Pascal Kintz
YOU?
Author Swipe
View article: Case Report: A case study of positive doping control by animal-to-human drug transfer after an athlete administered medicine in spray format, containing clostebol acetate, to a pet dog
Case Report: A case study of positive doping control by animal-to-human drug transfer after an athlete administered medicine in spray format, containing clostebol acetate, to a pet dog Open
The presence of a doping substance in an athlete's biological sample may not be only related to intentional pharmacological support. The unintended use of a prohibited substance may be due various reasons. This paper describes the case of …
View article: Case report: Fatal long-term intoxication by 2,4-dinitrophenol and anabolic steroids in a young bodybuilder with muscle dysmorphia
Case report: Fatal long-term intoxication by 2,4-dinitrophenol and anabolic steroids in a young bodybuilder with muscle dysmorphia Open
A case of chronic intoxication by 2,4-dinitrophenol (2,4-DNP) is reported in a 21-year-old bodybuilder, also known as an abuser of anabolic steroids, who died after ingesting 2 grams of this substance after 6 months of repeated consumption…
View article: Interest of hair tests to discriminate a tail end of a doping regimen from a possible contamination in case of challenging an anti‐doping rule violation. V. Case reports involving trimetazidine, a drug where the concentration after a single 20 mg dose has been established
Interest of hair tests to discriminate a tail end of a doping regimen from a possible contamination in case of challenging an anti‐doping rule violation. V. Case reports involving trimetazidine, a drug where the concentration after a single 20 mg dose has been established Open
The identification of trimetazidine, a medicine used for treating stable angina pectoris and for preventing angina attacks, has been recently observed in doping cases involving high profile athletes from various countries over the world. I…
View article: Simultaneous detection of three hypoxia‐inducible factor stabilizers—molidustat, roxadustat, and vadadustat—in multiple keratinized matrices and its application in a doping context
Simultaneous detection of three hypoxia‐inducible factor stabilizers—molidustat, roxadustat, and vadadustat—in multiple keratinized matrices and its application in a doping context Open
In a doping case, a top athlete challenged an anti‐doping rule violation, involving molidustat. Molidustat is a stabilizing agent of the hypoxia‐inducible factor (HIF) recently developed. It is currently undergoing clinical trials for anem…
View article: Is it really possible to kill with insulin without leaving traces? From lifesaver to killer, the issues surrounding the analytical characterization of postmortem insulin illustrated by an exemplary case
Is it really possible to kill with insulin without leaving traces? From lifesaver to killer, the issues surrounding the analytical characterization of postmortem insulin illustrated by an exemplary case Open
Evidence of an insulin overdose is very complicated in the medico‐legal field. The analysis and subsequent interpretation of results is complex, especially when treating postmortem blood samples. The instability of insulin, the special pre…
View article: Perspectives and Challenges of Hair Analysis
Perspectives and Challenges of Hair Analysis Open
Hair analysis is a reliable and widely used tool to evaluate drug exposure in many fields, including workplace testing, drug abuse history and withdrawal control, post-mortem toxicology, doping control, therapeutic drug monitoring of pharm…
View article: Trends in Fatal Poisoning Among Drug Users in France From 2011 to 2021
Trends in Fatal Poisoning Among Drug Users in France From 2011 to 2021 Open
Importance The DRAMES (Décès en Relation avec l’Abus de Médicaments Et de Substances) register is a database of drug-related deaths with the aim of identifying the psychoactive substances associated with and estimating the trends in these …
View article: Testing for clomiphene in keratinous matrices (hair and nail)
Testing for clomiphene in keratinous matrices (hair and nail) Open
Clomiphene or clomifene is a selective estrogen receptor modulator used to treat female fertility in case of ovulatory dysfunction. In sport, clomiphene is prohibited at all times for use by athletes and is listed in the section S4.2 (horm…
View article: Intentional overdose of glargine insulin: Determination of the parent compound in postmortem blood by <scp>LC‐HRMS</scp>
Intentional overdose of glargine insulin: Determination of the parent compound in postmortem blood by <span>LC‐HRMS</span> Open
Insulin glargine is a long‐acting insulin analog that is converted after enzymatic cleavage of the arginine pair of the β‐chain into its main metabolite M1 (21 A ‐Gly‐insulin), which is responsible for the hypoglycemic activity. In all the…
View article: Fingerprints: A New Specimen for Innovative Applications for the Detection of Xenobiotics
Fingerprints: A New Specimen for Innovative Applications for the Detection of Xenobiotics Open
Fingerprints are invisible traces that result from a deposition of sweat and sebum present on the papillary ridges. As sweat and sebum contain drugs, fingerprints are promising since collection is rapid, non-invasive and difficult to falsi…
View article: Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- δ) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516 (Cardarine) and MK2866 (Ostarine)
Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- δ) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516 (Cardarine) and MK2866 (Ostarine) Open
A 43-year-old male, sport coach, presented him-self at the Emergency unit of a local hospital for epigastric pain, myalgia pain and severe headache. He claimed having used for some days a combination of GW1516 (cardarine), a peroxisome pro…
View article: Forensic investigations in a case of aggressive behavior of three dogs: Identification of dietary supplements contamination by metandienone and confirmation by hair tests
Forensic investigations in a case of aggressive behavior of three dogs: Identification of dietary supplements contamination by metandienone and confirmation by hair tests Open
After observing a modification in behavior of his three dogs, an owner consulted a laboratory to determine if a drug could be involved. Hair strands of each animal were collected from the neck area and sent to the laboratory for anabolic s…
View article: Determination of 3-MeO-PCP in human blood and urine in a fatal intoxication case, with a specific focus on metabolites identification
Determination of 3-MeO-PCP in human blood and urine in a fatal intoxication case, with a specific focus on metabolites identification Open
3-Methoxyphencyclidine (3-MeO-PCP) is a new psychoactive substance that belongs to the phencyclidines family, first identified in Europe in 2012. This drug presents a stronger binding to N-methyl-D-aspartate (NMDA) receptors when compared …
View article: Issue Information
Issue Information Open
A novel chitosan/tripolyphosphate
View article: Cocaine External Contamination Can Be Documented by a Hair Test
Cocaine External Contamination Can Be Documented by a Hair Test Open
In 1979, the publication of the pioneer paper of the American scientist Annette Baumgartner and colleagues (1) dramatically changed the window of drug detection.Using radio-immunological tests, the authors demonstrated that repetitive expo…