Pasindu Hansana Singhaarachchi
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View article: Rodent models of Alzheimer's disease: Critical analysis of current hypotheses and pathways for future research
Rodent models of Alzheimer's disease: Critical analysis of current hypotheses and pathways for future research Open
Alzheimer's disease (AD) was first described over a century ago. However, the mechanisms underlying the disease are not well understood to this day. This has negatively impacted our ability to create animal models to design and test target…
View article: The role of n-3-derived specialised pro-resolving mediators (SPMs) in microglial mitochondrial respiration and inflammation resolution in Alzheimer’s disease
The role of n-3-derived specialised pro-resolving mediators (SPMs) in microglial mitochondrial respiration and inflammation resolution in Alzheimer’s disease Open
Alzheimer’s disease (AD) is the most common form of dementia globally and is characterised by reduced mitochondrial respiration and cortical deposition of amyloid-β plaques and neurofibrillary tangles comprised of hyper-phosphorylated tau.…
View article: Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer’s disease research
Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer’s disease research Open