crop protection using population genetics concepts Open
Growing genetically resistant plants allows pathogen populations to be controlled and reduces the use of pesticides. However, pathogens can quickly overcome such resistance. In this context, how can we achieve sustainable crop protection? …
View article: Improving sustainable crop protection using population genetics concepts
Improving sustainable crop protection using population genetics concepts Open
Growing genetically resistant plants allows pathogen populations to be controlled and reduces the use of chemicals. However, pathogens can quickly overcome such resistance. In this context, how can we achieve sustainable crop protection? T…
View article: A remarkable expansion of oligopeptide transporter genes in rust fungi (Pucciniales) suggests a specialization in nutrients acquisition for obligate biotrophy
A remarkable expansion of oligopeptide transporter genes in rust fungi (Pucciniales) suggests a specialization in nutrients acquisition for obligate biotrophy Open
Nutrients acquisition by rust fungi during their biotrophic growth has been assigned to a few transporters expressed in haustorial infection structures. We performed a comparative genomic analysis of all transporter genes (hereafter termed…
View article: <i>hp</i> -adaptive hybrid RANS/LES simulations for unstructured meshes with the discontinuous Galerkin method
<i>hp</i> -adaptive hybrid RANS/LES simulations for unstructured meshes with the discontinuous Galerkin method Open
In this paper, an hp-adaptation strategy designed for discontinuous Galerkin methods is applied to hybrid RANS/LES simulations. The 3D hp-adaptive strategy is suited for tetrahedral and hybrid prismatic/tetrahedral meshes, and relies on a …
View article: Genomic Signatures of a Major Adaptive Event in the Pathogenic Fungus <i>Melampsora larici-populina</i>
Genomic Signatures of a Major Adaptive Event in the Pathogenic Fungus <i>Melampsora larici-populina</i> Open
The recent availability of genome-wide sequencing techniques has allowed systematic screening for molecular signatures of adaptation, including in nonmodel organisms. Host–pathogen interactions constitute good models due to the strong sele…
View article: A point mutation and large deletion at the candidate avirulence locus <i>AvrMlp7</i> in the poplar rust fungus correlate with poplar RMlp7 resistance breakdown
A point mutation and large deletion at the candidate avirulence locus <i>AvrMlp7</i> in the poplar rust fungus correlate with poplar RMlp7 resistance breakdown Open
The deployment of plant varieties carrying resistance genes ( R ) exerts strong selection pressure on pathogen populations. Rapidly evolving avirulence genes ( Avr ) allow pathogens to escape R ‐mediated plant immunity through a variety of…
View article: A survey of highly influential studies on plant pathogen effectors during the last two decades (2000-2020)
A survey of highly influential studies on plant pathogen effectors during the last two decades (2000-2020) Open
International audience
View article: Expert annotation and life-cycle transcriptomics of transcription factors in rust fungi (Pucciniales) highlight the role of cold shock proteins in dormancy exit
Expert annotation and life-cycle transcriptomics of transcription factors in rust fungi (Pucciniales) highlight the role of cold shock proteins in dormancy exit Open
Fungi of the order Pucciniales are obligate plant biotrophs causing rust diseases. They exhibit a complex life cycle with the production of up to five spore types, infection of two unrelated hosts and an overwintering stage. Transcription …
View article: Association of two co-occurring mutations at the AvrMlp7 avirulence locus in poplar rust during the breakdown of RMlp7 resistance gene
Association of two co-occurring mutations at the AvrMlp7 avirulence locus in poplar rust during the breakdown of RMlp7 resistance gene Open
International audience
View article: Maths in Action in Contemporary Archaeology: numerical simulation of fire propagation in Roman buildings
Maths in Action in Contemporary Archaeology: numerical simulation of fire propagation in Roman buildings Open
This short paper explores the possibility of conducting high-performance computing simulations of complex fire propagation in buildings of archaeological interest. The simulation protocol described here involves several steps: i) the geome…
View article: Towards broad-spectrum resistance to Melampsora larici-populina rust in poplar: new genetic constructions and potential adaptation of the pathogen
Towards broad-spectrum resistance to Melampsora larici-populina rust in poplar: new genetic constructions and potential adaptation of the pathogen Open
Broad-spectrum resistance to Melampsora larici-populina (Mlp) leaf rust is a major challenge for poplar breeding in Northern Europe. When no rust epidemic was evident in the natural Populus nigra populations, cultivation of inter-specific …
View article: Breeding poplars with durable resistance to Melampsora larici-populina leaf rust : a multidisciplinary approach to understand and delay pathogen adaptation
Breeding poplars with durable resistance to Melampsora larici-populina leaf rust : a multidisciplinary approach to understand and delay pathogen adaptation Open
International audience