Patrick Bontems
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View article: Drugs in focus: Botulinum toxin in the therapy of gastrointestinal disorders in children
Drugs in focus: Botulinum toxin in the therapy of gastrointestinal disorders in children Open
What is Known Botulinum toxin (BoNT) causes muscle relaxation by inhibiting acetylcholine release from presynaptic motor neurons at the neuromuscular junction. What is New In children with achalasia, BoNT can be considered only in patients…
View article: Updated joint ESPGHAN/NASPGHAN guidelines for management of <i>Helicobacter pylori</i> infection in children and adolescents (2023)
Updated joint ESPGHAN/NASPGHAN guidelines for management of <i>Helicobacter pylori</i> infection in children and adolescents (2023) Open
Background Evolving epidemiological data and increasing antibiotic resistance mandate an update of the European and North American Societies of Pediatric Gastroenterology, Hepatology and Nutrition guidelines. Methods Certainty of evidence …
View article: <i>Helicobacter pylori</i> Eradication Rate Using Stool Antigen Test in Vietnamese Children: A Prospective Multicenter Study
<i>Helicobacter pylori</i> Eradication Rate Using Stool Antigen Test in Vietnamese Children: A Prospective Multicenter Study Open
Objectives: This study assessed the diagnostic value of a monoclonal immunoassay stool antigen test (HpSA) for Helicobacter pylori (H. pylori ) infection and the eradication outcomes. Methods: Children undergoing digestive endoscopy at 2 C…
View article: Helicobacter pylori Infections in Children
Helicobacter pylori Infections in Children Open
In the context of epidemiology, host response, disease presentation, diagnosis, and treatment management, the manifestation of Helicobacter pylori (H. pylori) infection diverges between children and adults. H. pylori infection stands out a…
View article: Antibiotic resistance and heteroresistance in <i>Helicobacter pylori</i> isolates from symptomatic Vietnamese children: A prospective multicenter study
Antibiotic resistance and heteroresistance in <i>Helicobacter pylori</i> isolates from symptomatic Vietnamese children: A prospective multicenter study Open
Background Antibiotic resistance of Helicobacter pylori (H. pylori) is increasing worldwide, with geographical variations, impacting the treatment outcomes. This study assessed the antibiotic resistance patterns of H. pylori in Vietnamese …
View article: Helicobacter pylori Infection and Peptic Ulcer Disease in Symptomatic Children in Southern Vietnam: A Prospective Multicenter Study
Helicobacter pylori Infection and Peptic Ulcer Disease in Symptomatic Children in Southern Vietnam: A Prospective Multicenter Study Open
Background: Helicobacter pylori (H. pylori) remains a major cause of gastroduodenal diseases. We aimed to evaluate the burden of this infection, particularly peptic ulcer disease in Vietnamese children. Methods: We enrolled consecutive chi…
View article: Factors Associated With Helicobacter Pylori Infection Among School-Aged Children From a High Prevalence Area in Vietnam
Factors Associated With Helicobacter Pylori Infection Among School-Aged Children From a High Prevalence Area in Vietnam Open
Objectives: The study aimed to identify prevalence of H. pylori infection and associated risk factors among pupils of Ho Chi Minh city (HCMC). Methods: A total of 1,476 pupils aged 6–15 years were enrolled in this cross-sectional study usi…
View article: Complications of Percutaneous and Surgical Gastrostomy Placements in Children
Complications of Percutaneous and Surgical Gastrostomy Placements in Children Open
Objectives: Gastrostomy placement is a standard procedure for children requiring enteral feeding for more than 3–6 weeks. Various techniques have been described (percutaneous endoscopic, laparoscopy, and laparotomy), and many complications…
View article: Belgian consensus for Helicobacter pylori management 2023
Belgian consensus for Helicobacter pylori management 2023 Open
Helicobacter pylori (H. pylori) infection causes chronic gastritis, peptic ulcers and gastric cancer. Although H. pylori prevalence is decreasing worldwide, regional variations exist in Europe, with the lowest infection prevalence in North…
View article: High Prevalence of Helicobacter pylori Infection Among School-Aged Children in Ho Chi Minh City, VietNam
High Prevalence of Helicobacter pylori Infection Among School-Aged Children in Ho Chi Minh City, VietNam Open
Objectives: There is no study on Helicobacter pylori ( H. pylori ) infection in pupils of Ho Chi Minh city (HCMC), the most overcrowded city in Vietnam. Therefore, the aim of this study was to estimate the prevalence of H. pylori and its g…
View article: Management of Helicobacter pylori infection in paediatric patients in Europe: results from the EuroPedHp Registry
Management of Helicobacter pylori infection in paediatric patients in Europe: results from the EuroPedHp Registry Open
Purpose The EuroPedHp-registry aims to monitor guideline-conform management, antibiotic resistance, and eradication success of 2-week triple therapy tailored to antibiotic susceptibility (TTT) in Helicobacter pylori- infected children. Met…
View article: Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopy Facilities
Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopy Facilities Open
Introduction: There is increasing international recognition of the impact of variability in endoscopy facilities on procedural quality and outcomes. There is also growing precedent for assessing the quality of endoscopy facilities at regio…
View article: Overview of the Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopy
Overview of the Pediatric Endoscopy Quality Improvement Network Quality Standards and Indicators for Pediatric Endoscopy Open
Introduction: Pediatric‐specific quality standards for endoscopy are needed to define best practices, while measurement of associated indicators is critical to guide quality improvement. The international Pediatric Endoscopy Quality Improv…
View article: Percutaneous Endoscopic Gastrostomy in Children
Percutaneous Endoscopic Gastrostomy in Children Open
Background: The European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) position paper from 2015 on percutaneous endoscopic gastrostomy (PEG) required updating in the light of recent clinical knowledge and dat…
View article: Efficacy and safety of bismuth‐based quadruple therapy for<i>Helicobacter</i><i>pylori</i>eradication in children
Efficacy and safety of bismuth‐based quadruple therapy for<i>Helicobacter</i><i>pylori</i>eradication in children Open
Objectives To evaluate the efficacy and safety of a 10‐day quadruple therapy containing colloidal bismuth sub‐citrate (CBS), esomeprazole (ESO), amoxicillin (AMO), and metronidazole (MET) for Helicobacter pylori ( H . pylori ) eradication …
View article: Significant variations across European centres in implementing recommended guidelines for the paediatric gastroenterology endoscopy suite during the COVID‐19 pandemic
Significant variations across European centres in implementing recommended guidelines for the paediatric gastroenterology endoscopy suite during the COVID‐19 pandemic Open
Background: The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) published recommendations regarding protection for the paediatric endoscopist during the coronavirus 2019 (COVID‐19) pandemic.The aim of t…
View article: ID: 3526084 INTERNATIONAL CONSENSUS ON PEDIATRIC ENDOSCOPY REPORTING ELEMENTS: A REPORT FROM THE PEDIATRIC ENDOSCOPY QUALITY IMPROVEMENT NETWORK (PENQUIN)
ID: 3526084 INTERNATIONAL CONSENSUS ON PEDIATRIC ENDOSCOPY REPORTING ELEMENTS: A REPORT FROM THE PEDIATRIC ENDOSCOPY QUALITY IMPROVEMENT NETWORK (PENQUIN) Open
View article: How did the COVID-19 pandemic change the practice of Paediatric Endoscopists in Europe?
How did the COVID-19 pandemic change the practice of Paediatric Endoscopists in Europe? Open
Background: As endoscopists are at risk to get infected by the novel Coronavirus SARS-CoV-2 during endoscopic procedures, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) published recommendations re…
View article: <i>Helicobacter pylori</i> Infection in Pediatric Patients Living in Europe
<i>Helicobacter pylori</i> Infection in Pediatric Patients Living in Europe Open
Objectives: The aim of the study was to assess clinical presentation, endoscopic findings, antibiotic susceptibility and treatment success of Helicobacter pylori ( H. pylori ) infected pediatric patients. Methods: Between 2013 and 2016, 23…
View article: Mo1988 THE PEDIATRIC ENDOSCOPY PRACTICE IN EUROPE: PRELIMINARY RESULTS OF A WEB-BASED SURVEY ON BEHALF OF THE ENDOSCOPY SPECIAL INTEREST GROUP OF EUROPEAN SOCIETY OF GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION (ESPGHAN)
Mo1988 THE PEDIATRIC ENDOSCOPY PRACTICE IN EUROPE: PRELIMINARY RESULTS OF A WEB-BASED SURVEY ON BEHALF OF THE ENDOSCOPY SPECIAL INTEREST GROUP OF EUROPEAN SOCIETY OF GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION (ESPGHAN) Open
View article: Evolution of <i>Helicobacter pylori</i> associated with gastroduodenal ulcers or erosions in children over the past 23 years: Decline or steady state?
Evolution of <i>Helicobacter pylori</i> associated with gastroduodenal ulcers or erosions in children over the past 23 years: Decline or steady state? Open
Background Recent data suggest that in children, the proportion of gastroduodenal ulcers/erosions associated with Helicobacter pylori infection is currently lower than expected. In this study, we trace this proportion over two decades. Met…
View article: Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection
Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection Open
View article: Current practice of gastro-intestinal endoscopy in children in Belgium
Current practice of gastro-intestinal endoscopy in children in Belgium Open
View article: Helicobacter pylori Infection in Pediatric Patients: Update on Diagnosis and Eradication Strategies
Helicobacter pylori Infection in Pediatric Patients: Update on Diagnosis and Eradication Strategies Open
Helicobacter pylori infection is acquired mainly in childhood and remains an essential cause of peptic ulcer disease and gastric cancer. This article provides commentary on the last ESPGHAN/NASPGHAN guidelines and on publications made afte…
View article: NEW INSIGHTS IN THE DIAGNOSIS AND MANAGEMENT OF HIRSCHSPRUNG’S DISEASE
NEW INSIGHTS IN THE DIAGNOSIS AND MANAGEMENT OF HIRSCHSPRUNG’S DISEASE Open
Hirschsprung’s disease is a common pathology in pediatric surgery. Besides, long-term outcome of surgically-treated patients remains a crucial issue. The management of Hirschsprung’s disease has remarkably advanced over the years, but diff…
View article: Interest of Anorectal Manometry During Long-term Follow-up of Patients Operated on for Hirschsprung's Disease
Interest of Anorectal Manometry During Long-term Follow-up of Patients Operated on for Hirschsprung's Disease Open
Anorectal manometry is an objective method providing useful information that could guide a more adapted management in patients with defecation disorders after Hirschsprung's disease operation.
View article: Long-term Outcomes with Anti-TNF Therapy and Accelerated Step-up in the Prospective Pediatric Belgian Crohnʼs Disease Registry (BELCRO)
Long-term Outcomes with Anti-TNF Therapy and Accelerated Step-up in the Prospective Pediatric Belgian Crohnʼs Disease Registry (BELCRO) Open
Anti-TNF therapy and accelerated step-up in older patients with more severe disease leads to beneficial long-term outcomes.
View article: Joint ESPGHAN/NASPGHAN Guidelines for the Management of <i>Helicobacter pylori</i> in Children and Adolescents (Update 2016)
Joint ESPGHAN/NASPGHAN Guidelines for the Management of <i>Helicobacter pylori</i> in Children and Adolescents (Update 2016) Open
Background: Because of the changing epidemiology of Helicobacter pylori infection and low efficacy of currently recommended therapies, an update of the European Society for Paediatric Gastroenterology Hepatology and Nutrition/North America…
View article: DOP056. Pharmacokinetics and exposure-response relationships of golimumab in paediatric patients with moderate-to-severe ulcerative colitis: results from a multicentre open-label study
DOP056. Pharmacokinetics and exposure-response relationships of golimumab in paediatric patients with moderate-to-severe ulcerative colitis: results from a multicentre open-label study Open
Background: Crohn's disease has been linked to changes in the microbiome and to pathobionts such as adherent strains of E.coli.These strains may exist in the lumen, upon the epithelium as a biofilm or as intracellular bacteria in macrophag…
View article: P152. Faecal calprotectin 100 ug/g and 50 ug/g predict endoscopic and histologic remission: a prospective study in quiescent ulcerative colitis
P152. Faecal calprotectin 100 ug/g and 50 ug/g predict endoscopic and histologic remission: a prospective study in quiescent ulcerative colitis Open
Background: Faecal calprotectin (FC) level correlates with mucosal inflammation.However, cut-off values of FC in identifying endoscopic and histologic remission in patients with quiescent ulcerative colitis (UC) remain unclear.Methods: In …