Patrick C. Strasser
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View article: Inflammation awakens dormant cancer cells by modulating the epithelial–mesenchymal phenotypic state
Inflammation awakens dormant cancer cells by modulating the epithelial–mesenchymal phenotypic state Open
The awakening of dormant disseminated cancer cells appears to be responsible for the clinical relapses of patients whose primary tumors have been successfully cured months and even years earlier. In the present study, we demonstrate that d…
View article: Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions
Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions Open
Interleukins are secreted proteins that regulate immune responses. Among these, the interleukin 12 (IL-12) family holds a central position in inflammatory and infectious diseases. Each family member consists of an α and a β subunit that to…