Pascal Lutumba
YOU?
Author Swipe
View article: Impact of praziquantel treatment and early reinfection patterns in a mixed Schistosoma mansoni and Schistosoma haematobium infection focus in the Democratic Republic of Congo
Impact of praziquantel treatment and early reinfection patterns in a mixed Schistosoma mansoni and Schistosoma haematobium infection focus in the Democratic Republic of Congo Open
Objective To evaluate the impact of single versus mixed Schistosoma infections on the efficacy of PZQ treatment as well as on the dynamics of reinfection after treatment. Methods We followed 388 randomly selected residents of a village co-…
View article: <i>Coxiella burnetii</i> and <i>Bartonella</i> species serology of febrile patients with an established infectious or inflammatory diagnosis in Sudan, Nepal, and Cambodia
<i>Coxiella burnetii</i> and <i>Bartonella</i> species serology of febrile patients with an established infectious or inflammatory diagnosis in Sudan, Nepal, and Cambodia Open
Coxiella burnetii and Bartonella species cause febrile illness and infective endocarditis in low- and middle-income countries (LMICs). This study investigated whether seropositivity to C. burnetii or Bartonella could be detected among pati…
View article: Correlates of viral load suppression among people living with HIV on antiretroviral treatment in Mbujimayi, Democratic Republic of Congo
Correlates of viral load suppression among people living with HIV on antiretroviral treatment in Mbujimayi, Democratic Republic of Congo Open
Context This study was conducted in Mbujimayi to assess viral load suppression in people living with HIV (PLWH) on antiretroviral therapy (ART). The main objective was to identify the key factors influencing the success of viral suppressio…
View article: Perceptions, Challenges and Barriers to HIV Care in Mbujimayi in the East Kasai Province, DR Congo: A Qualitative Study
Perceptions, Challenges and Barriers to HIV Care in Mbujimayi in the East Kasai Province, DR Congo: A Qualitative Study Open
This study highlights the many challenges that need to be overcome to improve HIV/AIDS care, particularly in terms of accessing care and combating stigma. To improve the effectiveness of health programs, an integrated multisectoral approac…
View article: Factors Associated with ART Adherence and Viral Load Suppression Among Persons Living with HIV in Likasi, Democratic Republic of Congo
Factors Associated with ART Adherence and Viral Load Suppression Among Persons Living with HIV in Likasi, Democratic Republic of Congo Open
The 90-90-90 UNAIDS targets to measure the progress toward HIV control were not achieved globally in 2020, with significant differences between countries. Many low- and middle-income countries in sub-Saharan Africa, including the DRC, had …
View article: Maxillofacial cemento-ossifying fibroma: A rare case report
Maxillofacial cemento-ossifying fibroma: A rare case report Open
View article: Effectiveness of Pyrethroid-Piperonyl Butoxide Nets Versus Standard Pyrethroid-Only Nets in Preventing Malaria in Children Under 10 Years Living in Kisantu Health Zone, Democratic Republic of the Congo
Effectiveness of Pyrethroid-Piperonyl Butoxide Nets Versus Standard Pyrethroid-Only Nets in Preventing Malaria in Children Under 10 Years Living in Kisantu Health Zone, Democratic Republic of the Congo Open
Democratic Republic of the Congo (DRC) is among the countries that have a high malaria incidence. In an effort to combat this public health challenge, innovative tools and strategies are being developed and evaluated. Among the new generat…
View article: Knowledge, Attitudes, and Perceptions of Healthcare Providers Regarding Sickle Cell Disease and Its Newborn Screening in Mbuji-Mayi, DRC
Knowledge, Attitudes, and Perceptions of Healthcare Providers Regarding Sickle Cell Disease and Its Newborn Screening in Mbuji-Mayi, DRC Open
Background: Sickle Cell Disease (SCD) remains a major public health issue in sub-Saharan Africa. Newborn screening (NBS) programs are crucial for early diagnosis and improved survival. However, their effectiveness depends largely on health…
View article: Evidence of Coxiella burnetii and Bartonella species infections among patients with persistent febrile illness in four low- and middle-income countries
Evidence of Coxiella burnetii and Bartonella species infections among patients with persistent febrile illness in four low- and middle-income countries Open
View article: Intermittent screening using ultra-sensitive malaria rapid diagnostic test and treatment with pyronaridine-artesunate compared to standard preventive treatment with sulfadoxine-pyrimethamine for malaria prevention in pregnant women in Kinshasa, DRC
Intermittent screening using ultra-sensitive malaria rapid diagnostic test and treatment with pyronaridine-artesunate compared to standard preventive treatment with sulfadoxine-pyrimethamine for malaria prevention in pregnant women in Kinshasa, DRC Open
NCT04783051.
View article: Evidence on the Impact of Community Health Workers on Health Indicators in Congo: A Quasi-Experimental Temporal Study
Evidence on the Impact of Community Health Workers on Health Indicators in Congo: A Quasi-Experimental Temporal Study Open
View article: PA-69 Performance of ultra-sensitive malaria rapid diagnostic test to detect plasmodium falciparum infection in pregnant women in Kinshasa, the Democratic Republic of the Congo
PA-69 Performance of ultra-sensitive malaria rapid diagnostic test to detect plasmodium falciparum infection in pregnant women in Kinshasa, the Democratic Republic of the Congo Open
Background Low peripheral parasitemia caused by sequestration of Plasmodium falciparum in the placenta hampers the diagnosis of malaria in pregnant women, leading to microscopy or conventional rapid diagnostic tests (co-RDTs) false-negativ…
View article: Performance of ultra-sensitive malaria rapid diagnostic test to detect Plasmodium falciparum infection in pregnant women in Kinshasa, the Democratic Republic of the Congo
Performance of ultra-sensitive malaria rapid diagnostic test to detect Plasmodium falciparum infection in pregnant women in Kinshasa, the Democratic Republic of the Congo Open
Background Low peripheral parasitaemia caused by sequestration of Plasmodium falciparum in the placenta hampers the diagnosis of malaria in pregnant women, leading to microscopy or conventional rapid diagnostic tests (RDTs) false-negative …
View article: Schistosoma Infection Burden and Risk Factors among School-Aged Children in a Rural Area of the Democratic Republic of the Congo
Schistosoma Infection Burden and Risk Factors among School-Aged Children in a Rural Area of the Democratic Republic of the Congo Open
Despite continuous efforts to control schistosomiasis (SCH) in the Democratic Republic of the Congo (DRC), it still poses a significant challenge. In order to enhance control measures, additional research is necessary. This study documents…
View article: Exploring The Experiments of Mass Distributions of Bed Nets in The Community to Prevent Malaria in Kisantu Health Zone, Democratic Republic of Congo: A Qualitative Study
Exploring The Experiments of Mass Distributions of Bed Nets in The Community to Prevent Malaria in Kisantu Health Zone, Democratic Republic of Congo: A Qualitative Study Open
Despite its discovery more than a century, malaria remains a of public health problem. One of the pillars in the strategy to fighting it is the use of the mosquito net, which remains the only significant tool of prevention. This study is t…
View article: Phylogeographic analysis of dengue virus serotype 1 and cosmopolitan serotype 2 in Africa
Phylogeographic analysis of dengue virus serotype 1 and cosmopolitan serotype 2 in Africa Open
Active genomic surveillance of DENV in Africa at the portals of entry might help early outbreak response and limit sero- and genotype spread and human disease burden.
View article: Prevalence and predictors of adverse events following exposure to long-lasting insecticidal nets used for malaria prevention: a community based cross-sectional study in the Democratic Republic of the Congo
Prevalence and predictors of adverse events following exposure to long-lasting insecticidal nets used for malaria prevention: a community based cross-sectional study in the Democratic Republic of the Congo Open
Background Malaria morbidity and mortality increase in the Democratic Republic of the Congo (DRC) may be the consequence of the low utilization rate of long-lasting insecticidal nets (LLINs) resulting from poor compliance due to adverse ev…
View article: Malaria among children under 10 years in 4 endemic health areas in Kisantu Health Zone: epidemiology and transmission
Malaria among children under 10 years in 4 endemic health areas in Kisantu Health Zone: epidemiology and transmission Open
Background The Democratic Republic of the Congo (DRC) is the second most malaria-affected country in the world with 21,608,681 cases reported in 2019. The Kongo Central (KC) Province has a malaria annual incidence of 163 cases/per 1000 inh…
View article: Comparison of intermittent screening (using ultra-sensitive malaria rapid diagnostic test) and treatment (using a newly registered antimalarial pyronaridine-artesunate—PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas: ULTRAPYRAPREG
Comparison of intermittent screening (using ultra-sensitive malaria rapid diagnostic test) and treatment (using a newly registered antimalarial pyronaridine-artesunate—PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas: ULTRAPYRAPREG Open
Background Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is an important malaria control strategy in sub-Saharan Africa. Indeed, it overcomes the risk of misdiagnosis due to low peripheral parasi…
View article: Diagnosis of Schistosomiasis without a Microscope: Evaluating Circulating Antigen (CCA, CAA) and DNA Detection Methods on Banked Samples of a Community-Based Survey from DR Congo
Diagnosis of Schistosomiasis without a Microscope: Evaluating Circulating Antigen (CCA, CAA) and DNA Detection Methods on Banked Samples of a Community-Based Survey from DR Congo Open
Detection of Schistosoma eggs in stool or urine is known for its low sensitivity in diagnosing light infections. Alternative diagnostics with better sensitivity while remaining highly specific, such as real-time PCR and circulating antigen…
View article: Comparison of intermittent screening (using ultra-sensitive malaria Rapid Diagnostic test) and treatment (using a newly registered antimalarial Pyronaridine - Artesunate – PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas. ULTRAPYRAPREG
Comparison of intermittent screening (using ultra-sensitive malaria Rapid Diagnostic test) and treatment (using a newly registered antimalarial Pyronaridine - Artesunate – PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas. ULTRAPYRAPREG Open
Background Intermittent Preventive Treatment in pregnancy (IPTp) with Sulfadoxine-Pyrimethamine (SP) is an important malaria control strategy in sub-Saharan Africa. Indeed it overcomes the risk of misdiagnosis due to low peripheral parasit…
View article: Etiological spectrum of persistent fever in the tropics and predictors of ubiquitous infections: a prospective four-country study with pooled analysis
Etiological spectrum of persistent fever in the tropics and predictors of ubiquitous infections: a prospective four-country study with pooled analysis Open
View article: Malaria among children under 10 years in 4 endemic health areas in Kisantu Health Zone: epidemiology and transmission
Malaria among children under 10 years in 4 endemic health areas in Kisantu Health Zone: epidemiology and transmission Open
Introduction The Democratic Republic of Congo (DRC) is the second most malaria-affected country globally with 21,608,681 cases reported in 2019. The Kongo Central (KC) Province has a malaria annual incidence of 163 cases/per 1000 inhabitan…
View article: Impact of Anthelmintic Treatment on the Burden of Helminth Infections in Primary Schoolchildren in Biyela Health Zone in Kinshasa, Democratic Republic of the Congo
Impact of Anthelmintic Treatment on the Burden of Helminth Infections in Primary Schoolchildren in Biyela Health Zone in Kinshasa, Democratic Republic of the Congo Open
Background: The study evaluated the impact of anthilminthic treatment, given as non-investigational drugs, on helminth infections, anaemia, and hemoglobin (Hb) level in the context of a malaria clinical trial in which Sulfadoxine Pyrimetha…
View article: High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo
High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo Open
Background The epidemiology of human cysticercosis and neurocysticercosis, caused by the larval stage of the pork tapeworm Taenia solium , is not well known in the Democratic Republic of Congo (DRC). Within a multicenter etiological and di…
View article: Onchocerciasis Prevalence among Persons with Epilepsy in an Onchocerciasis Hypo-Endemic Area in the Democratic Republic of Congo: A Cross-Sectional Study
Onchocerciasis Prevalence among Persons with Epilepsy in an Onchocerciasis Hypo-Endemic Area in the Democratic Republic of Congo: A Cross-Sectional Study Open
A high epilepsy prevalence has been reported in onchocerciasis meso- and hyper-endemic regions in sub-Saharan Africa, including in the Democratic Republic of Congo (DRC). We investigated whether onchocerciasis-associated epilepsy can also …
View article: Performance of Malaria Rapid Diagnostic Test in Asymptomatic Malaria Cases in Stable Transmission Area in Kisantu, Democratic Republic of Congo
Performance of Malaria Rapid Diagnostic Test in Asymptomatic Malaria Cases in Stable Transmission Area in Kisantu, Democratic Republic of Congo Open
Background: Democratic Republic of Congo has shifted from pan test to mono-specific malaria RDT tests. A new Histidine rich protein 2 (HRP2)-based Rapid Diagnostic Tests for malaria diagnosis was then implemented. Objective: …
View article: Preventive malaria treatment among school-aged children in sub-Saharan Africa: a systematic review and meta-analyses
Preventive malaria treatment among school-aged children in sub-Saharan Africa: a systematic review and meta-analyses Open
View article: Development and implementation of a strategy for intensified screening for gambiense human African trypanosomiasis in Kongo Central province, DRC
Development and implementation of a strategy for intensified screening for gambiense human African trypanosomiasis in Kongo Central province, DRC Open
This programme has demonstrated that it is possible to deploy passive screening for HAT at sub-country or country levels in the DRC, and this is made more effective when supplemented with reactive screening. Results and achievements showed…
View article: High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo.
High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo. Open
Background The epidemiology of human cysticercosis and neurocysticercosis, caused by the larval stage of the pork tapeworm Taenia solium , is not well known in the Democratic Republic of Congo (DRC). As part of an etiological study, we con…