Patrick Gad Iradukunda
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View article: Understanding Malaria Treatment Adherence in Rwanda: Implications for Artemisinin Resistance
Understanding Malaria Treatment Adherence in Rwanda: Implications for Artemisinin Resistance Open
Prompt diagnosis and effective treatment are key malaria interventions that rely on community knowledge and adherence to treatment. With the emergence of artemisinin resistance in Rwanda, ensuring optimal malaria treatment practices within…
View article: Gender-Associated Factors on the Occurrence and Prevalence of Zero-Dose Children in Sub-Saharan Africa: A Critical Literature Review
Gender-Associated Factors on the Occurrence and Prevalence of Zero-Dose Children in Sub-Saharan Africa: A Critical Literature Review Open
Background: Immunisation remains one of the most effective and cost-efficient public health interventions for preventing infectious diseases in children. Despite global progress, Sub-Saharan Africa (SSA) continues to face challenges in ach…
View article: Strategies for mitigating emerging artemisinin-based antimalarial drug resistance in Rwanda: a promising approach for managing therapies in malaria-endemic countries
Strategies for mitigating emerging artemisinin-based antimalarial drug resistance in Rwanda: a promising approach for managing therapies in malaria-endemic countries Open
Malaria treatment failures associated with reduced efficacy of chloroquine (CQ) and amodiaquine (AQ) antimalarial drugs emerged in Rwanda during the 1980s, prompting the policy shift towards adopting artemisinin-based combination therapies…
View article: Mapping Plasmodium falciparum mutations in Africa: A critical review of emerging drug resistance and implications for malaria control
Mapping Plasmodium falciparum mutations in Africa: A critical review of emerging drug resistance and implications for malaria control Open
View article: Understanding Malaria Treatment Adherence in Rwanda: Implications for Artemisinin Resistance
Understanding Malaria Treatment Adherence in Rwanda: Implications for Artemisinin Resistance Open
Prompt diagnosis and effective treatment are key malaria interventions that rely on community knowledge and adherence to treatment. With the emergence of artemisinin resistance in Rwanda, ensuring optimal malaria treatment practices within…
View article: Enhancing Global Health Security in Sub-Saharan Africa: The case for integrated One Health surveillance against zoonotic diseases and environmental threats
Enhancing Global Health Security in Sub-Saharan Africa: The case for integrated One Health surveillance against zoonotic diseases and environmental threats Open
View article: Leveraging risk communication and community engagement and lessons from previous outbreaks to strengthen a Public Health response: A case study of Disease X in the Panzi region, DRC
Leveraging risk communication and community engagement and lessons from previous outbreaks to strengthen a Public Health response: A case study of Disease X in the Panzi region, DRC Open
On 08 December 2024, the World Health Organization (WHO) reported an outbreak of Disease X in the Panzi Health Zone, Kwango province, Democratic Republic of the Congo (DRC). This unknown pathogen, with 406 cases and 31 deaths at the time o…
View article: Global health development aid initiatives and the quality of medical laboratory services in sub-Saharan Africa: a narrative review
Global health development aid initiatives and the quality of medical laboratory services in sub-Saharan Africa: a narrative review Open
View article: Bridging the gap: identifying barriers and strategies for widespread implementation of long-acting injectable antiretroviral therapy in Sub-Saharan Africa: a scoping review
Bridging the gap: identifying barriers and strategies for widespread implementation of long-acting injectable antiretroviral therapy in Sub-Saharan Africa: a scoping review Open
Not applicable.
View article: Immunization Coverage, Equity, and Access for Children with Disabilities: A Scoping Review of Challenges, Strategies, and Lessons Learned to Reduce the Number of Zero-Dose Children
Immunization Coverage, Equity, and Access for Children with Disabilities: A Scoping Review of Challenges, Strategies, and Lessons Learned to Reduce the Number of Zero-Dose Children Open
Background: Children with disabilities, particularly in low- and middle-income countries (LMICs), face heightened risks of vaccine-preventable diseases due to a range of systemic and social barriers. Although immunization is a fundamental …
View article: Antimicrobial Resistance and Its Impact on Food Safety Determinants Along the Beef Value Chain in Sub-Saharan Africa—A Scoping Review
Antimicrobial Resistance and Its Impact on Food Safety Determinants Along the Beef Value Chain in Sub-Saharan Africa—A Scoping Review Open
Antimicrobial resistance (AMR) poses a significant threat to human, animal, and public health, particularly in Sub-Saharan Africa (SSA), where the beef sector is vital to food security and livelihoods. We conducted a scoping review to expl…
View article: From COVID-19 Pandemic Pivot to Progress: Blended Work as a Pathway to Greener African Cities
From COVID-19 Pandemic Pivot to Progress: Blended Work as a Pathway to Greener African Cities Open
The COVID-19 pandemic, caused by SARS-CoV-2, disrupted work and life patterns worldwide, underscoring the urgency of addressing climate change. Despite contributing minimally to global greenhouse gas (GHG) emissions, Africa faces dispropor…
View article: Undetectable = Untransmittable (U = U): insights from people living with HIV attending health facilities in Rwanda
Undetectable = Untransmittable (U = U): insights from people living with HIV attending health facilities in Rwanda Open
View article: Geographic Trends of WHO-Prequalified Pharmaceuticals: Strategic Insights into Strengthening Local Manufacturing in Africa Towards Addressing Disease Burden
Geographic Trends of WHO-Prequalified Pharmaceuticals: Strategic Insights into Strengthening Local Manufacturing in Africa Towards Addressing Disease Burden Open
View article: Evolving Landscape of Sickle Cell Anemia Management in Africa: A Critical Review
Evolving Landscape of Sickle Cell Anemia Management in Africa: A Critical Review Open
Sickle cell disease (SCD) is a prevalent inherited blood disorder, particularly affecting populations in Africa. This review examined the disease’s burden, its diverse clinical presentations, and the challenges associated with its manageme…
View article: Bridging the Gap: Identifying Barriers and Strategies for Widespread Implementation of Long-acting Injectable Antiretroviral ART in Sub-Saharan Africa: A Scoping Review
Bridging the Gap: Identifying Barriers and Strategies for Widespread Implementation of Long-acting Injectable Antiretroviral ART in Sub-Saharan Africa: A Scoping Review Open
Background Long-acting injectable antiretroviral therapy (LAI ART) presents a new approach to HIV treatment and addressing the challenges of daily oral ART in Sub-Saharan Africa (SSA) remains paramount. This review collates existing litera…
View article: Molecular characterization of Ebola virus, immune response, and therapeutic challenges: a narrative review
Molecular characterization of Ebola virus, immune response, and therapeutic challenges: a narrative review Open
The Ebola virus (EBOV) remains a major public health challenge due to its complex structure and the lack of appropriate and effective vaccines and therapies. This review characterizes the Ebola virus, its immune response, and its therapeut…
View article: An Extensive Computational Investigation of <i>Mycobacterium tuberculosis</i> Pantothenate Synthetase Inhibitors from Diverse‐Lib Compounds Library
An Extensive Computational Investigation of <i>Mycobacterium tuberculosis</i> Pantothenate Synthetase Inhibitors from Diverse‐Lib Compounds Library Open
Antibiotics have played a crucial role in significantly reducing the incidence of tuberculosis (TB) infection worldwide. Even before the mid‐20 th century, the mortality rate of TB onset within five years was around 50 %. So, the introduct…
View article: Mpox in East Africa: Learning from COVID-19 and Ebola to Strengthen Public Health Responses
Mpox in East Africa: Learning from COVID-19 and Ebola to Strengthen Public Health Responses Open
The Africa Centers for Disease Control and Prevention declared mpox a Public Health Emergency of Continental Security (PHECS) in Africa. African public health systems have moved to mobilize a response against a backdrop of inherent signifi…
View article: A critical review of mpox outbreaks, risk factors, and prevention efforts in Africa: lessons learned and evolving practices
A critical review of mpox outbreaks, risk factors, and prevention efforts in Africa: lessons learned and evolving practices Open
The prevention and control of mpox in Africa require an improvement in community education, vaccination, disease surveillance, and infection control measures.
View article: COVID-19 and mental health services in Sub-Saharan Africa: A critical literature review
COVID-19 and mental health services in Sub-Saharan Africa: A critical literature review Open
View article: Undetectable equals untransmissible: knowledge, attitude, and practice among HIV-negative clients attending selected health facilities in Rwanda
Undetectable equals untransmissible: knowledge, attitude, and practice among HIV-negative clients attending selected health facilities in Rwanda Open
HIV/AIDS epidemic continues to challenge public health, particularly in Sub-Saharan Africa (SSA). In 2018, the UNAIDS launched the Undetectable equals Untransmissible (U=U) approach which states that people living with HIV (PLHIV) on antir…
View article: Epidemiological surveillance of enteric viral diseases using wastewater in Africa – A rapid review
Epidemiological surveillance of enteric viral diseases using wastewater in Africa – A rapid review Open
Viral enteric pathogens remain an important cause of diarrhoeal outbreaks among children in sub-Saharan Africa (SSA). Consequently, diarrhoeal illness remains a significant cause of morbidity and mortality in the under-fives in SSA. These …
View article: Risk of mortality in HIV-infected COVID-19 patients: A systematic review and meta-analysis
Risk of mortality in HIV-infected COVID-19 patients: A systematic review and meta-analysis Open
View article: Risk Factors for COVID-19 Infection Among Healthcare Workers. A First Report From a Living Systematic Review and meta-Analysis
Risk Factors for COVID-19 Infection Among Healthcare Workers. A First Report From a Living Systematic Review and meta-Analysis Open
CRD42020193508 available for public comments via the link below https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020193508).
View article: Unpacking the Implications of SARS-CoV-2 Breakthrough Infections on COVID-19 Vaccination Programs
Unpacking the Implications of SARS-CoV-2 Breakthrough Infections on COVID-19 Vaccination Programs Open
Despite an array of preventive global public health interventions, SARS-CoV-2 has continued to spread significantly, infecting millions of people across the globe weekly. Newer variants of interest and concern have continued to emerge, pla…
View article: Utilization of SARS-CoV-2 Wastewater Surveillance in Africa—A Rapid Review
Utilization of SARS-CoV-2 Wastewater Surveillance in Africa—A Rapid Review Open
Wastewater-based epidemiology for SARS-CoV-2 RNA detection in wastewater is desirable for understanding COVID-19 in settings where financial resources and diagnostic facilities for mass individual testing are severely limited. We conducted…
View article: COVID-19 Prevalence among Healthcare Workers. A Systematic Review and Meta-Analysis
COVID-19 Prevalence among Healthcare Workers. A Systematic Review and Meta-Analysis Open
Understanding the burden of SARS-CoV-2 infections among healthcare workers is a critical component to inform occupational health policy and strategy. We conducted a systematic review and meta-analysis to map and analayse the available glob…
View article: Medical laboratory professional’s week in Rwanda: a field report from the Simbi and Maraba communities
Medical laboratory professional’s week in Rwanda: a field report from the Simbi and Maraba communities Open
Background: In response to the need for interventions that facilitate the accessibility of medical services in poor communities, an outreach activity was organized in semi-rural areas of Maraba and Simbi sectors located in Huye district, S…
View article: Evaluating the availability of essential drugs for hypertension, diabetes and asthma in rural Rwanda, 2018
Evaluating the availability of essential drugs for hypertension, diabetes and asthma in rural Rwanda, 2018 Open
SETTING: Hypertension, diabetes mellitus and asthma are on the rise in developing countries, including Rwanda; there is thus a need to ensure uninterrupted drug availability. OBJECTIVES: To assess 1) the frequency and duration of drug stoc…