Patrick Dumont
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View article: Political Polarization of Belief in Climate Change and Its Impact on Policy Support Among Politicians and Citizens From Eight Countries
Political Polarization of Belief in Climate Change and Its Impact on Policy Support Among Politicians and Citizens From Eight Countries Open
Despite scientific consensus, beliefs in human-driven climate change are often influenced by political orientation. Although this political polarization of beliefs may stall mitigation policies, few studies have investigated politicians’ b…
View article: Politicians’ Theories of Voting Behavior
Politicians’ Theories of Voting Behavior Open
While political scientists regularly engage in spirited theoretical debates about elections and voting behavior, few have noticed that elected politicians also have theories of elections and voting. Here, we investigate politicians’ positi…
View article: Luxembourg: Political Developments and Data in 2022
Luxembourg: Political Developments and Data in 2022 Open
Luxembourg politics in 2022 was marked by the economic consequences of Russia's war against Ukraine. The government responded through policy packages negotiated with social partners. The decade‐long process of revamping the Constitution fi…
View article: Pieces of the puzzle? Coalition formation and tangential preferences
Pieces of the puzzle? Coalition formation and tangential preferences Open
The similarity of parties' policy preferences has long been considered an important determinant of whether they form a government coalition. That similarity has typically been assessed based on parties' respective locations in a policy spa…
View article: Supplementary Figure 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 270K, Relative pea3 mRNA and protein expression in TAC-V vs TAC-Pea3-V. Wound healing assay for TAC-V and TAC-Pea3-V cells treated or not with TGF-β1 and with or without Mitomycin C. Apoptosis measurement.
View article: Supplementary Methods from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Methods from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 93K
View article: Supplementary Table 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Table 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 22K, siRNA sequences used for the cyclin d2 AND pea3 knock-down experiments.
View article: Supplementary Figure 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 283K, Wound healing assay for TAC-V and TAC-Pea3-V cells transfected with ctrl or pea3 siRNAs and treated or not with TGF-β1. Western blot analysis of p27kip1 protein expression.
View article: Supplementary Table 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Table 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 22K, siRNA sequences used for the cyclin d2 AND pea3 knock-down experiments.
View article: Supplementary Figure 3 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 3 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 42K, Relative luciferase activity measured for the human cyclin d2 promoter. Alignment of the 55 bp Mouse, Rat and Human proximal cyclin d2 promoter region.
View article: Data from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Data from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
The Ets family transcription factor Pea3 (ETV4) is involved in tumorigenesis especially during the metastatic process. Pea3 is known to induce migration and invasion in mammary epithelial cell model systems. However, the molecular pathways…
View article: Supplementary Figure Legend from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure Legend from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 86K
View article: Supplementary Table 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Table 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 69K, Primers sets used for Q-PCR and ChIP experiments.
View article: Supplementary Figure 3 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 3 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 42K, Relative luciferase activity measured for the human cyclin d2 promoter. Alignment of the 55 bp Mouse, Rat and Human proximal cyclin d2 promoter region.
View article: Supplementary Figure 4 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 4 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 71K, Western blot analysis of Pea3 protein expression in the MMT and TAC cells. Effect of Pea3 and TGF-β1 on the expression of cell cycle related genes.
View article: Supplementary Figure Legend from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure Legend from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 86K
View article: Supplementary Table 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Table 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 69K, Primers sets used for Q-PCR and ChIP experiments.
View article: Data from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Data from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
The Ets family transcription factor Pea3 (ETV4) is involved in tumorigenesis especially during the metastatic process. Pea3 is known to induce migration and invasion in mammary epithelial cell model systems. However, the molecular pathways…
View article: Supplementary Figure 4 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 4 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 71K, Western blot analysis of Pea3 protein expression in the MMT and TAC cells. Effect of Pea3 and TGF-β1 on the expression of cell cycle related genes.
View article: Supplementary Methods from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Methods from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 93K
View article: Supplementary Figure 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 2 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 283K, Wound healing assay for TAC-V and TAC-Pea3-V cells transfected with ctrl or pea3 siRNAs and treated or not with TGF-β1. Western blot analysis of p27kip1 protein expression.
View article: Supplementary Figure 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells
Supplementary Figure 1 from Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells Open
PDF file - 270K, Relative pea3 mRNA and protein expression in TAC-V vs TAC-Pea3-V. Wound healing assay for TAC-V and TAC-Pea3-V cells treated or not with TGF-β1 and with or without Mitomycin C. Apoptosis measurement.
View article: Supplementary Figure 2 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Supplementary Figure 2 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
PDF file - 202K, Figure S2. Western blot analysis of c-Yes and YAP in human colon cancer cells HT29 and RKO cells treated by oxaliplatin and 5FU.
View article: Supplementary Table 1 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Supplementary Table 1 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
PDF file - 55K, Table S1. Expression of cell surface stem cell markers in parental HT29 cells, its 5FUresistant 5F7 and 5F31 clonal derivatives, 5FU- and oxaliplatin-resistant HT29FU and HT29OXA subpopulations.
View article: Supplementary Figure Legend from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Supplementary Figure Legend from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
PDF file - 50K
View article: Supplementary Figure 2 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Supplementary Figure 2 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
PDF file - 202K, Figure S2. Western blot analysis of c-Yes and YAP in human colon cancer cells HT29 and RKO cells treated by oxaliplatin and 5FU.
View article: Supplementary Methods from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Supplementary Methods from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
PDF file - 107K
View article: Data from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Data from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
Purpose: Metastasis and drug resistance are the major limitations in the survival and management of patients with cancer. This study aimed to identify the mechanisms underlying HT29 colon cancer cell chemoresistance acquired after s…
View article: Supplementary Figure 1 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Supplementary Figure 1 from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
PDF file - 309K, Figure S1. Expression of cancer stem cell phenotypes in 5FU-resistant 5F7 and 5F31 clones.
View article: Supplementary Figure Legend from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
Supplementary Figure Legend from Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis Open
PDF file - 50K