Patrick Eichenberger
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View article: Spore germination: Two ion channels are better than one
Spore germination: Two ion channels are better than one Open
Germination is the process by which spores emerge from dormancy. Although spores can remain dormant for decades, the study of germination is an active field of research. In this issue of Genes & Development , Gao and colleagues (pp. 31–45)…
View article: Identification of <scp>CgeA</scp> as a glycoprotein that anchors polysaccharides to the spore surface in <i>Bacillus subtilis</i>
Identification of <span>CgeA</span> as a glycoprotein that anchors polysaccharides to the spore surface in <i>Bacillus subtilis</i> Open
The Bacillus subtilis spore is composed of a core, containing chromosomal DNA, surrounded by a cortex layer made of peptidoglycan, and a coat composed of concentric proteinaceous layers. A polysaccharide layer is added to the spore surface…
View article: Inference of Bacterial Small RNA Regulatory Networks and Integration with Transcription Factor-Driven Regulatory Networks
Inference of Bacterial Small RNA Regulatory Networks and Integration with Transcription Factor-Driven Regulatory Networks Open
Individual bacterial genomes can have dozens of small noncoding RNAs with largely unexplored regulatory functions. Although bacterial sRNAs influence a wide range of biological processes, including antibiotic resistance and pathogenicity, …
View article: Inference of bacterial small RNA regulatory networks and integration with transcription factor driven regulatory networks
Inference of bacterial small RNA regulatory networks and integration with transcription factor driven regulatory networks Open
Small non-coding RNAs (sRNAs) are key regulators of bacterial gene expression. Through complementary base pairing, sRNAs affect messenger RNA stability and translation efficiency. Here, we describe a network inference approach designed to …
View article: Bacillus subtilis Spore Resistance to Simulated Mars Surface Conditions
Bacillus subtilis Spore Resistance to Simulated Mars Surface Conditions Open
In a Mars exploration scenario, knowing if and how highly resistant Bacillus subtilis spores would survive on the Martian surface is crucial to design planetary protection measures and avoid false positives in life-detection experiments. T…
View article: Contributions of crust proteins to spore surface properties in <i>Bacillus subtilis</i>
Contributions of crust proteins to spore surface properties in <i>Bacillus subtilis</i> Open
Summary Surface properties, such as adhesion and hydrophobicity, constrain dispersal of bacterial spores in the environment. In Bacillus subtilis , these properties are influenced by the outermost layer of the spore, the crust . Previous w…
View article: SpoVID functions as a non‐competitive hub that connects the modules for assembly of the inner and outer spore coat layers in <i>Bacillus subtilis</i>
SpoVID functions as a non‐competitive hub that connects the modules for assembly of the inner and outer spore coat layers in <i>Bacillus subtilis</i> Open
Summary During sporulation in Bacillus subtilis , a group of mother cell‐specific proteins guides the assembly of the coat, a multiprotein structure that protects the spore and influences many of its environmental interactions. SafA and Co…
View article: Low pressure plasma inactivation of Bacillus subtilis spores: insights into the mechanisms of spore resistance
Low pressure plasma inactivation of Bacillus subtilis spores: insights into the mechanisms of spore resistance Open
Being the most resistant form of a biological system, spores of Bacillus subtilis are very resistant against a broad spectrum of sterilization methods and, therefore, are commonly used as a biological indicator in order to verify the funct…