Patricio Pichling
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View article: HNRNPH1-mediated splicing events regulate EIF4G1 transcript variant composition and the organization of the AURKA 5' UTR
HNRNPH1-mediated splicing events regulate EIF4G1 transcript variant composition and the organization of the AURKA 5' UTR Open
HNRNPH1 is a regulator of alternative splicing, but few studies have defined the splicing events it mediates. Here, we used short- and long-read RNA sequencing to interrogate the transcriptome-wide effects of HNRNPH1 depletion and its regu…
View article: EWSR1’s visual modalities are defined by its association with nucleic acids and RNA polymerase II
EWSR1’s visual modalities are defined by its association with nucleic acids and RNA polymerase II Open
We report systematic analysis of endogenous EWSR1’s cellular organization. We demonstrate that EWSR1, which contains low complexity and nucleic acid binding domains, is present in cells in faster and slower-recovering fractions, indicative…