Patrick Adu
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View article: Knowledge, Attitudes, Practices, and Misconceptions Regarding Vitamins in Blood Metabolism and Anemia Among University Students: A One Center Cross‐Sectional Study in Ghana
Knowledge, Attitudes, Practices, and Misconceptions Regarding Vitamins in Blood Metabolism and Anemia Among University Students: A One Center Cross‐Sectional Study in Ghana Open
Background In Sub‐Saharan Africa, anemia is a significant public health issue, affecting individuals of all ages. While prevention efforts focus on infants, children, and pregnant women, adolescents are overlooked often, leading to ongoing…
View article: Mixed-methods exploration of knowledge about causes and prevention of anaemia in reproductive-aged women; a two-centre study
Mixed-methods exploration of knowledge about causes and prevention of anaemia in reproductive-aged women; a two-centre study Open
Anaemia data disaggregation is important in contextualizing its public health relevance. Systems thinking approaches, such as health sector-community working groups adopting culturally-sensitive educational intervention strategies, are nee…
View article: Lack of standardization of blood donor recruitment processes: A two-center mixed-methods audit study in Ghana
Lack of standardization of blood donor recruitment processes: A two-center mixed-methods audit study in Ghana Open
Objective: Sub-Saharan African countries perennially suffer acute donor blood shortfalls. Clinical audit is a quality improvement strategy that enables the identification of actionable points to improve healthcare delivery. This study audi…
View article: Clustered regularly interspaced short palindromic repeats (CRISPR)-Diagnostics for differential detection of haemoglobin variant S, C, D and E
Clustered regularly interspaced short palindromic repeats (CRISPR)-Diagnostics for differential detection of haemoglobin variant S, C, D and E Open
Although haemoglobin variants are prevalent in low- and middle-income countries, the exact disease burden remains unknown due to a lack of diagnostic capacity. Traditionally, routine clinical haemoglobin variant diagnostics have relied on …
View article: Exploring the sickle cell disease knowledge of premarital counseling team members of faith groups; a multi-center mixed-methods study
Exploring the sickle cell disease knowledge of premarital counseling team members of faith groups; a multi-center mixed-methods study Open
Background Sickle cell disease (SCD) is a prevalent monogenic disorder of haemoglobin in sub-Saharan Africa. Being recessively inherited, SCD is preventable through public health educational strategies targeting would-be couples. As faith …
View article: Anaemia status is associated with insufficient iodine levels in pregnant women in rural settings; a two-centre observational study
Anaemia status is associated with insufficient iodine levels in pregnant women in rural settings; a two-centre observational study Open
Background: Adequate maternal hemoglobin and iodine are essential for optimal fetal-placental oxygenation, and, fetal brain development respectively. Intra-pregnancy anemia and iodine insufficiency are associated with adverse fetal-materna…
View article: Exploring Adverse Blood Donation Reactions Among Whole Blood Donors at a Tertiary Hospital Setting: A One‐Center Observational Mixed‐Methods Study
Exploring Adverse Blood Donation Reactions Among Whole Blood Donors at a Tertiary Hospital Setting: A One‐Center Observational Mixed‐Methods Study Open
Background Although blood donation saves lives, it may be associated with adverse reactions. These reactions may be immediate or delayed and may be a factor in donor nonreturn. However, there is limited knowledge about blood donation–relat…
View article: Assessment of the Knowledge of Chronic Kidney Disease and Anemia Among University Students in Ghana: A Cross‐Sectional Study
Assessment of the Knowledge of Chronic Kidney Disease and Anemia Among University Students in Ghana: A Cross‐Sectional Study Open
Background: Chronic kidney disease (CKD) is typically associated with anemia, with both implicated in global mortalities and morbidities. Adequate knowledge about these conditions might help individuals to prevent and/or manage them effect…
View article: Diagnostic value of neutrophil gelatinase-associated lipocalin and neutrophil-to-lymphocyte ratio in type 2 diabetes mellitus individuals with reduced estimated glomerular filtration rate(eGFR): A case-control study in a municipal hospital in Ghana
Diagnostic value of neutrophil gelatinase-associated lipocalin and neutrophil-to-lymphocyte ratio in type 2 diabetes mellitus individuals with reduced estimated glomerular filtration rate(eGFR): A case-control study in a municipal hospital in Ghana Open
Introduction Serum neutrophil gelatinase-associated lipocalin (sNGAL), a renal tubular marker, and Neutrophil-to-Lymphocyte Ratio (NLR), a haematological inflammatory marker are two biomarkers that have recently received attention, because…
View article: Prevalence of Hepatitis B Viral Infection in Pregnant Women at the Suhum Municipality, Ghana
Prevalence of Hepatitis B Viral Infection in Pregnant Women at the Suhum Municipality, Ghana Open
Background. Global prevalence of chronic hepatitis B virus (HBV) infection was estimated between 257 and 291 million since 2020, posing a great public health challenge. In Africa, an estimated 60 million cases of HBV were reported in the s…
View article: Mixed-methods exploration of the knowledge of young adults about blood donation processes; a one-center cross-sectional study in a tertiary institution
Mixed-methods exploration of the knowledge of young adults about blood donation processes; a one-center cross-sectional study in a tertiary institution Open
Ghana is a majority youthful population, but is only able to meet 60% of its annual blood donation requirements. Although tertiary students in Ghana may serve as important blood donor resource by virtue of their higher educational attainme…
View article: Lack of consensus in inter-laboratory haematology results in selected laboratories in the southern and northern zones of Ghana
Lack of consensus in inter-laboratory haematology results in selected laboratories in the southern and northern zones of Ghana Open
Objective: To assess the inter-laboratory comparability and intra-assay reproducibility of full blood count (FBC) results.Design: Exploratory cross-sectional study.Setting: Three and two selected medical laboratories in the northern and so…
View article: Quality of glycemic control in type 2 diabetes mellitus (T2DM) and its association with markers of coagulation and inhibitors of fibrinolysis: A case–control study in the Upper West Region, Ghana
Quality of glycemic control in type 2 diabetes mellitus (T2DM) and its association with markers of coagulation and inhibitors of fibrinolysis: A case–control study in the Upper West Region, Ghana Open
Background and Aims Type 2 diabetes mellitus (T2DM) individuals are at a higher risk of developing diabetes complications, with approximately 80% complication‐related mortality. The increased morbidity and mortality among T2DM patients are…
View article: Establishing pregnancy-specific haematological reference intervals in Ghana; a three-center cross-sectional study
Establishing pregnancy-specific haematological reference intervals in Ghana; a three-center cross-sectional study Open
Background Abnormal intra-pregnancy haematological variables are associated with adverse feto-maternal outcomes. However, the reference intervals (RIs) employed in sub-Saharan Africa to inform clinical decisions are generally imported. Sin…
View article: HBV Infection Is an Intermediate‐Risk Disease, Whereas Anaemia Is a Mild‐to‐Moderate Public Health Problem in Young Ghanaian Adults: A Four‐Year Retrospective Analysis of Students’ Medical Records
HBV Infection Is an Intermediate‐Risk Disease, Whereas Anaemia Is a Mild‐to‐Moderate Public Health Problem in Young Ghanaian Adults: A Four‐Year Retrospective Analysis of Students’ Medical Records Open
Background . In sub‐Saharan Africa, malaria, chronic viral diseases, nutritional deficiencies, and haemoglobinopathies are common causes of anaemia. Continual surveillance data is required to situate the anaemia and infectious disease burd…
View article: Coagulation Factors and Natural Anticoagulants as Surrogate Markers of Preeclampsia and Its Subtypes: A Case–Control Study in a Ghanaian Population
Coagulation Factors and Natural Anticoagulants as Surrogate Markers of Preeclampsia and Its Subtypes: A Case–Control Study in a Ghanaian Population Open
Preeclampsia (PE) is associated with endothelial injury and hemostatic abnormalities. However, the diagnostic role of coagulation parameters and natural anticoagulants in predicting PE has not been explored in Ghana. This study assessed pl…
View article: Patterns of hernia, haematological profile, and predictive ability of blood cell indices in pre-surgery patients; A case-control study in a district hospital in Ghana
Patterns of hernia, haematological profile, and predictive ability of blood cell indices in pre-surgery patients; A case-control study in a district hospital in Ghana Open
Introduction: The burden of hernia is disproportionately high in low-to-middle income countries, due to the lack of fundamental resources needed to effectively diagnose and manage cases. This study explored the patterns of hernia, haematol…
View article: Haematological Profile in Pre-Surgery Hernia Patients: A Case-Control Study in Ghana
Haematological Profile in Pre-Surgery Hernia Patients: A Case-Control Study in Ghana Open
Introduction: The burden of hernia is disproportionately high in low-to-middle-income countries, due to the lack of fundamental resources needed to effectively diagnose and manage cases. The patterns of hernia, the haematological profile, …
View article: Anaemia Prevalence More Than Doubles in an Academic Year in a Cohort of Tertiary Students: A Repeated-Measure Study in Cape Coast, Ghana
Anaemia Prevalence More Than Doubles in an Academic Year in a Cohort of Tertiary Students: A Repeated-Measure Study in Cape Coast, Ghana Open
Background. The stress of academic life may predispose young adults to poor dietary habits, which could potentially precipitate nutritional deficiencies, such as iron deficiency. This study evaluated factors predictive of optimal iron stor…
View article: Poor haemoglobin-haematocrit agreement in apparently healthy adult population; a cross-sectional study in Cape Coast Metropolis, Ghana
Poor haemoglobin-haematocrit agreement in apparently healthy adult population; a cross-sectional study in Cape Coast Metropolis, Ghana Open
The low DWI is suggestive that measuring plasma volume and/or haemoglobin mass may be required to correctly diagnose anaemia.
View article: Crude extracts from Allium cepa skin and Sorghum bicolor seed can provide as non-toxic and eco-friendly cytoplasmic stains
Crude extracts from Allium cepa skin and Sorghum bicolor seed can provide as non-toxic and eco-friendly cytoplasmic stains Open
Allium cepa skin and Sorghum bicolor seed extracts are good cytoplasmic dyes when used as counterstain for haematoxylin.