Pascal Hersen
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View article: “Morphogen gradients applied basally to human embryonic stem cells to control and dissect tissue patterning”
“Morphogen gradients applied basally to human embryonic stem cells to control and dissect tissue patterning” Open
Morphogen gradients are used repeatedly during development to pattern embryonic tissues. Absolute concentrations, duration or even temporal derivative of morphogen concentration have all been proposed to carry positional information. Howev…
View article: Amplitude-Modulated Singular Value Decomposition for Ultrafast Ultrasound Imaging of Gas Vesicles
Amplitude-Modulated Singular Value Decomposition for Ultrafast Ultrasound Imaging of Gas Vesicles Open
Ultrasound imaging holds significant promise for the observation of molecular and cellular phenomena through the utilization of acoustic contrast agents and acoustic reporter genes. Optimizing imaging methodologies for enhanced detection r…
View article: Optogenetic control of pheromone gradients and mating behavior in budding yeast
Optogenetic control of pheromone gradients and mating behavior in budding yeast Open
During mating in budding yeast, cells use pheromones to locate each other and fuse. This model system has shaped our current understanding of signal transduction and cell polarization in response to extracellular signals. The cell populati…
View article: Prediction of strain level phage–host interactions across the Escherichia genus using only genomic information
Prediction of strain level phage–host interactions across the Escherichia genus using only genomic information Open
View article: Nonlinear Singular Value Decomposition Beamforming for Ultrasound Imaging of Gas Vesicles
Nonlinear Singular Value Decomposition Beamforming for Ultrasound Imaging of Gas Vesicles Open
Ultrasound imaging holds significant promise for the observation of molecular and cellular phenomena through the utilization of acoustic contrast agents and acoustic reporter genes. Optimizing imaging methodologies for enhanced detection r…
View article: Author response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Author response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Full text Figures and data Peer review Side by side Abstract eLife assessment Introduction Results Discussion Materials and methods Data availability References Article and author information Abstract Natural environments of living organis…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Author Response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Author Response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Reviewer #2 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Reviewer #2 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Optogenetic control of pheromone gradients and mating behavior in budding yeast
Optogenetic control of pheromone gradients and mating behavior in budding yeast Open
During mating in budding yeast, cells use pheromones to locate each other and fuse. This model system has shaped our current understanding of signal transduction and cell polarization in response to extracellular signals. The cell-populati…
View article: Optogenetic spatial patterning of cooperation in yeast populations
Optogenetic spatial patterning of cooperation in yeast populations Open
View article: Predicting phage-bacteria interactions at the strain level from genomes
Predicting phage-bacteria interactions at the strain level from genomes Open
Predicting how phages can selectively infect specific bacterial strains holds promise for developing novel approaches to combat bacterial infections and better understanding microbial ecology. Experimental studies on phage-bacteria interac…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Optogenetic spatial patterning of cooperation in yeast populations
Optogenetic spatial patterning of cooperation in yeast populations Open
Microbial communities are a siege of complex metabolic interactions such as cooperation and competition for resources. Methods to control such interactions could lead to major advances in our ability to engineer microbial consortia for bio…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales
Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales Open
Optogenetics arises as a valuable tool to precisely control genetic circuits in microbial cell factories. Light control holds the promise of optimizing bioproduction methods and maximizing yields, but its implementation at different steps …
View article: A new look at an old classic: implementation of a SERS-based water hardness titration
A new look at an old classic: implementation of a SERS-based water hardness titration Open
The principle of complexometric titration is here revisited in SERS on the case of water hardness determination. The SERS signal abruptly switches about the equivalence, enabling quantitative SERS analysis without the need for tedious cali…
View article: Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales
Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales Open
Optogenetics arises as a valuable tool to precisely control genetic circuits in microbial cell factories. Light control holds the promise of optimizing bioproduction methods and maximize yields, but its implementation at different steps of…
View article: Lab513/Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales
Lab513/Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales Open
Dataset related to the article : S. Pouzet et al., Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales, 2022. See also the article on BioRXiv : https://www.biorxiv.org/content/10.1101/2022.10.31.514479v1 …
View article: Lab513/Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales
Lab513/Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales Open
Dataset related to the article : S. Pouzet et al., Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales, 2022. See also the article on BioRXiv : https://www.biorxiv.org/content/10.1101/2022.10.31.514479v1 …
View article: Datasets of titrations of mineral water hardness monitored using SERS
Datasets of titrations of mineral water hardness monitored using SERS Open
These datasets contains the spectral information used in a publication regarding the implementation of complexometric titrations of water hardness monitored using Surface Enhanced Raman Spectroscopy (SERS). The data consists of two csv fil…
View article: Datasets of titrations of mineral water hardness monitored using SERS
Datasets of titrations of mineral water hardness monitored using SERS Open
These datasets contains the spectral information used in a publication regarding the implementation of complexometric titrations of water hardness monitored using Surface Enhanced Raman Spectroscopy (SERS). The data consists of two csv fil…
View article: CyberSco.Py an open-source software for event-based, conditional microscopy
CyberSco.Py an open-source software for event-based, conditional microscopy Open
Timelapse fluorescence microscopy imaging is routinely used in quantitative cell biology. However, microscopes could become much more powerful investigation systems if they were endowed with simple unsupervised decision-making algorithms t…
View article: Decision letter: DetecDiv, a generalist deep-learning platform for automated cell division tracking and survival analysis
Decision letter: DetecDiv, a generalist deep-learning platform for automated cell division tracking and survival analysis Open
View article: CyberSco.Py: open-source software for event-based, conditional microscopy
CyberSco.Py: open-source software for event-based, conditional microscopy Open
Timelapse fluorescence microscopy imaging is routinely used in quantitative cell biology. However, microscopes could become much more powerful investigation systems if they were endowed with simple unsupervised decision-making algorithms t…
View article: Autonomous and Assisted Control for Synthetic Microbiology
Autonomous and Assisted Control for Synthetic Microbiology Open
The control of microbes and microbial consortia to achieve specific functions requires synthetic circuits that can reliably cope with internal and external perturbations. Circuits that naturally evolved to regulate biological functions are…