Patricia D. A. Rohs
YOU?
Author Swipe
View article: A role for the Gram-negative outer membrane in bacterial shape determination
A role for the Gram-negative outer membrane in bacterial shape determination Open
The cell envelope of Gram-negative bacteria consists of three distinct layers: the cytoplasmic membrane, a cell wall made of peptidoglycan (PG), and an asymmetric outer membrane (OM) composed of phospholipid in the inner leaflet and lipopo…
View article: A role for the Gram-negative outer membrane in bacterial shape determination
A role for the Gram-negative outer membrane in bacterial shape determination Open
The cell envelope of Gram-negative bacteria consists of three distinct layers: the cytoplasmic membrane, a cell wall made of peptidoglycan (PG), and an asymmetric outer membrane (OM) composed of phospholipid in the inner leaflet and lipopo…
View article: Growth and Division of the Peptidoglycan Matrix
Growth and Division of the Peptidoglycan Matrix Open
Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and protects them from osmotic lysis. The expansion and division of this structure therefore plays an integral role in bacterial growth and division. Additi…
View article: Identification of Potential Regulatory Domains within the MreC and MreD Components of the Cell Elongation Machinery
Identification of Potential Regulatory Domains within the MreC and MreD Components of the Cell Elongation Machinery Open
Cell shape in bacteria is largely determined by the cell wall structure that surrounds them. The multiprotein machine called the Rod system (elongasome) has long been implicated in rod shape determination in bacilli.
View article: MltG activity antagonizes cell wall synthesis by both types of peptidoglycan polymerases in <i>Escherichia coli</i>
MltG activity antagonizes cell wall synthesis by both types of peptidoglycan polymerases in <i>Escherichia coli</i> Open
Bacterial cells are surrounded by a peptidoglycan (PG) cell wall. This structure is essential for cell integrity and its biogenesis pathway is a key antibiotic target. Most bacteria utilize two types of synthases that polymerize glycan str…
View article: A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery
A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery Open
Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved morphogenic complex that spatially controls cell wall assembly by the glycan polymerase RodA and crosslinking enzyme PBP2. Using Escherichia coli as a model …
View article: An activation pathway governs cell wall polymerization by a bacterial morphogenic machine
An activation pathway governs cell wall polymerization by a bacterial morphogenic machine Open
Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved morphogenic complex that spatially controls cell wall (CW) assembly. In Escherichia coli , alterations in a CW synthase component of the system called PBP2 w…