Patrick Gholam
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View article: Deep Learning on Basal Cell Carcinoma In Vivo Reflectance Confocal Microscopy Data
Deep Learning on Basal Cell Carcinoma In Vivo Reflectance Confocal Microscopy Data Open
Background: Extended skin malignancies of the head and neck region are among the most common cancer types and are associated with numerous diagnostic and therapeutical problems. The radical resection of skin cancer in the facial area often…
Ablative Fractional Laser-assisted Low-irradiance Photodynamic Therapy for Treatment of Actinic Keratoses in Organ Transplant Recipients: A Prospective, Randomized, Intraindividual Controlled Trial Open
Pain and inferior efficacy are major limiting factors of conventional photodynamic therapy for the field treatment of actinic keratoses in immunosuppressed organ transplant recipients. This prospective randomized controlled study evaluates…
Efficacy and safety of endovenous laser ablation with the 1470 nm diode laser using a novel optical probe Open
Objectives: Outcome assessment of a novel optical fiber probe for the 1470 nm diode laser under real-world conditions. Methods: Prospective clinical pilot study in 10 patients undergoing endovenous laser ablation with a follow-up period of…
Pulse rate and blood pressure changes during low‐irradiance PDT compared with conventional PDT in the treatment of facial actinic keratoses: A retrospective study Open
Background Conventional photodynamic therapy (c‐PDT) is a highly effective treatment for actinic keratoses. Besides pain as the main side effect, blood pressure (BP) increases and hypertensive crises may occur during treatment. Reducing th…
View article: In vivo reflectance confocal microscopy of wounds: feasibility of intraoperative basal cell carcinoma margin assessment
In vivo reflectance confocal microscopy of wounds: feasibility of intraoperative basal cell carcinoma margin assessment Open
The accuracy of in vivo RCM imaging of wound margins is comparable with a standard skin surface imaging. The intraoperative detection of BCC areas in wound margins is as precise as the standard skin imaging and may be supportive for surgic…
View article: Deep learning approach to predict sentinel lymph node status directly from routine histology of primary melanoma tumours
Deep learning approach to predict sentinel lymph node status directly from routine histology of primary melanoma tumours Open
Our results indicate that the image classifier can predict lymph node status to some, albeit so far not clinically relevant, extent. It may do so by mostly detecting equivalents of factors on histological slides that are already known to c…