Patrick Diaz
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View article: Selected Factors Affecting the Subsectors of the Philippine Agriculture: A Panel Regression Analysis
Selected Factors Affecting the Subsectors of the Philippine Agriculture: A Panel Regression Analysis Open
The study examined the effects of exports to Gross Domestic Product (GDP), employment, and production loans granted in the GDP agriculture of the Philippines. This paper employed descriptive and quantitative techniques to analyze the behav…
View article: Potential Benefit of Add-on Δ9-Tetrahydrocannabinol in Pediatric Drug-Resistant Epilepsy: A Case Series
Potential Benefit of Add-on Δ9-Tetrahydrocannabinol in Pediatric Drug-Resistant Epilepsy: A Case Series Open
We present five cases of pediatric drug-resistant epilepsy (DRE) that failed management using high cannabidiol (CBD) doses, but had significant reduction in seizure frequency with reintroduction or increasing doses of tetrahydrocannabinol …
View article: Evaluation of Patient Reported Safety and Efficacy of Cannabis From a Survey of Medical Cannabis Patients in Canada
Evaluation of Patient Reported Safety and Efficacy of Cannabis From a Survey of Medical Cannabis Patients in Canada Open
With the medical use of cannabis permitted in Canada since 2001, patients seek to use this botanical drug to treat a range of medical conditions. However, many healthcare practitioners express the need for further scientific evidence aroun…
View article: Implementation of a Virtual Rapid Access Epilepsy Clinic
Implementation of a Virtual Rapid Access Epilepsy Clinic Open
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View article: Human Pharmacokinetic Parameters of Orally Administered Δ<sup>9</sup>-Tetrahydrocannabinol Capsules Are Altered by Fed Versus Fasted Conditions and Sex Differences
Human Pharmacokinetic Parameters of Orally Administered Δ<sup>9</sup>-Tetrahydrocannabinol Capsules Are Altered by Fed Versus Fasted Conditions and Sex Differences Open
Background: There is variability in the reported Δ9-tetrahydrocannabinol (THC) and 11-hydroxy-tetrahydrocannabinol (11-OH-THC) pharmacokinetic (PK) and pharmacodynamic (PD) parameters between studies and there is limited …
View article: Framing of the Opioid Problem in Cancer Pain Management in Canada
Framing of the Opioid Problem in Cancer Pain Management in Canada Open
Two guidelines about opioid use in chronic pain management were published in 2017: the Canadian Guideline for Opioids for Chronic Non-Cancer Pain and the European Pain Federation position paper on appropriate opioid use in chronic pain man…
View article: Symptom clusters using the EORTC QLQ-C15-PAL in palliative radiotherapy
Symptom clusters using the EORTC QLQ-C15-PAL in palliative radiotherapy Open
Fluctuation of symptom clusters was observed in a short time frame following palliative RT. Although clusters were dynamic, several items tended to cluster together. Further research is required to validate these clusters.
View article: Modulating the endocannabinoid pathway as treatment for peripheral neuropathic pain: a selected review of preclinical studies
Modulating the endocannabinoid pathway as treatment for peripheral neuropathic pain: a selected review of preclinical studies Open
Chemotherapy-induced neuropathic pain is a distressing and commonly occurring side effect of many commonly used chemotherapeutic agents, which in some cases may prevent cancer patients from being able to complete their treatment. Cannabino…
View article: Symptomatic palliation with radiotherapy in extensive heterotopic ossifications
Symptomatic palliation with radiotherapy in extensive heterotopic ossifications Open
Heterotopic ossification (HTO) is the dystrophic formation of mature lamellar bone outside the confines of normal osseous tissues. It is frequently a complication which occurs following traumatic insult, both iatrogenic and non-iatrogenic,…
View article: A selective review of medical cannabis in cancer pain management
A selective review of medical cannabis in cancer pain management Open
Insufficient management of cancer-associated chronic and neuropathic pain adversely affects patient quality of life. Patients who do not respond well to opioid analgesics, or have severe side effects from the use of traditional analgesics …